Results 201 to 210 of about 220,108 (349)

Feature and evaluation of drug delivery system targeted to receptor-mediated endocytosis.

, 1994
Yukio Kato, Yuichi Sugiyama
openalex   +2 more sources

Cathepsin K Aggravates Pulmonary Fibrosis Through Promoting Fibroblast Glutamine Metabolism and Collagen Synthesis

Advanced Science, EarlyView.
CTSK plays a critical role in pulmonary fibrosis. Excessive CTSK accumulation interacts with SNX9 to enhance TGF‐β1‐induced SMAD3 activation and GLS1 expression in fibroblasts, driving glutamine metabolism for collagen biosynthesis and exacerbating pulmonary fibrosis.
Mengting Chen, Xiaoxiao Meng, Yong Zhu, Dapeng Wang, Mengmeng Wang, Ziyuan Wang, Xue Tian, Jiaxiang Zhang, Zhiying Yue, Zhengfeng Yang, Ruilan Wang   +10 more
wiley   +1 more source

Receptor-Mediated Endocytosis of VEGF-A in Rat Liver Sinusoidal Endothelial Cells. [PDF]

Biomed Res Int, 2019
Mousavi SA, Skjeldal F, Fønhus MS, Haugen LH, Eskild W, Berg T, Bakke O.   +6 more
europepmc   +1 more source

Identification of a Major Cyclic AMP-Dependent Protein Kinase A Phosphorylation Site within the Cytoplasmic Tail of the Low-Density Lipoprotein Receptor-Related Protein: Implication for Receptor-Mediated Endocytosis [PDF]

, 2001
Yonghe Li, Peter van Kerkhof, María‐Paz Marzolo, Ger J. Strous, Guojun Bu   +4 more
openalex   +1 more source

Hypoglycemia Induces Diabetic Macrovascular Endothelial Dysfunction via Endothelial Cell PANoptosis, Macrophage Polarization, and VSMC Fibrosis

Advanced Science, EarlyView.
This study investigates hypoglycemia‐induced diabetic macrovascular endothelial dysfunction. It reveals that hypoglycemia triggers ZBP1‐dependent PANoptosis of endothelial cells, proinflammatory polarization of macrophages, and fibrosis of vascular smooth muscle cells (VSMCs) in diabetic mice.
Deyu Zuo, Yuce Peng, Guozhi Zhao, Zhesheng Cheng, Minghao Luo, Dingyi Lv, Shuting Chang, Na Li, Yanyao Huang, Xunjia Li, An He   +10 more
wiley   +1 more source

Precise Control of Intracellular Trafficking and Receptor-Mediated Endocytosis in Living Cells and Behaving Animals. [PDF]

Adv Sci (Weinh)
Chen SC, Zeng NJ, Liu GY, Wang HC, Lin TY, Tai YL, Chen CY, Fang Y, Chuang YC, Kao CL, Cheng H, Wu BH, Sun PC, Bayansan O, Chiu YT, Shih CH, Chung WH, Yang JB, Wang LH, Chiang PH, Chen CH, Wagner OI, Wang YC, Lin YC.   +23 more
europepmc   +1 more source

Heterologous Inhibition of G Protein-coupled Receptor Endocytosis Mediated by Receptor-specific Trafficking of β-Arrestins [PDF]

, 2001
Uwe Klein, Claudia Müller, Peter C. Chu, Mariel Birnbaumer, Mark von Zastrow   +4 more
openalex   +1 more source

Dynein‐Dependent Endo‐Lysosomal Degradation Drives Lewy Body Disorders Accompanied by Aβ Pathology

Advanced Science, EarlyView.
This study investigates the impact of Aβ plaques on α‐synuclein (αSyn) pathologies in dementia with Lewy bodies (DLB). Co‐culturing primary neurons with AD mouse brain slices reveals impaired dynein‐dependent organelle trafficking, affecting αSyn degradation. Activating Rab7 restores this process, reducing αSyn inclusions.
Linlin Zhou, Yuwei Wang, Yu Liu, Feipeng Zhu, Ge Gao, Chengjie Li, Pu Ai, Jingying Xu, Junxin Wang, Long Guo, Yuting Guan, Virginia Man‐Yee Lee, Jianjun Chen, Jialin Zheng, Qihui Wu   +14 more
wiley   +1 more source

Generation of a bloodstream form Trypanosoma brucei double glycosyltransferase null mutant competent in receptor-mediated endocytosis of transferrin. [PDF]

PLoS Pathog
Duncan SM, Carbajo CG, Nagar R, Zhong Q, Breen C, Ferguson MAJ, Tiengwe C.   +6 more
europepmc   +1 more source

Membrane capacitance recordings resolve dynamics and complexity of receptor-mediated endocytosis in Wnt signalling. [PDF]

Sci Rep, 2019
Bandmann V, Mirsanaye AS, Schäfer J, Thiel G, Holstein T, Mikosch-Wersching M.   +5 more
europepmc   +1 more source