Results 211 to 220 of about 150,460 (322)

Sugar Addiction: Neural Mechanisms and Health Implications

Brain and Behavior, Volume 15, Issue 7, July 2025.
This review synthesizes recent advances in understanding sugar addiction with a focus on its neurobiological mechanisms, health implications, and potential therapeutic interventions. ABSTRACT Purpose Sugar addiction, characterized by excessive cravings for high‐sugar foods, poses a significant health challenge in modern society.
Di Qin, Jiayu Qi, Fuqiang Shi, Zhihua Guo, Hongwu Li   +4 more
wiley   +1 more source

The regulation of rhythmic locomotion by motor cortical and dopaminergic inputs in the mouse striatum. [PDF]

Mol Brain
Zhang H, Su Y, Wu X, Gan WB.
europepmc   +1 more source

Immune Cell Proteins and Parkinson's Disease: A Mendelian Randomization Analysis of Causal Associations

Brain and Behavior, Volume 15, Issue 7, July 2025.
Mendelian randomization (MR) analysis was applied to elucidate the causal relationship between immune cell proteins and PD. Our study reveals a possible causal effect of immune cell proteins on the risk of PD and provides new ideas for the prevention and management of PD through immune cell proteins.
Haining Li, Jianhang He, Tingting Xuan, Shue Gu, Xiaoyan Niu, Yazhou Ren, Xiuping Zhan, Jiang Cheng   +7 more
wiley   +1 more source

The antipsychotics functional index (AFI) in schizophrenia. [PDF]

Front Pharmacol
Marinescu GC, Ifteni PI, Teodorescu A, Georgescu R.   +3 more
europepmc   +1 more source

Is Abrupt Withdrawal of Benzodiazepines a Risk Factor for Neuroleptic Malignant Syndrome? A Case Report With Single‐Dose Haloperidol

Clinical Case Reports, Volume 13, Issue 7, July 2025.
ABSTRACT Neuroleptic malignant syndrome (NMS) is a rare but life‐threatening reaction associated with the use of dopamine‐modulating agents, which presents with symptoms like high fever, muscle rigidity, and autonomic instability. It is known that both the use of dopamine receptor antagonists and the sudden withdrawal of dopamine receptor agonists can ...
Behnam Abbasi, Forouzan Elyasi, Masoud Aliyali   +2 more
wiley   +1 more source

Striatal cholinergic interneuron pause response requires Kv1 channels, is absent in dyskinetic mice, and is restored by dopamine D5 receptor inverse agonism. [PDF]

Elife
Tubert C, Paz RM, Stahl AM, Sanchez Armijos KM, Rela L, Murer MG.   +5 more
europepmc   +1 more source

Uncovering New Therapeutic Targets for Amyotrophic Lateral Sclerosis and Neurological Diseases Using Real‐World Data

Clinical Pharmacology &Therapeutics, Volume 118, Issue 1, Page 242-251, July 2025.
Although attractive for relevance to real‐world scenarios, real‐world data (RWD) is typically used for drug repurposing and not therapeutic target discovery. Repurposing studies have identified few effective options in neurological diseases such as the rare disease, amyotrophic lateral sclerosis (ALS), which has no disease‐modifying treatments ...
Mohammadali Alidoost, Jeremy Y. Huang, Georgia Dermentzaki, Anna S. Blazier, Giorgio Gaglia, Timothy R. Hammond, Francesca Frau, Mary Clare McCorry, Dimitry Ofengeim, Jennifer L. Wilson   +9 more
wiley   +1 more source

Blockade of Dopamine D3 Receptors in the Ventral Tegmental Area Mitigates Fear Memory Generalization. [PDF]

Int J Mol Sci
Fang X, Ding X, Wu N, Li J, Song R.
europepmc   +1 more source

PASTa: An Open‐Source Analysis and Signal Processing Toolbox for Fiber Photometry Data

Current Protocols, Volume 5, Issue 7, July 2025.
Abstract Fiber photometry is a rapidly growing technique to record real‐time neural signaling in awake, behaving subjects. However, the processing and analysis of photometry data streams can be complicated, and there is wide divergence in methods across the field.
Rachel M. Donka, Maxine K. Loh, Vaibhav R. Konanur, Mitchell F. Roitman, Jamie D. Roitman   +4 more
wiley   +1 more source

NMDA receptor involvement in dopaminergic modulation of neuroplasticity induced by paired associative stimulation. [PDF]

Int J Neuropsychopharmacol
Beaupain MC, Ghanavati E, Frese AM, Melo L, Kuo MF, Nitsche MA.   +5 more
europepmc   +1 more source