The Genetic Blueprint of Obesity: From Pathogenesis to Novel Therapies
ABSTRACT Obesity is a chronic metabolic disease characterized by disturbances in energy homeostasis, leading to excessive fat accumulation. The pathogenesis of the disease is shaped by a complex interplay of genetic, epigenetic, biological, psychological, and environmental factors.
Gašper Tonin+6 more
wiley +1 more source
Integrating impact of FSH isoforms, androgens and inhibin-B on follicular development based on a two-phase model of the follicular phase. [PDF]
Andersen CY.
europepmc +1 more source
ABSTRACT Polycystic ovary syndrome (PCOS) is a common endocrine disorder with a complex pathogenesis that includes disordered follicle development, hypothalamic–pituitary–ovarian (HPO) axis dysfunction, hyperandrogenemia, and insulin resistance. The risk of complications during pregnancy, such as gestational diabetes mellitus (GDM) and preeclampsia (PE)
Shaohua Zhang+5 more
wiley +1 more source
Soluble FSH receptors from the rat testis
D. Ryan, Maria L. Dufau, Kevin J. Catt
openaire +3 more sources
Tariff Troubles: Repercussions of Protectionist Policies on US Agriculture and the Trade Deficit
ABSTRACT The United States has increased protectionist measures since 2018 and has remained notably passive while other nations have pursued trade agreements. This change, coupled with the potential for future increased import tariffs, suggests impending changes in trade dynamics between the United States and the rest of the world. This study employs a
Tatjana Döbeling+2 more
wiley +1 more source
The Effect of the Intracervical Application of Follicle-Stimulating Hormone or Luteinizing Hormone on the Pattern of Expression of Gonadotrophin Receptors in the Cervix of Non-Pregnant Ewes [PDF]
Diaz+32 more
core +1 more source
Abstract This narrative review highlights the impact of exercise on vascular health in females over the lifespan with an emphasis on puberty, pregnancy and menopause. These events encompass substantial changes in sex hormone levels, particularly oestrogens and progesterone.
Kathleen B. Miller+2 more
wiley +1 more source
An in vivo screen identifies diverse domains that can act as force-dependent proteolytic switches for Notch activation. [PDF]
Baker FC+8 more
europepmc +1 more source
ACTH bioassay with isolated rat adrenal cells: ACTH activity of the porcins lipotropic peptide B [PDF]
Baur, X.+5 more
core +1 more source
The therapeutic role of exercise training during menopause for reducing vascular disease
Abstract Menopause marks a major milestone in female reproductive ageing. It is characterized by the cessation of ovarian function and a concomitant decline in hormones such as oestradiol. Subsequently, females undergoing menopausal transition experience a progressive increase in cardiovascular and cerebrovascular disease risk.
Conan L. H. Shing+4 more
wiley +1 more source