Results 81 to 90 of about 41,704 (276)

Responsiveness of bovine cumulus-oocyte-complexes (COC) to porcine and recombinant human FSH, and the effect of COC quality on gonadotropin receptor and Cx43 marker gene mRNAs during maturation in vitro [PDF]

, 2003
Substantially less development to the blastocyst stage occurs in vitro than in vivo and this may be due to deficiencies in oocyte competence. Although a large proportion of bovine oocytes undergo spontaneous nuclear maturation, less is known about ...
Calder, Michele D, Caveney, Anita N, Smith, Lawrence C, Watson, Andrew J   +3 more
core   +4 more sources

Emerging Perspectives on Gonadotropin Regulation in Vertebrates Revealed by the Discovery of FSH‐RH in Teleosts

BioEssays, EarlyView.
Regarding pituitary gonadotropin regulation, recent studies have shown that in mammals, FSH and LH are regulated by a single GnRH (solo GnRH model), whereas in teleosts, they are regulated by CCK (FSH‐RH) and GnRH (LH‐RH), respectively (dual GnRH model).
Daichi Kayo, Shun Kenny Uehara, Muhammad Rahmad Royan, Shinji Kanda   +3 more
wiley   +1 more source

Understanding Follicular Output Rate (FORT) and its Implications for POSEIDON Criteria

Frontiers in Endocrinology, 2019
The management of low prognosis patients in ART represents a challenge for reproductive specialists. Different profiles and biologic characteristics have been identified among these patients.
Michael Grynberg, Michael Grynberg, Michael Grynberg, Michael Grynberg, Julie Labrosse   +4 more
doaj   +1 more source

The Role of the Brain in the Pathogenesis and Physiology of Polycystic Ovary Syndrome (PCOS). [PDF]

, 2019
Polycystic ovary syndrome (PCOS) is a common reproductive endocrine disorder, affecting at least 10% of women of reproductive age. PCOS is typically characterized by the presence of at least two of the three cardinal features of hyperandrogenemia (high ...
Coutinho, Eulalia A, Kauffman, Alexander S   +1 more
core   +1 more source

Pharmacokinetics, Tolerability, and Biomarker Profile of the Neurokinin 3 Receptor Antagonist Fezolinetant in Healthy Japanese Individuals: A 2‐Part, Randomized, Phase 1 Study

Clinical Pharmacology in Drug Development, EarlyView.
Abstract This 2‐part, randomized, placebo‐controlled, double‐blind, Phase 1 study analyzed the pharmacokinetics, safety, and biomarker profile of fezolinetant in healthy Japanese individuals. Part 1: male participants received single doses of placebo or fezolinetant 15 or 60 mg.
Akira Koibuchi, Megumi Iwai, Kanji Komatsu, Kentaro Kuroishi, Mai Shibata, Masako Saito, Jace Nielsen, Jiayin Huang, Shunji Matsuki   +8 more
wiley   +1 more source

Pulsatile Hormonal Signaling to Extracellular Signal-Regulated Kinase: Exploring System Sensitivity to Gonadotropin-Releasing Hormone Pulse Frequency and Width [PDF]

, 2014
Gonadotropin-releasing hormone (GnRH) is secreted in brief pulses that stimulate synthesis and secretion of pituitary gonadotropin hormones and thereby mediate control of reproduction.
Armstrong, Armstrong, Armstrong, Armstrong, Barrell, Belchetz, Bliss, Bliss, Burger, Bédécarrats, Cardenas, Caunt, Caunt, Caunt, Chuderland, Ciccone, Clayton, Crowley, Cullen, Durham, Ferris, Haisenleder, Haisenleder, Kanasaki, Lawson, Markevich, Marshall, Marshall, Millar, Moenter, Naor, O'Byrne, Padmanabhan, Purvis, Reiss, Savoy-Moore, Shupnik, Sisk, Tomida, Tsaneva-Atanasova, Tsutsumi, Williams   +41 more
core   +1 more source

The Follicle-Stimulating Hormone (FSH) Receptor in Testis: Interaction with FSH, Mechanism of Signal Transduction, and Properties of the Purified Receptor1 [PDF]

Biology of Reproduction, 1989
The follicle-stimulating hormone (FSH) receptor purified from calf bovine testis membranes appears to be an oligomeric glycoprotein, consisting of 4 disulfide-linked monomers of molecular weight about 60,000 each. Polyclonal antibodies to the hormone binding sites of the receptor have been developed.
Bosukonda Dattatreyamurty, Leo E. Reichert   +1 more
openaire   +2 more sources

A review of the impact of micro‐ and nanoplastics on female reproduction: What we know and gaps in knowledge

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Micro‐and nanoplastics (MNPs) are breakdown products of plastics, and humans are exposed to these particles through air, water, food, and soil. There is a growing concern that human exposure to MNPs negatively impacts health. In this review we will discuss the potential health impact of MNPs on ovarian function and the hypothalamic–pituitary ...
Sanchayana Raghuvir, Shawn Alex, Deborah Clegg   +2 more
wiley   +1 more source

Perinatal Exposure to the Neonicotinoid Thiacloprid Impacts Transcription of Neuroplasticity and Neuroendocrine Markers in Mice but Not in the Zebrafish Model

Journal of Applied Toxicology, EarlyView.
ABSTRACT Neonicotinoids are widely used insecticides in agriculture, aquaculture, pet care, and urban pest control. Initially developed to selectively target the insect cholinergic system, their extensive use has raised concerns about adverse effects on nontarget vertebrates.
Kirthana Kunikullaya U, Zuzanna M. Baran, Pascal Coumailleau, Laetitia Guillot, Harry W. M. Steinbusch, Fatima Smagulova, Thierry D. Charlier   +6 more
wiley   +1 more source

Pharmacogenetics of FSH Action in the Female

Frontiers in Endocrinology, 2019
The purpose of a pharmacogenomic approach is to tailor treatment on the basis of an individual human genotype. This strategy is becoming increasingly common in medicine, and important results have been obtained in oncologic and antimicrobial therapies ...
Alessandro Conforti, Alberto Vaiarelli, Danilo Cimadomo, Francesca Bagnulo, Stefania Peluso, Luigi Carbone, Francesca Di Rella, Giuseppe De Placido, Filippo Maria Ubaldi, Ilpo Huhtaniemi, Carlo Alviggi, Carlo Alviggi   +11 more
doaj   +1 more source