Results 161 to 170 of about 45,803 (309)

Pancreatic Islet Cell Crosstalk: Insight Into α-/β-Cell Compensatory Mechanisms. [PDF]

Compr Physiol
Benáková Š, Holendová B, Dolenšek J, Křivonosková M, Stožer A, Plecitá-Hlavatá L.   +5 more
europepmc   +1 more source

Metabolic Dysfunction‐Associated Steatotic Liver Disease and Obesity: Pathogenesis, Diagnostics, Risk Stratification, and Therapeutic Approach

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Metabolic dysfunction‐associated steatotic liver disease (MASLD) has emerged as the most prevalent chronic liver disease worldwide, closely linked to the global rising incidence of obesity and metabolic syndrome. This review synthesizes current evidence on the pathogenesis, gut–liver axis, and multidisciplinary management of MASLD within the ...
Beom Kyung Kim
wiley   +1 more source

Metabolic Dysfunction-Associated Steatotic Liver Disease and Incretin Receptor Agonists: A Metabolic Approach to Halting Liver Disease Progression. [PDF]

Medicina (Kaunas)
Abenavoli L, Loricchio AG, Lopez I, Morano D, Ismaiel A, Dumitrascu DL, Luzza F.   +6 more
europepmc   +1 more source

Glucagon receptor family in GtoPdb v.2025.3

The glucagon family of receptors (nomenclature as agreed by the NC-IUPHAR Subcommittee on the Glucagon receptor family [170]) are activated by the endogenous peptide (27-44 aa) hormones glucagon, glucagon-like peptide 1, glucagon-like peptide 2, glucose ...
Miller, Laurence J., Göke, Burkhard, Mayo, Kelly E., Chan, Susan L., Drucker, Daniel J., Delagrange, Philippe, Hills, Rebecca, Salvatori, Roberto, Bataille, Dominique, Thorens, Bernard   +9 more
core   +1 more source

Alpha-cell glucagon is essential for maintaining β-cell function and identity in adult mice. [PDF]

J Biol Chem
Prasadan K, Saleh M, Thomas M, Al Abyad O, Shiota C, Molitoris J, Zhang T, Sehrawat A, Tariq M, Rajasundaram D, King S, Kalsi R, Xiao X, Piganelli J, Esni F, Gittes GK.   +15 more
europepmc   +1 more source

Recent advances in incretin biology and therapeutics: From glucose-dependent insulinotropic polypeptide reappraisal to next-generation agonists. [PDF]

J Diabetes Investig
Kubota S, Seino Y, Yabe D.
europepmc   +1 more source

Hypothalamus-liver talks: whispers in the language of metabolism. [PDF]

Rev Endocr Metab Disord
Ferreira V, Fernández-González I, Vattathara JJ, Rodríguez-Díaz A, Fernández-Sanmartín P, Diéguez C.   +5 more
europepmc   +1 more source

Glucagon receptor signalling – backwards and forwards [PDF]

Expert Opinion on Investigational Drugs, 2018
Tongzhi, Wu, Christopher K, Rayner, Chinmay S, Marathe, Karen L, Jones, Michael, Horowitz   +4 more
openaire   +2 more sources

Expression and functional activity of glucagon, glucagon-like peptide I, and glucose-dependent insulinotropic peptide receptors in rat pancreatic islet cells

, 1996
Rat pancreatic alpha- and beta-cells are critically dependent on hormonal signals generating cyclic AMP (cAMP) as a synergistic messenger for nutrient-induced hormone release, Several peptides of the glucagon-secretin family have been proposed as ...
Thorens, B, Schuit, Frans, Pipeleers, Daniel, Heimberg, H, Moens, Karen, Huypens, P, Ling, ZD, Gremlich, S, Flamez, Daisy, Quartier, E   +9 more
core  

High‐Fat Diet Exacerbates Neuropathology in a Transgenic Mouse Model of Multiple System Atrophy

Movement Disorders, EarlyView.
Abstract Background Multiple system atrophy (MSA) is a rare and devastating neurodegenerative disorder. Accumulating clinical and preclinical evidence suggests that diabetes and insulin resistance may adversely influence MSA pathophysiology. Objective We investigated the potential association between diabetes, impaired glucose homeostasis, and MSA ...
Marie‐Laure Arotcarena, Anna Delamarre, Miguel Lopez‐Cuina, Hugo Martin, Elio Balpe, Xavier Fioramonti, Erwan Bezard, Wassilios G. Meissner   +7 more
wiley   +1 more source