Results 131 to 140 of about 618,319 (304)
World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.The alpha and beta diversity of the nasal microbiome differed among children with allergic rhinitis (AR), nonallergic rhinitis (NAR), and healthy controls (HCs). Compared to HC, AR had more Escherichia‐Shigella, Negativicoccus, and Campylobacter, while NAR had more Dolosigranulum and fewer Enterobacteriaceae.
Kantima Kanchanapoomi +6 more
wiley +1 more source
Molecular Determinant Underlying Selective Coupling of Primary G‐Protein by Class A GPCRs
Advanced ScienceG‐protein‐coupled receptors (GPCRs) transmit downstream signals predominantly via G‐protein pathways. However, the conformational basis of selective coupling of primary G‐protein remains elusive.
Qingya Shen +16 more
doaj +1 more source
World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.ABSTRACT Objective Budesonide is a corticosteroid with unique pharmacokinetic and pharmacodynamic properties that has been a frontline treatment for patients with allergic rhinitis (AR) and chronic rhinosinusitis (CRS) since the 1990s. As research on budesonide continues to produce new insights, our aim was to synthesize recent investigations and ...
David W. Kennedy +2 more
wiley +1 more source
Use of antihistamines in a physician's clinical practice
Терапевтический архив, 2014 Histamine that belongs to one of the most important mediators involved in the regulation of the body's vital functions plays a great role in the pathogenesis of different diseases.
L V Luss
doaj
Histamine inhibits activation of human neutrophils and HL-60 leukemic cells via H_2-receptors [PDF]
, 1989 Schultz, Günther +3 more
core +1 more source
Co-localization of Histamine and eGFP in the Central Nervous System from pHdc-5’-UTR-eGFP Transformants of Drosophila melanogaster [PDF]
, 2009 Histamine is a biogenic amine synthesized by the enzyme histidine decarboxylase (Hdc) and used as a neurotransmitter in the central nervous system of Drosophila melanogaster.
Ervin, Wendi-Jo L.
core
The Journal of Dermatology, EarlyView.ABSTRACT Physical urticaria is a subtype of chronic inducible urticaria characterized by wheals and/or angioedema triggered by physical stimuli. We report a refractory case of combined localized heat urticaria, delayed solar urticaria, and symptomatic dermographism in a 16‐year‐old girl.
Shuta Yoshitani +2 more
wiley +1 more source
Novel Bispecific Engagers Targeting the CεmX Domain of mIgE‐Expressing Cells
Allergy, EarlyView.We developed bispecific TCE & NKCE targeting the CεmX domain of mIgE to eliminate IgE‐producing cells. Both constructs demonstrated potent, specific, dose‐dependent cytotoxicity and selective immune activation in vitro. These results highlight their promise as off‐the‐shelf, potentially curative therapeutics for IgE‐associated allergic diseases ...
Constantin Möller +16 more
wiley +1 more source
Identification of histamine receptors in the canine gastrointestinal tract [PDF]
, 2016 The role of histamine in chronic gastrointestinal diseases has been increasingly recognized in humans, but the role of histamine in the canine gastrointestinal tract has not been thoroughly investigated.
Sullivant, Alyssa Martin
core
The Evolution of Sesame Seed Allergy Over Time
Allergy, EarlyView.This study analyzes the natural history of sesame over time and the changes in biomarkers between sesame allergic and sesame sensitised but tolerant children. The period prevalence of sesame allergy increased from 0.5% between 12 and 36 m to 1.5% between 7 and 12 y children in the EAT‐On study with 10 children developing new sesame allergy. Sesame‐sIgE
Ru‐Xin Foong +14 more
wiley +1 more source