Release of histamine by H2-receptor antagonists [PDF]
The Lancet, 1987 letter
Dietz, W. +2 more
core +7 more sources
Physiological implications of biased signaling at histamine H2 receptors. [PDF]
Frontiers in Pharmacology, 2015 Histamine mediates numerous functions acting through its four receptor subtypes all belonging to the large family of seven transmembrane G-protein coupled receptors (GPCRs).
Natalia eAlonso +14 more
doaj +3 more sources
The Impact of H1–H4 Receptor Antagonists on the Levels of Selected Oxidative Stress Markers in Liver and Muscle Tissue in an Animal Model of Colitis [PDF]
PharmaceuticalsBackground/Objectives: The global prevalence and incidence of inflammatory bowel diseases have risen in the past two decades. Among them, Crohn’s disease and ulcerative colitis are still challenging to treat due to vascular and proliferative alterations.
Bartosz Bogielski +16 more
doaj +2 more sources
Modulation of vestibular function and receptor expression by experimental hypergravity in a rat model [PDF]
Scientific ReportsMotion sickness develops because of a mismatch or conflict between the information gathered from the visual input, somatosensory input, and the vestibular system. Altered gravity can cause motion sickness while traveling in space. In this study, we aimed
Jin Sil Choi +4 more
doaj +2 more sources
In Vivo Effect of a Synthetic Amniotic Fluid on Fetal Lung and Gastrointestinal Tract: A Pre-Clinical Rodent Model. [PDF]
Prenat DiagnABSTRACT Objective Amnioinfusions in anhydramnios aim to promote fetal lung development, but currently used fluids (Normal Saline [NS], Lactated Ringer's [LR]) fail to mimic the intrauterine environment and increase reactive oxygen species (ROS). We developed a synthetic amniotic fluid (Amnio‐well, AW) designed to reduce intrauterine ROS.
Forde B, Finoti S, Oria M, Peiro JL.
europepmc +2 more sources
The Roles of Cardiovascular H2-Histamine Receptors Under Normal and Pathophysiological Conditions
Frontiers in Pharmacology, 2021 This review addresses pharmacological, structural and functional relationships among H2-histamine receptors and H1-histamine receptors in the mammalian heart.
Joachim Neumann +4 more
doaj +1 more source
Histamine can be Formed and Degraded in the Human and Mouse Heart
Frontiers in Pharmacology, 2021 Histamine is metabolized by several enzymes in vitro and in vivo. The relevance of this metabolism in the mammalian heart in vivo is unclear. However, histamine can exert positive inotropic effects (PIE) and positive chronotropic effects (PCE) in humans ...
Joachim Neumann +12 more
doaj +1 more source
Correlation of Histamine Receptors and Adrenergic Receptor in Broilers Appetite [PDF]
Archives of Razi Institute, 2022 The current study was conducted to investigate the interaction between the central adrenergic and histaminergic systems and the broiler chick’s feed intake.
M Daneshvar +3 more
doaj +1 more source
Changes in Histamine Receptors (H1, H2, and H3) Expression in Rat Medial Vestibular Nucleus and Flocculus after Unilateral Labyrinthectomy: Histamine Receptors in Vestibular Compensation. [PDF]
PLoS ONE, 2013 Vestibular compensation is the process of behavioral recovery following peripheral vestibular lesion. In clinics, the histaminergic medicine is the most widely prescribed for the treatment of vertigo and motion sickness, however, the molecular mechanisms
Liuqing Zhou +6 more
doaj +1 more source
Alterations in histamine responses between juvenile and adult urinary bladder urothelium, lamina propria and detrusor tissues [PDF]
, 2020 Inflammatory mediators may have a role in various lower urinary tract disorders. Histamine is known to induce significant increases in both the tension and frequency of spontaneous phasic contractions in both urothelium with lamina propria (U&LP) and
Chess-Williams, Russ +2 more
core +1 more source