Results 31 to 40 of about 784,733 (223)

Ergotamine Stimulates Human 5-HT4-Serotonin Receptors and Human H2-Histamine Receptors in the Heart

, 2023
Ergotamine (2′-methyl-5′α-benzyl-12′-hydroxy-3′,6′,18-trioxoergotaman) is a tryptamine-related alkaloid from the fungus Claviceps purpurea. Ergotamine is used to treat migraine.
Uwe Kirchhefer, Joachim Neumann, Hannes Jacob, Britt Hofmann, Christian Höhm, Rebecca Schwarz, Pauline Braekow, Ulrich Gergs   +7 more
core   +1 more source

Histamine and migraine revisited: mechanisms and possible drug targets

The Journal of Headache and Pain, 2019
Objective To review the existing literature on histamine and migraine with a focus on the molecule, its receptors, its use in inducing migraine, and antihistamines in the treatment of migraine. Background Histamine has been known to cause a vascular type
Jacob Worm, Katrine Falkenberg, Jes Olesen   +2 more
doaj   +1 more source

Plasticity of histamine H3 receptor expression and binding in the vestibular nuclei after labyrinthectomy in rat [PDF]

, 2004
Background: In rat, deafferentation of one labyrinth (unilateral labyrinthectomy) results in a characteristic syndrome of ocular and motor postural disorders (e.g., barrel rotation, circling behavior, and spontaneous nystagmus). Behavioral recovery (e.g.,
Panula, Pertti, Lozada, Adrian F., Kaj Karlstedt, Karlstedt, Kaj, Aarnisalo, Antti A., Stark, Holger, Adrian F Lozada, Pertti Panula, Antti A Aarnisalo, Holger Stark   +9 more
core   +1 more source

Physiological implications of biased signaling at histamine H2 receptors.

Frontiers in Pharmacology, 2015
Histamine mediates numerous functions acting through its four receptor subtypes all belonging to the large family of seven transmembrane G-protein coupled receptors (GPCRs).
Natalia eAlonso, Natalia eAlonso, Carlos Daniel Zappia, Carlos Daniel Zappia, Maia eCabrera, Maia eCabrera, Carlos Alberto Davio, Carlos Alberto Davio, Carlos Alberto Davio, Carina eShayo, Carina eShayo, Federico eMonczor, Federico eMonczor, Natalia Cristina Fernandez, Natalia Cristina Fernandez   +14 more
doaj   +1 more source

Identification and characterization of ZEL-H16 as a novel agonist of the histamine H3 receptor. [PDF]

PLoS ONE, 2012
The histamine H3 receptor (H3R) has been recognized as a promising target for the treatment of various central and peripheral nervous system diseases.
Ying Shi, Rong Sheng, Tingting Zhong, Yu Xu, Xiaopan Chen, Dong Yang, Yi Sun, Fenyan Yang, Yongzhou Hu, Naiming Zhou   +9 more
doaj   +1 more source

Molecular analysis of the histamine H3-receptor [PDF]

, 2010
The histamine H3 receptor (H3R) is a biogenic amine receptor that belongs to family I of G protein-coupled receptors (GPCRs). During the past two decades, the H3R has gained much interest in academia and industry.
Schnell, David
core   +1 more source

Predictors of Response to Oral Medications and Low-Histamine Diet in Patients with Chronic Urticaria

Journal of Immunology Research, 2022
Background. Chronic urticaria (CU) is comprised of diverse phenotypes, and thus, a shift towards a precision medical approach is warranted in its management. Methods. This study enrolled 78 patients with CU.
Hui-Ling Chiang, Chen-Hung Chen, Malcolm Koo, Tzung-Yi Tsai, Cheng-Han Wu   +4 more
doaj   +1 more source

Mast Cells May Differentially Regulate Growth of Lymphoid Neoplasms by Opposite Modulation of Histamine Receptors

Frontiers in Oncology, 2019
Cancer microenvironment is complex and consists of various immune cells. There is evidence for mast cell (MC) infiltration of tumors, but their role thereof is poorly understood.
Sandeep Paudel, Deeksha Mehtani, Niti Puri   +2 more
doaj   +1 more source

H1 and H2 Histamine Receptors Are Absent on Langerhans Cells and Present on Dermal Dendritic Cells [PDF]

, 2003
Human monocyte-derived dendritic cells (MoDC) have both histamine H1 and H2 receptors and can induce CD86 expression by histamine. Nevertheless, it has not been reported whether human epidermal Langerhans cells (LC) have histamine receptors or not.
Aiba, Setsuya, Nakagawa, Satoshi, Setsuya Aiba, Tagami, Hachiro, Tomoyuki Ohtani, Satoshi Nakagawa, Mizuashi, Masato, Mollah, Zia U.A., Hachiro Tagami, Ohtani, Tomoyuki, Masato Mizuashi, Zia U.A. Mollah   +11 more
core   +1 more source

Hippocampal histamine receptors and conflictive exploration in the rat: studies using the elevated asymmetric plus-maze

Brazilian Journal of Medical and Biological Research, 1997
The possible role of histamine receptors in the hippocampal formation on the exploratory motivation and emotionality of the rat was studied. An elevated asymmetric plus-maze composed of 4 different arms (no walls, single high wall, high and low walls and
M.B. Ruarte, A.G. Orofino, E.O. Alvarez
doaj   +1 more source