Results 191 to 200 of about 321,989 (218)

Do Oxidative Stress-Modified Exosomes Contribute to Infertility in Endometriosis? [PDF]

Int J Mol Sci
Voros C, Chatzinikolaou F, Papadimas G, Papapanagiotou I, Zagorianakou N, Gunes AC, Karpouzos A, Bananis K, Tsimpoukelis C, Daskalaki MA, Makrydimas S, Pikrides I, Thomakos N, Antsaklis P, Loutradis D, Daskalakis G.   +15 more
europepmc   +1 more source

Crosstalk Between CTSB+ Glioblastoma Cells and S100A10+ Macrophages: A Self‐Reinforcing Circuit Promotes Immune Evasion and Limits Response to Immunotherapy

Advanced Science, EarlyView.
In glioblastoma, M2‐polarized macrophages secrete IL‐6, which activates STAT3 signaling in tumor cells to upregulate CTSB. Tumor‐derived CTSB binds the C‐terminus of macrophage S100A10, reinforcing M2 polarization and further IL‐6 secretion, thereby establishing a feedforward IL‐6/STAT3/CTSB/S100A10 loop. This cascade drives tumor growth, invasion, and
Hao Zhang, Nan Zhang, Xisong Liang, Jie Wen, Ziyu Dai, Wantao Wu, Shuyu Li, Songshan Feng, Zaoqu Liu, Zhiwei Xia, Peng Luo, Quan Cheng   +11 more
wiley   +1 more source

Therapeutic Opportunities for Macrophage Targeted Nanomedicine in Diabetes Mellitus. [PDF]

Int J Nanomedicine
Luo J, Hou Y, Lin Y, Zhang X, Zhang W, Sun K.   +5 more
europepmc   +1 more source

Literature Review: Recent Therapeutic Advances in The Management of Prurigo Nodularis: From Conventional Therapy to Biologics and Targeted Small-Molecule Agents. [PDF]

Clin Cosmet Investig Dermatol
Avriyanti E, Larasati R, Rengasamy S, Hidayah RMN, Tsaqilah L, Pangastuti M, Maharani RH.   +6 more
europepmc   +1 more source

Interleukin-15-armored ALPPL2 CAR T cells demonstrate robust preclinical efficacy for solid tumors. [PDF]

Mol Ther Oncol
Liu J, Zhang N, An Z, Heczey A.
europepmc   +1 more source

Neural-immune-cardiovascular axis: from mechanistic crosstalk to therapeutic targets in cardiovascular disease. [PDF]

Front Immunol
Cheng J, Gao S, Zhang H, Gao W, Mei Z, Liu X, Gao J, Guo C, An G.   +8 more
europepmc   +1 more source

Estradiol-17β, a key embryonic signal, regulates gene expression and cellular functions in the porcine trophoblast. [PDF]

Biol Reprod
Goryszewska-Szczurek E, Waclawik A.
europepmc   +1 more source

Impact of Aggregatibacter actinomycetemcomitans on inflammasome regulation and epigenetic changes in grade C periodontitis. [PDF]

Clin Oral Investig
Reis AA, Paz HES, Sacramento CM, Silvério KG, Sallum EA, Freitas Monteiro M, Casarin RCV, Stolf CS.   +7 more
europepmc   +1 more source

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Interleukin-6 Signaling and Anti-Interleukin-6 Therapeutics in Cardiovascular Disease

Circulation Research, 2021

exaly  

Biology and therapeutic potential of interleukin-10

Journal of Experimental Medicine, 2020
Anne O'Garra, Margarida Saraiva, Paulo Vieira   +2 more
exaly