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Interleukin-2 and the interleukin-2 receptor complex

1990
Abstract Interleukin 2 (IL-2), originally designated as a T cell growth factor, is a glycoprotein with a molecular weight of 15.4 kD. The genes encoding the human, murine, and bovine IL-2 were cloned, their nucleotide sequences determined, and corresponding amino acid sequences deduced.-3 Human IL-2 consists of 133 amino acids and ...
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Soluble interleukin-2 receptor in cancer

Frontiers in Bioscience, 2004
Levels of serum sIL-2R (soluble interleukin-2 receptor) reflect the total amount of activated T lymphocytes in tumor infiltrating lymphocytes of cancer tissues and metastatic organs, because a part of alpha-chain of IL-2R is released into the bloodstream on the attachment of IL-2 (interleukin-2) to its specific IL-2R membrane.
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Sharing of the interleukin-2 (IL-2) receptor gamma chain between receptors for IL-2 and IL-4.

Science, 1993
M. Kondo   +6 more
semanticscholar   +1 more source

Circulating soluble tumor necrosis factor receptors, interleukin‐2 receptors, tumor necrosis factor α, and interleukin‐6 levels in rheumatoid arthritis.

, 1993
P. Barrera   +9 more
semanticscholar   +1 more source

The Multisubunit Interleukin‐2 Receptor

Annals of the New York Academy of Sciences, 1990
W J, Leonard, J R, Gnarra, M, Sharon
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Corticosteroid-interleukin 2 interactions: inhibition of binding of interleukin 2 to interleukin 2 receptors.

Clinical and experimental immunology, 1987
PHA activated human peripheral blood mononuclear cells (MNC) were incubated with human interleukin 2 (IL-2) in the absence or in the presence of 10(-6)-10(-9) M hydrocortisone (HC). HC suppressed the proliferative response of the activated MNC to highly purified human leucocyte IL-2 in a dose dependent manner.
H J, Horst, H D, Flad
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