Intrathymic laminin-mediated interactions: role in T cell migration and development
Frontiers in Immunology, 2015 Intrathymic T cell differentiation is a key process for the development and maintenance of cell-mediated immunity, and occurs concomitantly to highly regulated migratory events. We have proposed a multivectorial model for describing intrathymic thymocyte
Wilson eSavino +4 more
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Laminin receptor 37/67LR regulates adhesion and proliferation of normal human intestinal epithelial cells. [PDF]
PLoS ONE, 2013 Interactions between the cell basal membrane domain and the basement membrane are involved in several cell functions including proliferation, migration and differentiation.
Taoufik Khalfaoui +6 more
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Ultrastructure of acetylcholine receptor aggregates parallels mechanisms of aggregation
BMC Neuroscience, 2001 Background Acetylcholine receptors become aggregated at the developing neuromuscular synapse shortly after contact by a motorneuron in one of the earliest manifestations of synaptic development. While a major physiological signal for receptor aggregation
Lee Lara K +2 more
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Role of laminin and cognate receptors in cholangiocarcinoma cell migration
Cell Adhesion & Migration, 2021 Extensive desmoplasia in cholangiocarcinoma (CCA) is associated with tumor aggressiveness, indicating a need for further understanding of CCA cell–matrix interaction.
Kittiya Islam +4 more
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A novel monoclonal antibody to human laminin α5 chain strongly inhibits integrin-mediated cell adhesion and migration on laminins 511 and 521. [PDF]
PLoS ONE, 2013 Laminins, a large family of αβγ heterotrimeric proteins mainly found in basement membranes, are strong promoters of adhesion and migration of multiple cell types, such as tumor and immune cells, via several integrin receptors.
Zenebech Wondimu +8 more
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Skeletal Muscle, 2017 Background The hepatocyte growth factor (HGF) is required for the activation of muscle progenitor cells called satellite cells (SC), plays a role in the migration of proliferating SC (myoblasts), and is present as a soluble factor during muscle ...
Mariela Natacha González +6 more
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Receptors that bind to PEDF and their therapeutic roles in retinal diseases
Frontiers in Endocrinology, 2023 Retinal neovascular, neurodegenerative, and inflammatory diseases represented by diabetic retinopathy are the main types of blinding eye disorders that continually cause the increased burden worldwide.
Manhong Xu +3 more
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Skeletal muscle laminin and MDC1A: pathogenesis and treatment strategies
Skeletal Muscle, 2011 Laminin-211 is a cell-adhesion molecule that is strongly expressed in the basement membrane of skeletal muscle. By binding to the cell surface receptors dystroglycan and integrin α7β1, laminin-211 is believed to protect the muscle fiber from damage under
Gawlik Kinga I, Durbeej Madeleine
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Gene Expression in Amnion-Derived Cells Cultured on Recombinant Laminin 332—A Preliminary Study
Frontiers in Medicine, 2021 Human amniotic cells (hAC) exhibit characteristics of undifferentiated cells and immunomodulatory properties. Recognition of the relationship between amniotic cells and components of the extracellular matrix is an important condition for their ex vivo ...
Katarzyna Skowron-Kandzia +5 more
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The impact of genetic manipulation of laminin and integrins at the blood–brain barrier
Fluids and Barriers of the CNS, 2022 Blood vessels in the central nervous system (CNS) are unique in having high electrical resistance and low permeability, which creates a selective barrier protecting sensitive neural cells within the CNS from potentially harmful components in the blood ...
Sebok K. Halder +2 more
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