Results 1 to 10 of about 100,377 (261)
Integrins in cancer: insights into mechanisms and therapeutic potential [PDF]
Cell Communication and SignalingIntegrins are transmembrane glycoproteins that act as essential adhesion receptors, allowing cells to communicate with the extracellular matrix (ECM).
Parth Agarwal +4 more
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Integrins mediate symbiont-specific uptake in cnidarian larvae [PDF]
EMBO ReportsEndosymbiosis between dinoflagellate algae and cnidaria is fundamental for coral reef health. Appropriate symbiont selection is required for sufficient host nutrient acquisition and could be tailored to increase cnidarian stress tolerance.
Victor A S Jones +10 more
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Above the Matrix: Functional Roles for Apically Localized Integrins
Frontiers in Cell and Developmental Biology, 2021 Integrins are transmembrane proteins that are most typically thought of as integrating adhesion to the extracellular matrix with intracellular signaling and cell regulation.
Raven J. Peterson +2 more
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Integrins in human hepatocellular carcinoma tumorigenesis and therapy
Chinese Medical Journal, 2023 . Integrins are a family of transmembrane receptors that connect the extracellular matrix and actin skeleton, which mediate cell adhesion, migration, signal transduction, and gene transcription.
Qiong Gao +3 more
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Cell and Tissue Research, 2009 Integrins are cell adhesion receptors that are evolutionary old and that play important roles during developmental and pathological processes. The integrin family is composed of 24 alphabeta heterodimeric members that mediate the attachment of cells to the extracellular matrix (ECM) but that also take part in specialized cell-cell interactions.
Barczyk, Malgorzata +2 more
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Molecular Therapy: Oncolytics, 2022 High-grade gliomas (HGGs) are lethal central nervous system tumors that spread quickly through the brain, making treatment challenging. Integrins are transmembrane receptors that mediate cell-extracellular matrix (ECM) interactions, cellular adhesion ...
Kimberly Ann Rivera-Caraballo +4 more
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Nascent Adhesion Clustering: Integrin-Integrin and Integrin-Substrate Interactions [PDF]
Biophysica, 2022 Nascent adhesions (NAs) are a general precursor to the formation of focal adhesions (FAs) that provide a fundamental mechanism for cell adhesion that is, in turn, involved in cell proliferation, migration, and mechanotransduction. Nascent adhesions form when cells come into contact with substrates at all rigidities and generally involve the clustering ...
Kuanpo Lin, Robert J. Asaro
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Integrins in the Immunity of Insects: A Review
Frontiers in Immunology, 2022 Integrins are a large group of cell-surface proteins that are classified as transmembrane proteins. Integrins are classified into different types based on sequence variations, leading to structural and functional diversity.
Saima Kausar +8 more
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Frontiers in Immunology, 2020 Studies on invertebrate immune receptors can provide insights into characteristics specific to innate immune system. Here, eight α and three β integrins are identified from an invertebrate, the Pacific oyster Crassostrea gigas, and their possible immune ...
Zhao Lv +18 more
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