Results 21 to 30 of about 101,656 (264)
Role of integrins in wound repair and its periodontal implications
Journal of Oral Biology and Craniofacial Research, 2018 Wound healing in human periodontium is a complex process which involves both cell-cell and cell-matrix interactions. Integrins play a major role in regulation of these cell-cell, cell-matrix interaction. Wound healing involves two major events i.e.
Harpal Jakhu +2 more
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Irisin supports integrin-mediated cell adhesion of lymphocytes
Biochemistry and Biophysics Reports, 2021 Irisin, a myokine released from skeletal muscle, has recently been found to act as a ligand for the integrins αVβ5, αVβ1, and α5β1 expressed on mesenchymal cells, thereby playing an important role in the metabolic remodeling of the bone, skeletal muscle ...
Phyoe Kyawe Myint +8 more
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F1000Research, 2017 While integrins were originally discovered as cell adhesion receptors, recent studies have reinforced the concept that integrins have central roles in cancer that extend far beyond controlling cell adhesion and migration.
Whitney Longmate, C Michael DiPersio
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Integrins, cancer and snake toxins (mini-review)
Journal of Venomous Animals and Toxins including Tropical Diseases, 2005 Integrins encompass a family of transmembrane heterodimeric proteins of adhesion that maintain cells attached to other cells and to the extracellular matrix (ECM).
G. Rádis-Baptista
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BMB Reports, 2014 Integrin-mediated cell adhesion is important for development, immune responses, hemostasis and wound healing. Integrins also function as signal transducing receptors that can control intracellular pathways that regulate cell survival, proliferation, and cell fate.
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Integrins and the Myocardium [PDF]
Circulation Research, 2001 Abstract —Extracellular matrix provides a structural, chemical, and mechanical substrate that is essential in cardiac development, growth, and responses to pathophysiological signals. Transmembrane receptors termed integrins provide a dynamic interaction of environmental cues and intracellular events.
R S, Ross, T K, Borg
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Integrin activation states and eosinophil recruitment in asthma
Frontiers in Pharmacology, 2013 Eosinophil arrest and recruitment to the airway in asthma are mediated, at least in part, by integrins. Eosinophils express α4β1, α6β1, αLβ2, αMβ2, αXβ2, αDβ2, and α4β7 integrins, which interact with counter-receptors on other cells or ligands in the ...
Mats W Johansson, Deane F Mosher
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Integrin signaling in cancer: bidirectional mechanisms and therapeutic opportunities
Cell Communication and Signaling, 2023 Integrins are transmembrane receptors that possess distinct ligand-binding specificities in the extracellular domain and signaling properties in the cytoplasmic domain.
Siyi Li +4 more
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Cells, 2022 Smooth muscle cells (SMCs), present in the media layer of blood vessels, are crucial in maintaining vascular homeostasis. Upon vascular injury, SMCs show a high degree of plasticity, undergo a change from a “contractile” to a “synthetic” phenotype, and ...
Manish Jain, Anil K. Chauhan
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Integrins in Mechanotransduction [PDF]
Journal of Biological Chemistry, 2004 Mechanical forces are crucial to the regulation of cell and tissue morphology and function. At the cellular level, forces influence cytoskeletal organization, gene expression, proliferation, and survival. Integrin-mediated adhesions are intrinsically mechanosensitive and a large body of data implicates integrins in sensing mechanical forces.
Akira, Katsumi +3 more
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