Results 141 to 150 of about 632,116 (307)
The role of leptin as a biochemical marker in health and disease
, 2023 Leptin is a hormone primarily produced by adipose tissue (fat cells) and is critical in regulating energy balance and metabolism (Martinez-Sanchez 2020; Abella et al. 2017).
Karimkhani,H.
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Medicine Bulletin, EarlyView.ABSTRACT β‐Aminoisobutyric acid (BAIBA) is an exercise‐responsive myokine/metabolite released by skeletal muscle and has attracted increasing interest as a potential exercise mimetic and therapeutic candidate in preclinical research. BAIBA acts locally in skeletal muscle and can also reach distal organs through the circulation, contributing to the ...
Hao‐Zhe Wang +5 more
wiley +1 more source
Possible pharmacological role of Leptin medication in pregnancy
, 2021 Through this Thesis I tried to explore the multiple options of using Leptin as a medical tool, I chose to focus on the role of Leptin as a key factor, whose deficiency may impair pregnancy processes, and chose to do my best in arising the awareness of ...
Botchan, Shay Nohar
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Proteins: Structure, Function, and Bioinformatics, EarlyView.ABSTRACT Protein Tyrosine Phosphatases (PTPs) regulate cellular signaling by balancing phosphotyrosine levels through a conserved WPD‐loop that switches between open (inactive) and closed (active) conformations. While this conformational change is crucial for catalysis, the structural factors governing this motion remain poorly understood.
Colin L. Welsh, Lalima K. Madan
wiley +1 more source
Phytotherapy Research, EarlyView.ABSTRACT Obesity is a major risk factor for type 2 diabetes. Some traditional Chinese medicine (TCM) compounds can improve obesity by increasing energy consumption. This study aimed to identify and verify TCM compounds that promote adipose thermogenesis to alleviate obesity via transcriptomic analysis, molecular docking, network pharmacology, and ...
Jing Li +6 more
wiley +1 more source
Control of food intake via leptin receptors in the hypothalamus
, 2000 Food intake is regulated via neural circuits located in the hypothalamus. During the past decade our knowledge on the specific mediators and neuronal networks that regulate food intake and body weight has increased dramatically. An important contribution
Björn Meister, Meister, B,
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Environmental Toxicology, EarlyView.ABSTRACT Pancreatic cancer is the fourth leading cause of cancer deaths in the US and predicted to rise to second by 2030. Several risk factors have been identified as potential contributors to pancreatic cancer development including lifestyle factors and long‐term exposure to occupational and environmental carcinogens.
Barbara A. Hocevar, Lisa M. Kamendulis
wiley +1 more source
AN ECONOMIC ANALYSIS OF GENETIC INFORMATION: LEPTIN GENOTYPING IN FED CATTLE [PDF]
The use of genetic knowledge is widespread in crop production but is just recently being utilized in livestock production. This study investigates the economic value to feedlots of a polymorphism in the bovine leptin gene.
Bullinger, Jared R. +4 more
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Mechanisms underlying leptininduced cardioprotection [PDF]
, 2010 BACKGROUND: The tissue damage resulting from myocardial ischaemia/reperfusion (I/R) leads to a large proportion of the deaths in the developed world.
Dixon, R.A.
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Environmental Toxicology, EarlyView.ABSTRACT Microplastics (MPs) have been identified as major environmental contaminants that can affect organisms directly and act as carriers of particles and chemical additives, thereby aggravating endocrine networks that coordinate metabolic homeostasis.
Sunday Amos Onikanni +10 more
wiley +1 more source