Results 241 to 250 of about 94,971 (311)

Obesity Reduces Endometrial Receptivity by Downregulating the Ob-Rb/STAT-3 Signaling Pathway in Women and Female Mice. [PDF]

J Endocr Soc
Tang F, Wang W, Wang L, Wang Y, Xie P, Fang Y, Guo P, Li C, Cao Y, Wei Z, He Y.   +10 more
europepmc   +1 more source

Impaired angiogenesis in gestational diabetes is linked to succinate/SUCNR1 axis dysregulation in late gestation

The Journal of Physiology, EarlyView.
Abstract figure legend Gestational Diabetes Mellitus (GDM) impacts on succinate metabolism and angiogenesis in the umbilical cord endothelium. (Left Panel) Succinate levels increase in both maternal and fetal circulation at delivery, with higher concentrations observed in GDM pregnancies compared to controls during late gestation.
Sergiy Klid, Francisco Algaba‐Chueca, Elsa Maymó‐Masip, Mónica Ballesteros, Montse Inglés, Albert Guarque, Nerea Vilanova‐Ricart, Ariadna Prats, Azra Kulovic‐Sissawo, Elisa Weiss, Ursula Hiden, Joan Vendrell, Sonia Fernández‐Veledo, Ana Megía   +13 more
wiley   +1 more source

Neural regulation of bone: from central neural circuits to peripheral innervation of the skeletal stem cell niche. [PDF]

Bone Res
Chen Z, Luo Z, Greenblatt MB, Wu Z, Xu R.   +4 more
europepmc   +1 more source

Sex‐specific metabolic responses to glucagon receptor agonism and modulation of the FGF21‐glucagon axis in female mice

The Journal of Physiology, EarlyView.
Abstract figure legend Therapies targeting the glucagon receptor are being explored for obesity treatment, yet most preclinical studies remain male biased. In this study, Merrild and Johansen et al. show that in diet‐induced obese wild‐type mice a long‐acting glucagon analogue (LA‐Gcg) elicits sexually dimorphic effects on weight loss, food intake ...
Christoffer Merrild, Valdemar Brimnes Ingemann Johansen, Christoffer Clemmensen, Pablo Ranea‐Robles   +3 more
wiley   +1 more source

Amylin Revisited: A 5-Year Perspective on Its Emerging Role in the Treatment of Diabesity. [PDF]

J Obes Metab Syndr
Chung CW, Kim J.
europepmc   +1 more source

Wellness testing in blood donation: A framework for responsible innovation

Transfusion, EarlyView.
Jeremy W. Jacobs, Sheharyar Raza, Brian D. Adkins, Victoria Costa, David M. Chooljian, Garrett S. Booth   +5 more
wiley   +1 more source

Reduced cardiovascular mortality at moderate altitude: a putative role of physical activity and body mass

The Journal of Physiology, EarlyView.
Abstract figure legend Benefits of performing physical exercise at moderate altitude. At moderate altitude, increased resting metabolic rate and physical exertion promote physical fitness and exercise tolerance, whereas hypoxia suppresses appetite and elicits adaptations that increase tissue O2 delivery while augmenting O2‐independent ATP production ...
Robert T. Mallet, Johannes Burtscher, Hannes Gatterer, Katharina Hüfner, Samuel Verges, Tadej Debevec, Martin Burtscher   +6 more
wiley   +1 more source

Neurotrophic Control of Puberty: From Molecular Signaling to Disorders of Pubertal Timing. [PDF]

Curr Issues Mol Biol
Paparella R, Iafrate N, Lucibello R, Bei A, Bernabei I, Fiorentini C, Marchetti L, Pastore F, Maglione V, Niceta M, Fiore M, Venditti S, Pucarelli I, Tarani L.   +13 more
europepmc   +1 more source

Chronic attenuation of brain leptin signalling is associated with early metabolic dysfunction in lean rats

The Journal of Physiology, EarlyView.
Abstract figure legend Central leptin signalling blockade induces early metabolic dysfunction. Intracerebroventricular infusion of a leptin receptor antagonist (SLA) in rats disrupts hypothalamic leptin signalling, leading to reduced signal transducer and activator of transcription 3 (STAT3) activation, decreased Socs3 and Pomc expression, and ...
Cristina Pintado, Lorena Mazuecos, Óscar Gómez‐Torres, Beatriz Merino, Elena Casanueva‐Álvarez, Blanca Rubio, Emma Burgos‐Ramos, Sara Artigas‐Jerónimo, Eduardo Moltó, Inés María Ramos, Justa María Poveda, Germán Perdomo, Irene Cózar‐Castellano, Carmen Arribas, Ernesto Bernal‐Mizrachi, Antonio Andrés, Nilda Gallardo   +16 more
wiley   +1 more source

Leptin receptor rs1137101 polymorphism and altered leptin-sOb-R axis contribute to type 2 diabetes risk in Gujarat population. [PDF]

Front Endocrinol (Lausanne)
Parmar N, Rathwa N, Patel R, Pramanik Palit S, Patel N, Shetty S, Dwivedi M, Begum R, Ramachandran AV.   +8 more
europepmc   +1 more source