Results 271 to 280 of about 632,116 (307)

Localization of Leptin Binding Domain in the Leptin Receptor

Molecular Pharmacology, 1998
The leptin receptor is a member of the class I cytokine receptor family and is involved in the control of appetite and body weight. The predicted amino acid sequence of the extracellular region of the cloned leptin receptor differs from that of many other cytokine receptors in that it contains two homologous segments representing potential ligand ...
T M, Fong, R R, Huang, M R, Tota, C, Mao, T, Smith, J, Varnerin, V V, Karpitskiy, J E, Krause, L H, Van der Ploeg   +8 more
openaire   +2 more sources

Leptin, leptin soluble receptor and coronary atherosclerosis

Experimental and Clinical Endocrinology & Diabetes, 2007
AbstractBackground  The adipose tissue‐related hormone leptin plays an important role in the regulation of body weight. The associations of leptin and leptin soluble receptor (sOb‐R) with coronary artery disease (CAD) are not clear.Design  We measured leptin and sOb‐R in 543 consecutive patients (379 men, 164 women) referred for coronary angiography ...
G, Hoefle, C H, Saely, L, Risch, P, Rein, L, Koch, F, Schmid, S, Aczél, T, Marte, P, Langer, H, Drexel   +9 more
openaire   +2 more sources

Immunoassays for Leptin and Leptin Receptors

2006
Availability of methods for accurate and reproducible quantification of lepth in various biological fluids in humans and in animals has greatly facilitated research leading to the understanding of its role in various physiological and pathophysiological conditions. Immunoassay techniques provide a simple and robust tool for measurement of biomolecules.
openaire   +1 more source

Plasma leptin levels in pigs with different leptin and leptin receptor genotypes

Journal of Animal Breeding and Genetics, 2008
SummaryA C3469T mutation at exon 3 of the pig leptin (Lep) gene has been genotyped in diverse pig breeds yielding controversial results with regard to its association with growth, fatness and carcass traits. A similar situation has been reported for a HpaII restriction fragment length polymorphism (RFLP) in the pig leptin receptor (Lepr) gene, where ...
Amills, Marcel, Villalba, D., Tor, M., Mercadé, Anna, Gallardo, David, Cabrera, Betlem, Jiménez, N., Noguera, José L., Sánchez, Armand, Estany, J.   +9 more
openaire   +3 more sources

The involvement of leptin in humans revealed by mutations in leptin and leptin receptor genes

Trends in Pharmacological Sciences, 1999
Support for our work comes mostly from the Centre National de la Recherche Scientifique, the Institut National de la Sante et de la Recherche Medicale, the University of Paris VII, the Ministry for Research and Technology. We are also grateful for help from the Ligue Nationale contre le Cancer, the Fondation pour la Recherche Medicale Francaise and ...
A D, Strosberg, T, Issad
openaire   +2 more sources

[Leptin Receptor].

Nihon rinsho. Japanese journal of clinical medicine, 1998
Leptin is a fat cell-derived satiety factor that regulates food intake and energy expenditure. Its effects are mediated by interactions with the leptin receptor (Ob-R) that is alternatively spliced to encode at least five isoforms(a-e), which are distributed in a wide range of tissues including the hypothalamus.
K, Takaya, Y, Ogawa, H, Masuzaki, N, Matsuoka, K, Hosoda, K, Nakao   +5 more
openaire   +1 more source

Leptin and its receptor

Journal of Endocrinology, 1997
J L, Halaas, J M, Friedman
openaire   +2 more sources

Leptin and Obesity: Role and Clinical Implication

Frontiers in Endocrinology, 2021
Takashi Gojobori, Swati Arya, Esma Isenovic   +2 more
exaly  

Leptin and Leptin Receptor

2016
Lennart Zabeau, Frank Peelman, Jan Tavernier   +2 more
openaire   +1 more source

Leptin receptor-expressing pericytes mediate access of hypothalamic feeding centers to circulating leptin

Cell Metabolism, 2021
Clement Bourguignon, Kai-Florian Storch   +1 more
exaly