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Role of leptin and leptin receptors in hematological malignancies
Leukemia & Lymphoma, 2015Leptin is an adipose-derived cytokine that has an important role in bodyweight homeostasis and energy balance. There are a number of studies which have suggested that leptin and its receptors dysregulation play a critical role in the development of malignancies including hematological malignancies, mainly via activation of the JAK/STAT pathway which ...
Shahab, Uddin, Ramzi M, Mohammad
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Leptin, Leptin Receptors, and the Control of Body Weight
Nutrition Reviews, 2009The assimilation, storage, and disposition of nutrient energy constitute a complex homeostatic system central to the survival of both prokaryotic and eukaryotic organisms. In vertebrates, and especially among land dwelling mammalian species, the ability to store large quantities of energy-dense fuel in the form of adipose tissue triglyceride permits ...
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Nihon rinsho. Japanese journal of clinical medicine, 2002
Yoshihiro, Ogawa, Kazuwa, Nakao
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Yoshihiro, Ogawa, Kazuwa, Nakao
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Leptin revisited: its mechanism of action and potential for treating diabetes
Nature Reviews Drug Discovery, 2012Roberto Coppari
exaly