Results 251 to 260 of about 49,123 (292)
Functional roles of NR4A transcription factors in GnRH regulation of gonadotropin gene expression and secretion in rat primary pituitary cells. [PDF]
J Reprod DevTerashima R +3 more
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Mutations of LH and FSH receptors
Journal of Endocrinological Investigation, 2000 Gonadotropins control male and female gonadal function by acting through specific receptors. The recent description of several mutations in LH and FSH receptors has significantly improved our understanding of the pathophysiology of several sexual disorder. Both gain- and loss-of-function germline mutations leading to constitutive receptor activation or
P, Beck-Peccoz, R, Romoli, L, Persani
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Seminars in Reproductive Medicine, 2002
In this article the role of LH receptor gene mutations in patients with aberrant sex differentiation is discussed. In a dominant autosomal familial form of precocious puberty in boys (familial male-limited precocious puberty) LH receptor gene mutations have been identified.
Themmen, Axel, Verhoef-Post, M
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In this article the role of LH receptor gene mutations in patients with aberrant sex differentiation is discussed. In a dominant autosomal familial form of precocious puberty in boys (familial male-limited precocious puberty) LH receptor gene mutations have been identified.
Themmen, Axel, Verhoef-Post, M
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Temporal relationship of the prolactin‐dependent LH‐induced LH receptor to the LH stimulus
Journal of Cellular Physiology, 1988AbstractThe time course for LH induction of luteinizing hormone (LH) receptors as reflected in binding of 125l‐labeled hCG was investigated in hypophysecto‐mized adult male rats. A low dose of oLH (10 μg) was administered to hypophysectomized adult male rats following pretreatments with prolactin, follicle‐stimulating hormone (FSH), growth hormone (GH),
M O, Hussein, W B, Zipf
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Localization of lh receptors on luteal cells with a ferritin-lh conjugate
Molecular and Cellular Endocrinology, 1979In order to study the distribution of LH (HCG) receptors on luteal cells ferritin was coupled to ovine LH with glutaraldehyde and purified by gel chromatography. The conjugate (FELH) competed with 125I-hCG for binding to isolated luteal membranes and stimulated a dose-dependent release of progesterone (P) from isolated luteal cells which was inhibited ...
J L, Luborsky, H R, Behrman
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Activating and inactivating mutations in LH receptors
Molecular and Cellular Endocrinology, 1998The glycoprotein hormones luteinizing hormone (LH) and human chorionic gonadotropin (hCG), both of which act through the LH receptor, play an important role in the regulation of both male and female gonadal function. Testicular androgen production by the Leydig cells is almost entirely dependent on LH/hCG action, while in the ovary LH triggers both ...
Themmen, A.P.N. +2 more
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Consequences of targeted inactivation of LH receptors
Molecular and Cellular Endocrinology, 2002The inactivation of luteinizing hormone (LH) receptors was neither lethal nor it had any effect on sex differentiation. However, it dramatically reduced the growth and development of gonads and the reproductive tract. As a result, both female and male animals were infertile. Serum LH levels were dramatically elevated, follicle stimulating hormone (FSH)
C V, Rao, Z M, Lei
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Endocrinology, 1987
In male Syrian hamsters, seasonal transitions between reproductive activity and quiescence are accompanied by major alterations in testicular binding of LH/hCG and PRL. These alterations are believed to be due to the photoperiod-induced changes in PRL secretion, but other adenohypophyseal hormones appear to be involved as well. To elucidate the role of
A, Bartke +4 more
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In male Syrian hamsters, seasonal transitions between reproductive activity and quiescence are accompanied by major alterations in testicular binding of LH/hCG and PRL. These alterations are believed to be due to the photoperiod-induced changes in PRL secretion, but other adenohypophyseal hormones appear to be involved as well. To elucidate the role of
A, Bartke +4 more
openaire +2 more sources