Results 61 to 70 of about 84,180 (270)
State-Dependent and -Independent Effects of Dialyzing Excitatory Neuromodulator Receptor Antagonists into the Ventral Respiratory Column [PDF]
, 2017 Unilateral dialysis of the broad-spectrum muscarinic receptor antagonist atropine (50 mM) into the ventral respiratory column [(VRC) including the pre-Bötzinger complex region] of awake goats increased pulmonary ventilation (V̇i) and breathing frequency (
Burgraff, Nicholas J. +7 more
core +2 more sources
Advanced Science, EarlyView.The action spectrum of a tailored azobenzene is shifted toward bio‐optical window through the chemical modification of its singlet and triplet energy levels. Consequently, the bidirectional photo‐switching of azobenzene in physiological conditions is achieved when excited by red and far‐red light, which offers greater tissue penetration.
Mila Miroshnichenko +11 more
wiley +1 more source
Frontiers in Neural Circuits, 2011 Acetylcholine and the activation of muscarinic receptors influence the activity of neural networks generating locomotor behaviour in the mammalian spinal cord.
Sandrine S Bertrand +1 more
doaj +1 more source
Cholinergic regulation of mood: from basic and clinical studies to emerging therapeutics. [PDF]
, 2019 Mood disorders are highly prevalent and are the leading cause of disability worldwide. The neurobiological mechanisms underlying depression remain poorly understood, although theories regarding dysfunction within various neurotransmitter systems have ...
Dulawa, Stephanie C, Janowsky, David S
core
Cholinergic modulation of dopamine overflow in the rat neostriatum: A fast cyclic voltammetric study in vitro [PDF]
, 1994 Stimulus-evoked dopamine overflow in rat neostriatal slices was determined using fast cyclic voltammetry. The dopamine efflux induced by intrastriatal stimulation increased with stimulus intensity and was found to be enhanced by more than 100% upon ...
Kudernatsch, Martina, Sutor, Bernd
core +1 more source
Making Sweat Measurable: Induction, Sampling, and Refreshment in Wearable Biofluid Sensing
Advanced Science, EarlyView.Wearable sweat sensing relies not only on chemical detection but also on controlled biofluid management. This Review integrates sweat physiology, induction strategies, and microfluidic sampling architectures, demonstrating how flux, transport, and refreshment shape measurement reliability.
Soyoung Shin, Wei Gao
wiley +1 more source
Journal of Pharmacological Sciences, 2008 Muscarinic receptors in the human and rat lower urinary tract (urinary bladder detrusor muscle and mucosa, and prostate) were identified by intact tissue segment binding assays with two radioligands, and the effects of prolonged receptor activation in ...
Abu Syed Md Anisuzzaman +8 more
doaj +1 more source
Delineating muscarinic receptor functions [PDF]
Proceedings of the National Academy of Sciences, 1999 Acetylcholine, as the first chemical molecule to be established as a neurotransmitter, has attracted enduring interest from researchers over several decades. However, deciphering all of the physiological manifestations associated with actions of this molecule has been difficult, and many mysteries of cholinergic neurotransmission still remain to be ...
R R, Gainetdinov, M G, Caron
openaire +2 more sources
An update on the efficacy and safety of aclidinium bromide in patients with COPD
Therapeutic Advances in Respiratory Disease, 2011 Aclidinium is a potent and selective muscarinic antagonist, which interacts rapidly with muscarinic receptors and shows subnanomolar affinity for the five human muscarinic receptors (M 1 –M 5 ); its association rate for the M 3 receptor is similar to ...
Khuder Alagha +3 more
doaj +1 more source
The role of muscarinic receptors in the beneficial effects of adenosine against myocardial reperfusion injury in rats. [PDF]
PLoS ONE, 2011 Adenosine, a catabolite of ATP, displays a wide variety of effects in the heart including regulation of cardiac response to myocardial ischemia and reperfusion injury.
Lei Sun +8 more
doaj +1 more source