Results 61 to 70 of about 592,770 (271)
Modulation of cholinergic synaptic transmission in an identified locust sensory pathway [PDF]
, 2000 The monosynaptic connection between the locust forewing stretch receptor (fSR) and the first basalar motoneuron (BAl) is part of a sensory pathway involved in flight.
Judge, Sarah Jane
core
Constitutive activity of muscarinic acetylcholine receptors.
, 2006 We review the literature describing constitutive activity of the five muscarinic acetylcholine receptors in native and recombinant systems and discuss the effect of constitutive activity on muscarinic pharmacology in the context of modern models of ...
Spalding, Tracy, Burstein, Ethan
core +1 more source
Role of M4 muscarinic receptors in the central nervous system [PDF]
, 2020 Muscarinic receptors type 4 are one of the five subtypes of muscarinic receptors, that are members of cholinergic receptors family, together with nicotinic receptors.
Křížová, Monika
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Chemistry – A European Journal, EarlyView.Starting from carboxylic acids and Selectfluor‐derivatives, functionalized diazabicyclooctanes can be obtained via a novel Polonovski‐type rearrangement proceeding under mild reaction conditions. Besides their use in organic synthesis the unique structure and reactivity of the rearrangement products enables applications in medicinal chemistry ...
Jakob Kuhn +5 more
wiley +1 more source
The muscarinic antagonists scopolamine and atropine are competitive antagonists at 5-HT3 receptors [PDF]
, 2016 Scopolamine is a high affinity muscarinic antagonist that is used for the prevention of post-operative nausea and vomiting. 5-HT3 receptor antagonists are used for the same purpose and are structurally related to scopolamine.
Thompson, Andrew J. +2 more
core +5 more sources
Phenotyping patients with chronic obstructive pulmonary disease and heart failure
ESC Heart Failure, Volume 12, Issue 2, Page 900-911, April 2025.Central illustration. Abbreviations: ACEi, angiotensin‐converting enzyme inhibitor; ARB, angiotensin receptor blocker; ARNi, angiotensin‐receptor‐neprilysin inhibitor; CI, confidence interval; COPD, chronic obstructive pulmonary disease; CRT, cardiac resynchronization therapy; CV, cardiovascular; EF, ejection fraction; eGFR, estimated glomerular ...
Peter Moritz Becher +12 more
wiley +1 more source
Cooperative Glutamatergic and Cholinergic Mechanisms Generate Short-Term Modifications of Synaptic Effectiveness in Prepositus Hypoglossi Neurons [PDF]
, 2005 To maintain horizontal eye position on a visual target after a saccade, extraocular motoneurons need a persistent (tonic) neural activity, called "eye-position signal," generated by prepositus hypoglossi (PH) neurons.
Navarro Lopez, JDD +2 more
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Muscarinic receptors and drugs in cardiovascular medicine
, 1995 The parasympathetic system and its associated muscarinic receptors have been the subject of a renaissance of interest for the following two main reasons: (1) the association of endothelial muscarinic receptors and the nitric oxide (NO) pathway; (2) the ...
van Zwieten, P. A., Doods, H. N.
core +1 more source
Epileptic Disorders, EarlyView.Abstract Objective Traumatic brain injury (TBI) is a leading cause of acquired epilepsy, death, and long‐term disability, yet reliable biomarkers to predict chronic sequelae such as post‐traumatic epilepsy (PTE) remain limited. We evaluated the associations between circulating blood biomarkers of neuronal, glial, and synaptic injury and the subsequent ...
Michele Longoni Calió +11 more
wiley +1 more source
Journal of Pharmacological Sciences, 2016 Muscarinic and purinergic (P2X) receptors play critical roles in bladder urothelium under physiological and pathological conditions. Aim of present study was to characterize these receptors in rat bladder urothelium and detrusor muscle using selective ...
Masaki Ogoda +4 more
doaj +1 more source