Results 261 to 270 of about 2,394,761 (293)

Nicotinic receptors and Parkinson's disease

European Journal of Pharmacology, 2000
Accumulating evidence indicates that nicotinic receptors play a role in basal ganglia function. Furthermore, nicotine administration may be neuroprotective in animal models of nigrostriatal degeneration, while cigarette smoking is inversely correlated with Parkinson's disease.
Maryka Quik, Gayathri Jeyarasasingam
openaire   +3 more sources

The Nicotinic Acetylcholine Receptor

1985
The acetylcholine receptor (AcChR) from Torpedo electroplax has been isolated both in its native membrane-bound state and by affinity chromatography after solubilization (see Conti-Tronconi and Raftery, 1982). Purified membrane fragments can reseal, forming closed, right-side-out vesicles, which can be used for both functional and structural studies ...
Michael A. Raftery, Susan M. J. Dunn, Rebecca D. Crawford, Bianca M. Conti-Tronconi, David S. Middlemas   +4 more
openaire   +2 more sources

Nicotine receptor mapping

European Journal of Nuclear Medicine, 1996
Frank Grünwald, H. J. Biersack, Wolfgang Kuschinsky   +2 more
openaire   +3 more sources

Crystal structure of an ACh-binding protein reveals the ligand-binding domain of nicotinic receptors

Nature, 2001
Katjua Brejc, W. Dijk, R. Klaassen, M. Schuurmans, J. Oost, A. Smit, T. Sixma   +6 more
semanticscholar   +1 more source

Multiple Nicotinic Receptors: Nicotinic Ligands with Different Specificities

, 1987
J. Sloan, W. Martin, Walter T. Smith
semanticscholar   +1 more source

Nicotine Receptors and Infections

2006
Tobacco smoking is a significant risk factor in respiratory diseases including chronic obstructive lung disease and pneumonia.The bronchial alveolar lavage fluids obtained from tobacco smokers have increased number of alveolar macrophages and neutrophils.(1,2) Moreover, compared with nonsmokers, alveolar macrophages from smokers appear to be in an ...
openaire   +2 more sources

Nicotinic acetylcholine receptors and nicotinic cholinergic mechanisms of the central nervous system.

Annual Review of Pharmacology and Toxicology, 2007
J. Dani, D. Bertrand
semanticscholar   +1 more source

Presynaptic nicotinic ACh receptors

Trends in Neurosciences, 1997
S. Wonnacott
semanticscholar   +1 more source

Nicotinic acetylcholine receptors: from basic science to therapeutics.

Pharmacology and Therapeutics, 2013
R. Hurst, H. Rollema, D. Bertrand
semanticscholar   +1 more source

Neuronal Nicotinic Acetylcholine Receptors

1996
Studies of the structure and function of neuronal nicotinic acetylcholine receptors (AChRs) evolved out of studies of muscle AChRs. This review will begin with a brief summary of muscle type AChRs because they are the archetype for studies of neuronal nicotinic AChRs in particular and ligand-gated ion channels in general.
openaire   +3 more sources