Results 171 to 180 of about 25,455 (216)

New and emerging pharmacologic treatments for MDD. [PDF]

Front Psychiatry
Uyar A, Gonul AS.
europepmc   +1 more source

Cancer Pain Is Not One-Size-Fits-All: Evolving from Tradition to Precision. [PDF]

Clin Pract
Shapoo N, Rehman A, Izaguirre-Rojas C, Gotlieb V, Boma N.   +4 more
europepmc   +1 more source

Renal Implications of Kappa Opioid Receptor Signaling in Sprague-Dawley Rats. [PDF]

Function (Oxf)
Didik S, Golosova D, Zietara A, Bohovyk R, Ahrari A, Levchenko V, Kravtsova O, Taneja K, Khedr S, Semenikhina M, Palygin O, Staruschenko A.   +11 more
europepmc   +1 more source

A New Trick of Old Dogs: Can Kappa Opioid Receptor Antagonist Properties of Antidepressants Assist in Treating Treatment-Resistant Depression (TRD)? [PDF]

Pharmaceuticals (Basel)
Schreiber S, Keidan L, Pick CG.
europepmc   +1 more source

Sex-specific genetics underlie increased chronic pain risk in women: decoding the genetic architecture of chronic pain. Comment on Br J Anaesth 2025; 135: 401-5. [PDF]

Br J Anaesth
Zeng J, Zhou Z.
europepmc   +1 more source

Seeing the bigger picture: endogenous opioids mediate attentional broadening after reward receipt. [PDF]

Psychol Med
van Steenbergen H, Gable P, Fagan H, Molteni L, Midveris A, Huneke N.   +5 more
europepmc   +1 more source

Targeting the kappa opioid receptor for analgesia and antitumour effects. [PDF]

Br J Anaesth
Lambert DG, Mincer JS.
europepmc   +1 more source

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Antagonists of the kappa opioid receptor

Bioorganic & Medicinal Chemistry Letters, 2014
The research community has increasingly focused on the development of OPRK antagonists as pharmacotherapies for the treatment of depression, anxiety, addictive disorders and other psychiatric conditions produced or exacerbated by stress. Short-acting OPRK antagonists have been recently developed as a potential improvement over long-acting prototypic ...
Mariangela, Urbano, Miguel, Guerrero, Hugh, Rosen, Edward, Roberts   +3 more
openaire   +2 more sources