Results 1 to 10 of about 29,047 (251)
Molecules, 2010 The synthesis of a small library of dihydrouracils spiro-fused to pyrrolidines is described. These compounds are synthesized from b-aryl pyrrolidines, providing products with the 2-arylethyl amine moiety, a structural feature often encountered in ...
Daniel Blanco-Ania +5 more
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One-Pot Route from Halogenated Amides to Piperidines and Pyrrolidines
Molecules, 2022 Piperidine and pyrrolidine derivatives are important nitrogen heterocyclic structures with a wide range of biological activities. However, reported methods for their construction often face problems of requiring the use of expensive metal catalysts ...
Qiao Song +5 more
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Molecules, 2022 The AgOAc-catalysed reaction of 3-nitro-2-phenyl-2H-chromenes with stabilized azomethine ylides generated from the imines based on methyl glycinate and arylaldehydes leads to a mixture of endo and endo’ isomers of the corresponding chromeno[3,4-c ...
Ivan A. Kochnev +6 more
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Communications Chemistry, 2023 Polycyclic N-heterocycles are important structural motifs commonly found in bioactive compounds, however, their selective construction via the cyclization of allenynes remains challenging yet highly desirable.
Kua-Fei Wei +6 more
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Molecules, 2021 1,3-Dipolar cycloaddition reactions of 2-substituted 5-R-3-nitropyridines and isomeric 3-R-5-nitropyridines with N-methyl azomethine ylide were studied. The effect of the substituent at positions 2 and 5 of the pyridine ring on the possibility of the [3 ...
Maxim A. Bastrakov +3 more
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Beilstein Journal of Organic Chemistry, 2021 A new highly diastereoselective synthesis of the polyhydroxylated pyrrolidine alkaloid (±)-codonopsinol B and its N-nor-methyl analogue, starting from achiral materials, is presented.
Lukáš Ďurina +7 more
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Synthesis and Biological Study of Some New Pyrrolidines [PDF]
مجلة التربية والعلم, 2007 A series of Schiff bases N-Arylidene benzylamie (1-6) have been prepared, and through 1,3-anionic cycloaddition under strong basic conditions were added to benzoquinone to afford the fused new pyrrolidines (7-12).
A.J. Al-Hamdany +2 more
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1,3-Dipolar Cycloadditions of N-Benzyl Furfuryl Nitrones with Electron-rich Alkenes
Molecules, 2000 The 1,3-dipolar cycloaddition reaction of N-benzyl-C-(2-furyl)nitrones with electron-rich alkenes gives preferentially trans-substituted 3,5-disubstituted isoxazolidines (endo approach).
Tomas Tejero +3 more
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Synthesis of 1-phenyl-3-pyrroline in water
Orbital: The Electronic Journal of Chemistry, 2012 Pyrrolines are bioactive compounds and can be used as starting materials or as intermediates in the synthesis of natural products [1,2]. N-phenyl-pyrrolines have been prepared by reaction of N-propargylanilines catalyzed by Cu(I) [3] or the ring-closing ...
Thiago Muniz de Souza +2 more
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Copper(I)-catalyzed asymmetric 1,3-dipolar cycloaddition of 1,3-enynes and azomethine ylides
Nature Communications, 2023 Herein, we report a copper(I)-catalyzed asymmetric 1,3-dipolar cycloaddition of azomethine ylides and 1,3-enynes, which provides a series of chiral poly-substituted pyrrolidines in high regio-, diastereo-, and enantioselectivities. Both 4-aryl-1,3-enynes
Bo-Ran Wang +6 more
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