Results 11 to 20 of about 29,047 (251)

Photochemical Catalyst-Free Synthesis of Pyrrolidines via a Hofmann–Loffler–Freytag Reaction [PDF]

Molecules
The Hoffman–Loffler–Freytag (HLF) reaction is one of the first transformations to achieve remote C(sp3)-H functionalization and simultaneously provide useful building blocks from readily available reagents. Herein, we propose a photochemical protocol for
Athina S. J. Shkembi, Luca Pasqualon, Stamatis K. Serviou, Manos V. G. Lantzanakis, Christoforos G. Kokotos   +4 more
doaj   +2 more sources

Recent Advances in Intramolecular C─N Bond Formation for Pyrrolidine Synthesis [PDF]

ChemistryOpen
Pyrrolidines constitute a privileged class of nitrogen heterocycles that are ubiquitous in pharmaceuticals, bioactive molecules, and functional materials, thereby continuing to stimulate the development of efficient and versatile synthetic strategies ...
Rasma Kroņkalne, Māris Turks
doaj   +2 more sources

Dialkylaminoalkylation of β-ketosulfones via ring-opening of 3-sulfonylpyrrolidines [PDF]

Beilstein Journal of Organic Chemistry
Herein, a three-step method for the simultaneous dialkylaminoethylation and heteromethylation of active methylene β-ketosulfones, promoted by a leaving benzoyl group, is proposed.
Evgeny M. Buev, Alexander V. Pavlushin, Vladimir S. Moshkin, Vyacheslav Y. Sosnovskikh   +3 more
doaj   +2 more sources

Synthesis of a New Chiral Pyrrolidine [PDF]

Molecules, 2010
The synthesis of a new chiral pyrrolidine has been performed using 2,3-O-isopropylidene-D-erythronolactol as a suitable starting material.
Pilar García, Enrique F. Iglesias, Isidro S. Marcos, Narciso M. Garrido, Rosalina F. Moro, Marta G. Núñez, Mari Fe. Flores, David Díez   +7 more
doaj   +3 more sources

Skeletal editing of tetrahydrofurans to pyrrolidines through O-to-N single atom swap [PDF]

Nature Communications
Skeletal editing has emerged as a powerful strategy for organic synthesis, addressing a long-standing synthetic challenge between molecular scaffolds.
Shihan Geng, Tieqiao Wang, Qingxuan Kong, Dunhang Ouyang, Changwei Jiang, Ning Jiao, Song Song   +6 more
doaj   +2 more sources

ELECTROCHEMICAL REDUCTION OF 2,2,5,5-TETRAMETHYLPYRROLINE DERIVATIVES TO CORRESPONDING PYRROLIDINES

Advanced Engineering Research, 2012
The reduction technique of 2,2,5,5-tetramethylpyrroline compounds to pyrrolidines on sodium amalgam preformed under the electrolysis of sodium hydroxide solution is described.
Irina Y. Zhukova, Igor S. Kashparov, Darya S. Garbuznyak   +2 more
doaj   +1 more source

ELECTROCHEMICAL REDUCTION OF 2,2,5,5-TETRAMETHYLPYRROLINE DERIVATIVES TO CORRESPONDING PYRROLIDINES

Вестник Донского государственного технического университета, 2018
The reduction technique of 2,2,5,5-tetramethylpyrroline compounds to pyrrolidines on sodium amalgam preformed under the electrolysis of sodium hydroxide solution is described.
Irina Y. Zhukova, Igor S. Kashparov, Darya S. Garbuznyak   +2 more
doaj   +1 more source

Synthesis and Suzuki-Miyaura Cross-Coupling of α-Borylated Pyrrolidines [PDF]

, 2021
This thesis describes the steps taken towards the development of a methodology for the synthesis and Suzuki-Miyaura cross-coupling of α-borylated pyrrolidines. Two main methods were explored for the synthesis of α-borylated pyrrolidines.
Howman, Chloe Elizabeth
core   +2 more sources

Direct synthesis of functionalized 3-pyrrolidines and 4-piperidines using the borrowing hydrogen methodology [PDF]

, 2023
The Ir(III)-catalyzed synthesis of 3-pyrrolidinols and 4-piperidinols combining 1,2,4-butanetriol or 1,3,5-pentanetriol with primary amines was carried out.
Florence, Popowycz, Maiwenn, Jacolot, Jordan, François, Malvina, Larduinat, Jacolot, Maiwenn, Popowycz, Florence, François, Jordan, Larduinat, Malvina, Florence Popowycz, Malvina Larduinat, Jordan François, Maiwenn Jacolot   +11 more
core   +1 more source

Brønsted base-catalyzed assembly of sulfochromeno [4,3-b] pyrrolidines via tandem [3+2] cycloaddition-SuFEx click reaction of ethenesulfonyl fluorides and azomethine ylides [PDF]

, 2022
The synthesis of sulfochromeno [4,3-b] pyrrolidines is described. Under the catalysis of 20 mol% Brønsted base and using 4Å molecular sieves as HF scavenger, imines derived from salicylaldehydes and diethyl aminomalonate react with ethenesulfonyl ...
Qichao, Zhang, Jichang, Liu, Fang, Zhang, Lin, He, Bin, Dai   +4 more
core   +2 more sources