Results 21 to 30 of about 29,810 (265)

Highly diastereoselective 1,3-dipolar cycloaddition of nonstabilized azomethine ylides to 3-nitro-2-trihalomethyl-2H-chromenes: Synthesis of 1-benzopyrano[3,4-c]pyrrolidines [PDF]

, 2013
Reactions of 3-nitro-2-trifluoro(trichloro)methyl-2H-chromenes, including 2-unsubstituted derivatives, with N-alkyl-α-amino acids (sarcosine, proline) and paraformaldehyde proceed diastereoselectively to give 1-benzopyrano[3,4-c]pyrrolidines in good ...
Barkov, A. Y., Kodess, M. I., Korotaev, V. Y., Matochkina, E. G., Moshkin, V. S., Sosnovskikh, V. Y.   +5 more
core   +1 more source

Bis(oxotremorine) fumarate bis(fumaric acid)

IUCrData, 2022
The title compound, bis(oxotremorine) fumarate bis(fumaric acid) {systematic name: 1-[4-(2-oxopyrrolidin-1-yl)but-2-ynyl]pyrrolidinium (2E)-but-2-enedioate bis[(2E)-but-2-enedioic acid]}, 2C12H19N2O+·C4H2O42−·2C4H4O4, has a single oxotremorine monocation
Marilyn Naeem, Andrew R. Chadeayne, James A. Golen, David R. Manke   +3 more
doaj   +1 more source

Asymmetric 1,3-Dipolar Cycloadditons of Stabilized Azomethine Ylides with Nitroalkenes [PDF]

, 2014
This review highlights the biological importance of many polysubstituted nitro-prolines and -pyrrolidines. Their preparation using asymmetric 1,3-dipolar cycloadditions of azomethine ylides with nitroalkenes using diastereoselective and enantioselective ...
Nájera, Carmen, Sansano, Jose M.
core   +2 more sources

Cellulose recycling as a source of raw chirality [PDF]

, 2013
Modern organic chemistry requires easily obtainable chiral building blocks that show high chemical versatility for their application in the synthesis of enantiopure compounds.
Biava, Hernan Daniel, Botta, María Celeste, Corne, Valeria, Giordano, Enrique David Victor, Giri, German Francisco, Llompart, David Fernando, Mangione, Maria Ines, Mata, Ernesto Gabino, Sarotti, Ariel Marcelo, Spanevello, Rolando Angel, Suarez, Alejandra Graciela   +10 more
core   +2 more sources

Copper- and Silver-Catalyzed Reactions of Active Methylene Isocyanides: Facile Access to Highly Substituted Five- and Six-Membered Heterocycles. [PDF]

Chemistry
This review summarizes recent advances in copper‐ and silver‐catalyzed reactions of active methylene isocyanides for the synthesis of highly substituted five‐ and six‐membered heterocycles. Emphasis is placed on [3+n] cycloadditions, annulations, and asymmetric strategies, highlighting current limitations and future opportunities in heterocycle ...
George J, Oh K.
europepmc   +2 more sources

X=Y–ZH compounds as potential 1,3-dipoles. Part 64: Synthesis of highly substituted conformationally restricted and spiro nitropyrrolidines via Ag(I) catalysed azomethine ylide cycloadditions [PDF]

, 2008
1,3-Dipolar reactions of imines of both acyclic and cyclic α-amino esters with a range of nitroolefins using a combination of AgOAc or Ag2O with NEt3 are described.
Albert, Amornraksa, Ayerbe, Becker, Berger, Bourguignon, Bryce, Cecilia Orgaz de la Cierva, Colin Kilner, Crooks, Dondas, Díaz-Ortiz, Fejes, Fejes, Gentles, Grigg, Grigg, Grigg, Grigg, Grigg, Grigg, Grigg, Grigg, Grigg, H. Ali Dondas, Hill, Kabalka, Krapcho, Lee, Mohammed A.B. Sarker, Nielson, Norman, Nyerges, Nyerges, Nyerges, Nyerges, Nyerges, Pak, Peterli, Pinna, Poornachandran, Poornachandran, Poornachandran, Ram, Rang, Ronald Grigg, Sader-Bakaouni, Shorter, Song, Thurkauf, Vivanco, Yan   +51 more
core   +1 more source

Synthesis of 3-Substituted Pyrrolidines via Palladium-Catalyzed Hydroarylation

iScience, 2018
Summary: Metal-catalyzed reactions have revolutionized synthetic chemistry, allowing access to unprecedented molecular architectures with powerful properties and activities. Nonetheless, some transformations remain sparse in number, or out of reach, even
Joseph B. Sweeney, Julien Doulcet, Bimod Thapa   +2 more
doaj   +1 more source

Synthesis of Chromen[4,3-b]pyrrolidines by Intramolecular 1,3-Dipolar Cycloadditions of Azomethine Ylides: An Experimental and Computational Assessment of the Origin of Stereocontrol [PDF]

, 2015
Azomethine ylides, generated from imine-derived O-cinnamyl or O-crotonyl salicylaldeyde and α-amino acids, undergo intramolecular 1,3-dipolar cycloaddition, leading to chromene[4,3-b]pyrrolidines.
Arrieta, Ana, Barcellos, Julio C.F., Cossío Mora, Fernando Pedro, Cossío, Unai, Costa, Paulo R.R., Cózar Ruano, Abel de, Dias, Ayres G., Nájera, Carmen, Sansano, Jose M.   +8 more
core   +2 more sources

N-(Pyrrolidin-1-ylcarbothioyl)benzamide [PDF]

Acta Crystallographica Section E Structure Reports Online, 2011
In the title compound, C(12)H(14)N(2)OS, the pyrrolidine ring adopts an envelope conformation with the C atom at the 3-position as the flap and makes a dihedral angle of 65.80 (9)° with the benzene ring. In the crystal, N-H⋯O hydrogen bonds join c-glide related mol-ecules into chains extended along [001] that are further connected into (100) layers via
Al-Abbasi, Aisha A., Mohamed Tahir, Mohamed Ibrahim, Kassim, Mohammad   +2 more
openaire   +3 more sources

Ring Expansion of Vinylaziridines through the Strain-Release Pericyclic Reaction: Recent Developments and Applications

Molecules, 2013
Recent syntheses of azetidines, pyrrolidines, piperidines and azepines through cycloaddition or sigmatropic rearrangements of vinylaziridines are described. Applications to natural product synthesis and mechanistic investigations are also summarized.
Yu Mi Heo, Seung-Mann Paek
doaj   +1 more source