Results 31 to 40 of about 27,991 (255)
Synthesis of 3-Substituted Pyrrolidines via Palladium-Catalysed Hydroarylation [PDF]
, 2018 Metal-catalysed reactions have revolutionised synthetic chemistry, allowing access to unprecedented molecular architectures with powerful properties and activities. Nonetheless, some transformations remain sparse in number, or out of reach, even with the
Joe, Sweeney +2 more
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1,3-Dipolar Cycloadditions of N-Benzyl Furfuryl Nitrones with Electron-rich Alkenes
Molecules, 2000 The 1,3-dipolar cycloaddition reaction of N-benzyl-C-(2-furyl)nitrones with electron-rich alkenes gives preferentially trans-substituted 3,5-disubstituted isoxazolidines (endo approach).
Tomas Tejero +3 more
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Synthesis of 1-phenyl-3-pyrroline in water
Orbital: The Electronic Journal of Chemistry, 2012 Pyrrolines are bioactive compounds and can be used as starting materials or as intermediates in the synthesis of natural products [1,2]. N-phenyl-pyrrolines have been prepared by reaction of N-propargylanilines catalyzed by Cu(I) [3] or the ring-closing ...
Thiago Muniz de Souza +2 more
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Acta Crystallographica Section E Structure Reports Online, 2012 In the title compound, C(4)H(5)NO(2), the non-H atoms are nearly coplanar, with a maximum deviation of 0.030 (1) Å. In the crystal, pairs of mol-ecules are linked by N-H⋯O hydrogen bonds into inversion dimers.
Min Yu, Xing Huang, Feng Gao
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Copper(I)-catalyzed asymmetric 1,3-dipolar cycloaddition of 1,3-enynes and azomethine ylides
Nature Communications, 2023 Herein, we report a copper(I)-catalyzed asymmetric 1,3-dipolar cycloaddition of azomethine ylides and 1,3-enynes, which provides a series of chiral poly-substituted pyrrolidines in high regio-, diastereo-, and enantioselectivities. Both 4-aryl-1,3-enynes
Bo-Ran Wang +6 more
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Molecules, 2013 Recent syntheses of azetidines, pyrrolidines, piperidines and azepines through cycloaddition or sigmatropic rearrangements of vinylaziridines are described. Applications to natural product synthesis and mechanistic investigations are also summarized.
Yu Mi Heo, Seung-Mann Paek
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Bis(oxotremorine) fumarate bis(fumaric acid)
IUCrData, 2022 The title compound, bis(oxotremorine) fumarate bis(fumaric acid) {systematic name: 1-[4-(2-oxopyrrolidin-1-yl)but-2-ynyl]pyrrolidinium (2E)-but-2-enedioate bis[(2E)-but-2-enedioic acid]}, 2C12H19N2O+·C4H2O42−·2C4H4O4, has a single oxotremorine monocation
Marilyn Naeem +3 more
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Selective Electrochemical Oxidation of Functionalized Pyrrolidines
, 2021 A method for the selective electrochemical aminoxyl-mediated Shono-type oxidation of pyrrolidines to pyrrolidinones is described. These transformations show the high selectivity and functional group compatibility. This chemistry also demonstrates the use
Shaoguang Zhang (1652278) +13 more
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Reactions affording novel pyrrolidines catalysed by palladium [PDF]
Pyrrolidines are privileged motifs in drug discovery, ranked among the top five most common non-aromatic N-heterocycles and featured in 37 FDA-approved drugs.
Robinson, Joshua, Doulcet, Julien
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MoleculesN-aryl-substituted pyrrolidines are important moieties widely found in bioactive substances and drugs. Herein, we present a practical reductive amination of diketones with anilines for the synthesis of N-aryl-substituted pyrrolidines in good to excellent
Jianhua Liao +4 more
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