Results 51 to 60 of about 29,810 (265)

Transient and intermediate carbocations in ruthenium tetroxide oxidation of saturated rings

Beilstein Journal of Organic Chemistry, 2019
The ruthenium tetroxide-mediated oxidation of cyclopentane, tetrahydrofuran, tetrahydrothiophene and N-substituted pyrrolidines has been studied computationally by DFT and topological (analysis of the electron localization function, ELF) methods.
Manuel Pedrón, Laura Legnani, Maria-Assunta Chiacchio, Pierluigi Caramella, Tomás Tejero, Pedro Merino   +5 more
doaj   +1 more source

Probing the Influence of Linker Length and Flexibility in the Design and Synthesis of New Trehalase Inhibitors

Molecules, 2018
This work aims to synthesize new trehalase inhibitors selective towards the insect trehalase versus the porcine trehalase, in view of their application as potentially non-toxic insecticides and fungicides.
Giampiero D’Adamio, Matilde Forcella, Paola Fusi, Paolo Parenti, Camilla Matassini, Xhenti Ferhati, Costanza Vanni, Francesca Cardona   +7 more
doaj   +1 more source

Synthesis of Nitrogenated Heterocycles by Asymmetric Transfer Hydrogenation of N-(tert-Butylsulfinyl)haloimines [PDF]

, 2013
Highly optically enriched, protected, nitrogenated heterocycles with different ring sizes have been synthesized by a very efficient methodology consisting of the asymmetric transfer hydrogenation of N-(tert-butylsulfinyl)haloimines followed by treatment ...
Ahn K., Almansa R., Almansa R., Alonso D. A., Andersson P. G., Bañón-Caballero A., Bosque I., Brak K., Breuer M., Callebaut G., Collados J. F., Corey E. J., Cutter A. C., Daly J. W., Darwish M., David Guijarro, Dema H. K., Denolf B., Denolf B., Dua R., Elliott R. L., Ellman J. A., Ellman J. A., Fattorusso E., Ferreira F., Gowda M., Guijarro D., Guijarro D., Guijarro D., Guijarro D., Guijarro D., Guijarro D., Guo T., Hansen K. B., Hart H., Hodgson D. M., Hodgson D. M., Holzer M., Kobayashi S., Kosciolowicz A., Lawrence A. K., Leemans E., Leemans E., Lin G.-Q., Lin N.-H., Louvel J., Louvel J., Mao J., Melchiorre P., Michael J. P., Miguel Yus, Noyori R., Nugent T. C., Nájera C., O’Hagan D., Pablo O., Palmer M. J., Patil M. P., Pinho P., Rao M. L. N., Reddy L. R., Reddy L. R., Reddy L. R., Robak M. T., Roth P., Royer J., Samano V., Senanayake C. H., Senter T. J., Siva S. R. N., Sun X., Tanner D., Vaultier M., Voituriez A., Wang C., Yu J., Óscar Pablo   +76 more
core   +2 more sources

CORE: Cholesterol Altered Lipid Nanoparticles for Splenic Expression of mRNA Payloads

Advanced Healthcare Materials, EarlyView.
In this paper researchers introduce CORE LNPs, a new class of lipid nanoparticles engineered to redirect mRNA expression away from the liver and into the spleen, a key immune organ. By combining chemical design with computational tools, they created cholesterol analogs that enable precise spleen‐targeted expression, providing greater applications for ...
Eshan A. Narasipura, Vincent Fung, Rachel VanKeulen‐Miller, Palas B. Tiwade, Owen S. Fenton   +4 more
wiley   +1 more source

Palladium and Platinum 2,4-cis-amino Azetidine and Related Complexes [PDF]

, 2018
Seven N,N’-palladium(II) chloride complexes, one N,N’-palladium(II) acetate complex of 2,4-cis-azetidines where prepared and analyzed by single crystal XRD.
Binder, Choi, Clavier, Coles, Falivene, Feula, Feula, Feula, Fossey, Fossey, Fossey, Fossey, Fossey, Fossey, Gaertner, Graham, Hama Salih, Hambley, Jamieson, Keller, Lee, Lee, Lee, Leonard, Martínez-Olid, Payne, Pelz, Pelz, Poater, Rixe, Saito, Voureka, Yoshizawa, Yoshizawa, Yoshizawa, Álvarez-Casao   +35 more
core   +5 more sources

Azaporphyrinoid‐Based Photo‐ and Electroactive Architectures for Advanced Functional Materials

Advanced Materials, EarlyView.
A long‐standing collaboration between the Torres and Guldi groups has yielded diverse azaporphyrinoid‐based donor‐acceptor nanohybrids with promising applications in solar energy conversion. This conspectus highlights key molecular platforms and structure‐function relationships that govern light and charge management, supporting the rational design of ...
Jorge Labella, Kobra Azizi, Dirk M. Guldi, Tomás Torres   +3 more
wiley   +1 more source

Synthesis of new pyrrolidine-based organocatalysts and study of their use in the asymmetric Michael addition of aldehydes to nitroolefins

Beilstein Journal of Organic Chemistry, 2017
New pyrrolidine-based organocatalysts with a bulky substituent at C2 were synthesized from chiral imines derived from (R)-glyceraldehyde acetonide by diastereoselective allylation followed by a sequential hydrozirconation/iodination reaction.
Alejandro Castán, Ramón Badorrey, José A. Gálvez, María D. Díaz-de-Villegas   +3 more
doaj   +1 more source

A New Class of Substrates for Nucleophilic 5-endo-trig Cyclization, 2-Trifluoromethyl-1-alkenes: Synthesis of Five-Membered Hetero- and Carbocycles That Bear Fluorinated One-Carbon Units [PDF]

, 2008
Disfavored 5-endo-trig cyclizations were achieved in 2-trifluoromethyl-1-alkenes with a nucleophilic nitrogen, oxygen, sulfur, or carbon atom through 1) intramolecular SN2 reaction with loss of a fluoride ion or 2) intramolecular nucleophilic addition to
Ichikawa Junji, Ikeda Masahiro, Iwai Yu, Mori Takashi, Nadano Ryo, 市川 淳士   +5 more
core   +1 more source

Dual‐Physical‐Field Nanocatalysis: Injectable Hydrogel Enables Piezo‐Photothermal Synergy for Breast Cancer Therapy

Advanced Science, EarlyView.
ABSTRACT Piezocatalytic therapy (PCT) harnesses mechanical energy to generate tumor‐lethal reactive oxygen species (ROS), but its efficacy is limited by rapid electron‐hole recombination and poor intratumoral retention. To overcome these limitations, we engineered heterostructured BiOCl@CuO nanosheets embedded in an injectable, conductive ...
Can Tian, Shihan Xiao, Xuan Chen, Danni Zhang, Zizhen Liu, Jing Wang, Ning Xie, Wei Li   +7 more
wiley   +1 more source

Synthesis and biological evaluation of nojirimycin- and pyrrolidine-based trehalase inhibitors

Beilstein Journal of Organic Chemistry, 2012
A small set of nojirimycin- and pyrrolidine-based iminosugar derivatives has been synthesized and evaluated as potential inhibitors of porcine and insect trehalases.
Davide Bini, Francesca Cardona, Matilde Forcella, Camilla Parmeggiani, Paolo Parenti, Francesco Nicotra, Laura Cipolla   +6 more
doaj   +1 more source