Results 71 to 80 of about 23,799 (225)
Silyl-substituted pyrrolidines have gained increased interest for the design of new catalyst scaffolds. The molecular structures of four enantiomerically-pure 2-silylpyrrolidinium salts are reported.
Jonathan O. Bauer, Carsten Strohmann
doaj +1 more source
Retro‐Hetero‐Michael Addition Strategies in Organic Synthesis
In this review, synthetic approaches to carbo‐ and heterocyclic compounds, including natural products, published in the last 15 years (2011–2025) which have either relied upon or included a retro‐hetero‐Michael addition step at any stage are discussed.
Dina Scarpi, Ernesto G. Occhiato
wiley +1 more source
Infrared Irradiation‐Assisted Pd/Cu Catalysis for Sustainable C–N Cross‐Coupling Reactions
A combined Pd/Cu catalytic system is demonstrated to be highly effective in promoting infrared irradiation‐assisted Buchwald–Hartwig aminations under nonanhydrous and open‐air conditions, using only a stoichiometric amount of a green reaction solvent.
Ambra M. Fiore +4 more
wiley +1 more source
Abstract Since the early 1960s, nanotechnology has been a critical area of science, allowing for the development of sophisticated nanomaterials. Nanofibers, one of the most widely used nanotechnological drug delivery systems, have emerged as a highly versatile platform within modern pharmaceutical sciences.
Heybet Kerem Polat +7 more
wiley +1 more source
Plasmepsins as Antimalarial Drug Targets—Then, Now, and the Future
ABSTRACT Malaria is a devastating disease caused by Plasmodium parasites. Plasmodium parasites express ten cathepsin D‐like aspartyl proteases, called plasmepsins (PMs). These PMs have diverse roles fulfill diverse functions throughout the parasite's lifecycle, though several exhibit functional redundancies. Among them, PMV, PMIV, and PMX are essential
Brad E. Sleebs
wiley +1 more source
The continuing significance of chiral agrochemicals
In the time frame 2018–2023, around 43% of the 35 chiral agrochemicals introduced to the market (herbicides, fungicides, insecticides, acaricides, and nematicides) contain one or more stereogenic centers in the molecule, and almost 69% of them have been marketed as racemic mixtures of enantiomers or stereoisomers.
Peter Jeschke
wiley +1 more source
A series of novel pyrene‐linked heterocyclic pyrazoles were synthesized and structurally characterized. The compounds were evaluated for antimicrobial activity against selected bacterial and fungal strains, showing promising inhibitory effects. Molecular docking studies provided insights into binding interactions and structure–activity relationships ...
Dinkal V. Kasundra, Paresh N. Patel
wiley +1 more source
Recent advances in polymeric chemically amplified positive resists: Materials and design strategies
This review summarizes recent advances in the molecular design of positive chemically amplified resists, focusing on photoacid generators and polymer architectures. Key strategies for enhancing sensitivity—including self‐amplification effects, copolymerization of sensitive monomers, controlled polymerization, and photosensitized chemically amplified ...
Litao Zhou +3 more
wiley +1 more source
This review highlights recent advances in the use of organic carbonates, dimethyl carbonate (DMC), diethyl carbonate (DEC), and propylene carbonate (PC), as solvents in organic synthesis. Based on over seventy studies from the past 6 years, it shows their application in different organic reaction types, emphasizing their role in safer and more ...
Gabriela T. Quadros +5 more
wiley +1 more source
Abstract Background and aims Data on the presence of new psychoactive substances (NPS) mainly originate from drug‐checking, law enforcement and wastewater analysis sources, while data on NPS poisonings are scarce. In Europe, the documented incidence rate of NPS poisonings is highest in the Netherlands.
Johanna J. Nugteren‐van Lonkhuyzen +5 more
wiley +1 more source

