Results 1 to 10 of about 7,915 (201)
Whole Cells as Biocatalysts in Organic Transformations
Currently, the power and usefulness of biocatalysis in organic synthesis is undeniable, mainly due to the very high enantiomeric excess reached using enzymes, in an attempt to emulate natural processes.
Fabián Garzón-Posse +3 more
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Direct Transamidation Reactions: Mechanism and Recent Advances
Amides are undeniably some of the most important compounds in Nature and the chemical industry, being present in biomolecules, materials, pharmaceuticals and many other substances.
Paola Acosta-Guzmán +2 more
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The combination of transition metal catalysis and organocatalysis can afford both good reactivity and selectivity. Here, the authors present an α − propargylation of N-unprotected amino acid esters with propargylic alcohol derivatives via dual nickel and
Fang Zhu +5 more
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Asymmetric Organocatalysis with Chiral Covalent Organic Frameworks
Inspired by Mother Nature, the use of chiral covalent organic frameworks as heterogeneous asymmetric organocatalysts has arisen over the last decade as a new method in enantioselective synthesis.
Song-Chen Yu, Liang Cheng, Li Liu
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Asymmetric organocatalysis involving double activation
Asymmetric organocatalysis contributed tremendously to the field of organic synthesis since year 2000. Considering the diversity of organocatalysts and their activation modes, chemists developed the double activation strategy, in which two distinct ...
Zhi Chen +3 more
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Magnetic nanoparticle-supported organocatalysis
Magnetic nanoparticle (MNP)-supported catalysis is a new method to facilitate catalyst separation and reuse. This technique has recently been introduced for organocatalysis.
Huang Yibo, Zhang Wei
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One-Pot Synthesis of Dioxime Oxalates
Dioxime oxalates, a type of carbonyl oximes, are well-known as clean sources of iminyl radicals that undergo key organic chemistry transformations. A series of dioxime oxalates is reported in this manuscript, obtained by the reaction of the corresponding
Laura Adarve-Cardona +3 more
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Desymmetrization of N-Cbz glutarimides through N-heterocyclic carbene organocatalysis
Desymmetrization of achiral building blocks is one of the most efficient ways to access enantiopure compounds of synthetic relevance. Here, the authors desymmetrize glutarimides with alcohols via an imide C–N bond cleavage under NHC organocatalysis.
Zhouli Hu +12 more
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Non-Covalent Organocatalyzed Domino Reactions Involving Oxindoles: Recent Advances
The ubiquitous presence of spirooxindole architectures with several functionalities and stereogenic centers in bioactive molecules has been appealing for the development of novel methodologies seeking their preparation in high yields and selectivities ...
Tecla Gasperi +3 more
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Chirality is one of the most important attributes for its presence in a vast majority of bioactive natural products and pharmaceuticals. Asymmetric organocatalysis methods have emerged as a powerful methodology for the construction of highly ...
Zhonglei Wang
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