Results 1 to 10 of about 7,915 (201)

Whole Cells as Biocatalysts in Organic Transformations

open access: yesMolecules, 2018
Currently, the power and usefulness of biocatalysis in organic synthesis is undeniable, mainly due to the very high enantiomeric excess reached using enzymes, in an attempt to emulate natural processes.
Fabián Garzón-Posse   +3 more
doaj   +1 more source

Direct Transamidation Reactions: Mechanism and Recent Advances

open access: yesMolecules, 2018
Amides are undeniably some of the most important compounds in Nature and the chemical industry, being present in biomolecules, materials, pharmaceuticals and many other substances.
Paola Acosta-Guzmán   +2 more
doaj   +1 more source

Chiral aldehyde-nickel dual catalysis enables asymmetric α−propargylation of amino acids and stereodivergent synthesis of NP25302

open access: yesNature Communications, 2022
The combination of transition metal catalysis and organocatalysis can afford both good reactivity and selectivity. Here, the authors present an α − propargylation of N-unprotected amino acid esters with propargylic alcohol derivatives via dual nickel and
Fang Zhu   +5 more
doaj   +1 more source

Asymmetric Organocatalysis with Chiral Covalent Organic Frameworks

open access: yesOrganic Materials, 2021
Inspired by Mother Nature, the use of chiral covalent organic frameworks as heterogeneous asymmetric organocatalysts has arisen over the last decade as a new method in enantioselective synthesis.
Song-Chen Yu, Liang Cheng, Li Liu
doaj   +1 more source

Asymmetric organocatalysis involving double activation

open access: yesTetrahedron Chem, 2022
Asymmetric organocatalysis contributed tremendously to the field of organic synthesis since year 2000. Considering the diversity of organocatalysts and their activation modes, chemists developed the double activation strategy, in which two distinct ...
Zhi Chen   +3 more
doaj   +1 more source

Magnetic nanoparticle-supported organocatalysis

open access: yesGreen Processing and Synthesis, 2013
Magnetic nanoparticle (MNP)-supported catalysis is a new method to facilitate catalyst separation and reuse. This technique has recently been introduced for organocatalysis.
Huang Yibo, Zhang Wei
doaj   +1 more source

One-Pot Synthesis of Dioxime Oxalates

open access: yesMolbank, 2022
Dioxime oxalates, a type of carbonyl oximes, are well-known as clean sources of iminyl radicals that undergo key organic chemistry transformations. A series of dioxime oxalates is reported in this manuscript, obtained by the reaction of the corresponding
Laura Adarve-Cardona   +3 more
doaj   +1 more source

Desymmetrization of N-Cbz glutarimides through N-heterocyclic carbene organocatalysis

open access: yesNature Communications, 2022
Desymmetrization of achiral building blocks is one of the most efficient ways to access enantiopure compounds of synthetic relevance. Here, the authors desymmetrize glutarimides with alcohols via an imide C–N bond cleavage under NHC organocatalysis.
Zhouli Hu   +12 more
doaj   +1 more source

Non-Covalent Organocatalyzed Domino Reactions Involving Oxindoles: Recent Advances

open access: yesMolecules, 2017
The ubiquitous presence of spirooxindole architectures with several functionalities and stereogenic centers in bioactive molecules has been appealing for the development of novel methodologies seeking their preparation in high yields and selectivities ...
Tecla Gasperi   +3 more
doaj   +1 more source

Advances in the Asymmetric Total Synthesis of Natural Products Using Chiral Secondary Amine Catalyzed Reactions of α,β-Unsaturated Aldehydes

open access: yesMolecules, 2019
Chirality is one of the most important attributes for its presence in a vast majority of bioactive natural products and pharmaceuticals. Asymmetric organocatalysis methods have emerged as a powerful methodology for the construction of highly ...
Zhonglei Wang
doaj   +1 more source

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