Results 21 to 30 of about 6,799 (217)

Whole Cells as Biocatalysts in Organic Transformations

open access: yesMolecules, 2018
Currently, the power and usefulness of biocatalysis in organic synthesis is undeniable, mainly due to the very high enantiomeric excess reached using enzymes, in an attempt to emulate natural processes.
Fabián Garzón-Posse   +3 more
doaj   +1 more source

On Rational Design of Stereodivergent Organocatalysis Controlled by Selective Hydration

open access: yes, 2023
Stereodivergent asymmetric synthesis via slightly tuning the catalytic conditions is very attractive for early-stage drug discovery, because it is a very time efficient and economical method for obtaining all potential biologically active diastereomers ...
Liuqun, Gu
core   +1 more source

Understanding chiral proton organocatalysis using cinchonium derivatives

open access: yes, 2023
This work presents a detailed mechanistic study of a quininium-catalyzed aza-Michael reaction, providing essential infor-mation for the development of reactions in chiral proton organocatalysis (CPO).
Raquel, P. Herrera   +4 more
core   +1 more source

Direct Transamidation Reactions: Mechanism and Recent Advances

open access: yesMolecules, 2018
Amides are undeniably some of the most important compounds in Nature and the chemical industry, being present in biomolecules, materials, pharmaceuticals and many other substances.
Paola Acosta-Guzmán   +2 more
doaj   +1 more source

Why Organocatalysis?

open access: yesCHIMIA, 2007
Alexandre Alexakis
doaj   +2 more sources

Peptide catalyzed conjugate addition reactions of aldehydes to nitroolefins [PDF]

open access: yes, 2013
In this thesis mechanistic investigations into the peptide catalyzed conjugate addition reaction between aldehydes and nitroolefins are described.
Duschmalé, Jörg
core   +1 more source

Chiral aldehyde-nickel dual catalysis enables asymmetric α−propargylation of amino acids and stereodivergent synthesis of NP25302

open access: yesNature Communications, 2022
The combination of transition metal catalysis and organocatalysis can afford both good reactivity and selectivity. Here, the authors present an α − propargylation of N-unprotected amino acid esters with propargylic alcohol derivatives via dual nickel and
Fang Zhu   +5 more
doaj   +1 more source

Asymmetric Organocatalysis with Chiral Covalent Organic Frameworks

open access: yesOrganic Materials, 2021
Inspired by Mother Nature, the use of chiral covalent organic frameworks as heterogeneous asymmetric organocatalysts has arisen over the last decade as a new method in enantioselective synthesis.
Song-Chen Yu, Liang Cheng, Li Liu
doaj   +1 more source

Asymmetric organocatalysis involving double activation

open access: yesTetrahedron Chem, 2022
Asymmetric organocatalysis contributed tremendously to the field of organic synthesis since year 2000. Considering the diversity of organocatalysts and their activation modes, chemists developed the double activation strategy, in which two distinct ...
Zhi Chen   +3 more
doaj   +1 more source

Magnetic nanoparticle-supported organocatalysis

open access: yesGreen Processing and Synthesis, 2013
Magnetic nanoparticle (MNP)-supported catalysis is a new method to facilitate catalyst separation and reuse. This technique has recently been introduced for organocatalysis.
Huang Yibo, Zhang Wei
doaj   +1 more source

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