Results 11 to 20 of about 6,799 (217)
Organocatalysis Chemistry in Flow
Current Organocatalysis, 2015 The last decade has witnessed a huge growth in the use of flow chemistry as wellestablished procedure for performing chemical transformations; indeed, under continuous flow conditions, more sustainable, safer and easier scalable processes could be developed with respect to conventional batch procedures.
A. Puglisi +3 more
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Theoretical Perspectives in Organocatalysis
Chemistry – A European Journal, 2022 AbstractIt is clear that the field of organocatalysis is continuously expanding during the last decades. With increasing computational capacity and new techniques, computational methods have provided a more economic approach to explore different chemical systems.
Nika Melnyk +3 more
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Do We Need Asymmetric Organocatalysis?
CHIMIA, 2007 Asymmetric organocatalysis is a 'fast lane' of the chemical highway: the progress in the last decade is simply spectacular. This introductory article summarizes basic principles, historical background, and discusses basic catalyst classes and ...
Peter I. Dalko
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Chiral (Stereoselective) Drugs, Asymmetric Synthesis, and Racemic Resolution Methods. [PDF]
ChiralityChirality is crucial in drug development since both biological targets in the organism and the majority of pharmaceutical compounds are chiral. The synthesis and resolution of chiral compounds are critical steps while developing chiral drugs. Asymmetric synthesis and racemic resolution are the two most common methods for obtaining enantiopure drugs ...
Karayavuz B, Kirmizioglu CK.
europepmc +2 more sources
Phosphine Organocatalysis [PDF]
Chemical Reviews, 2018 The hallmark of nucleophilic phosphine catalysis is the initial nucleophilic addition of a phosphine to an electrophilic starting material, producing a reactive zwitterionic intermediate, generally under mild conditions. In this Review, we classify nucleophilic phosphine catalysis reactions in terms of their electrophilic components. In the majority of
Hongchao Guo +4 more
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Organocatalysis emerging as a technology [PDF]
, 2021 During the last 20 years, organocatalysis has significantly advanced as a field. Thanks to contributions from hundreds of groups and companies around the world, the area has risen from a few mechanistically ill-defined niche reactions, to one of the most
List, B., Aukland, M.
core +1 more source
Molecules, 2023 Through the lens of organocatalysis and phase transfer catalysis, we will examine the key components to calculate or predict catalysis-performance metrics, such as turnover frequency and measurement of stereoselectivity, via computational chemistry.
Choon Wee Kee
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Synergistic Organo‐Organocatalysis
, 2023 Asymmetric organocatalysis is pivotal in the field of asymmetric catalysis and is a crucial technology platform in the industry. However, in some cases, catalysis may have reached its limit and synergistic catalysis is an interesting groundbreaking ...
Pesciaioli, Fabio +3 more
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Halogen-Bond-Based Organocatalysis Unveiled: Computational Design and Mechanistic Insights
, 2023 Halogen-bond-based organocatalysis is a promising alternative to the extensively explored halogen-bond-based catalysis. This paper presents a comprehensive theoreti- cal investigation of the structural and electronic properties of the σ-hole, as well as ...
Nika, Melnyk +2 more
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Educación Química, 2018 Solvent-free asymmetric organocatalyzed reactions: a strategy towards a greener organocatalysis According with the principles of “green” chemistry, asymmetric organocatalysis aims to become a sustainable strategy to catalyze a wide range of chemical ...
José G. Hernández, Eusebio Juaristi
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