The Emergence of Quinone Methides in Asymmetric Organocatalysis [PDF]
Quinone methides (QMs) are highly reactive compounds that have been defined as “elusive” intermediates, or even as a “synthetic enigma” in organic chemistry.
Lorenzo Caruana +2 more
doaj +7 more sources
Palladium and Organocatalysis: An Excellent Recipe for Asymmetric Synthesis [PDF]
The dual activation of simple substrates by the combination of organocatalysis and palladium catalysis has been successfully applied in a variety of different asymmetric transformations.
Isidro M. Pastor +3 more
doaj +9 more sources
Advances in asymmetric organocatalysis over the last 10 years [PDF]
Organocatalysis has become a major pillar of (asymmetric) catalysis. Here, the authors discuss recent trends in organocatalytic activation modes for challenging stereoselective transformations and the emerging integration with other fields, such as ...
Shao-Hua Xiang, Bin Tan
doaj +3 more sources
Mechanochemistry assisted asymmetric organocatalysis: A sustainable approach [PDF]
Ball-milling and pestle and mortar grinding have emerged as powerful methods for the development of environmentally benign chemical transformations. Recently, the use of these mechanochemical techniques in asymmetric organocatalysis has increased.
Pankaj Chauhan, Swapandeep Singh Chimni
doaj +3 more sources
Evolution of design approaches in asymmetric organocatalysis over the last decade
This perspective intends to cover the vast field of asymmetric organocatalysis and its evolution during the last ten years. This work has evaluated the corresponding timeline of the progression of the field concerning the main synthetic approaches as ...
Nika Melnyk +3 more
doaj +4 more sources
New advances in asymmetric organocatalysis [PDF]
Radovan Šebesta
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Asymmetric Organocatalysis: A Survival Guide to Medicinal Chemists [PDF]
Majority of drugs act by interacting with chiral counterparts, e.g., proteins, and we are, unfortunately, well-aware of how chirality can negatively impact the outcome of a therapeutic regime.
Efraim Reyes +2 more
doaj +2 more sources
Beyond canonical asymmetric induction in phosphine organocatalysis [PDF]
Phosphine organocatalysis has emerged as a formidable and transformative platform for engineering reaction manifolds that depart from classical models of asymmetric induction, enabling cascade cyclizations to proceed through distinctive stereoelectronic ...
Archana Vijayakumar +4 more
doaj +2 more sources
Enantioselective cyclization reactions involving 3-isothiocyanato oxindoles: synthesis of spirocycles [PDF]
Recently, 3-isothiocyanato oxindoles have been used in various asymmetric cascade cyclization reactions for the synthesis of biologically important spirocyclic compounds.
Mohammad Hadi Edareh +4 more
doaj +2 more sources
Enantioselective radical chemistry: a bright future ahead [PDF]
This perspective is focused on enantioselective free radical reactions. It describes several important catalytic asymmetric strategies applied to enantioselective radical reactions, including chiral Lewis acid catalysis, organocatalysis, photoredox ...
Anna C. Renner +3 more
doaj +2 more sources

