Advances in asymmetric organocatalysis over the last 10 years [PDF]
Nature Communications, 2020 Organocatalysis has become a major pillar of (asymmetric) catalysis. Here, the authors discuss recent trends in organocatalytic activation modes for challenging stereoselective transformations and the emerging integration with other fields, such as ...
Bin Tan, Shaohua Xiang, Tan Bin
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The Emergence of Quinone Methides in Asymmetric Organocatalysis [PDF]
Molecules, 2015 Quinone methides (QMs) are highly reactive compounds that have been defined as “elusive” intermediates, or even as a “synthetic enigma” in organic chemistry.
Mariafrancesca Fochi, Luca Bernardi
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Mechanochemistry assisted asymmetric organocatalysis: A sustainable approach [PDF]
Beilstein Journal of Organic Chemistry, 2012 Ball-milling and pestle and mortar grinding have emerged as powerful methods for the development of environmentally benign chemical transformations. Recently, the use of these mechanochemical techniques in asymmetric organocatalysis has increased.
Pankaj Chauhan, Swapandeep Singh Chimni
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Evolution of design approaches in asymmetric organocatalysis over the last decade [PDF]
Tetrahedron Chem, 2023 This perspective intends to cover the vast field of asymmetric organocatalysis and its evolution during the last ten years. This work has evaluated the corresponding timeline of the progression of the field concerning the main synthetic approaches as ...
Cristina Trujillo +2 more
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Asymmetric Organocatalysis: A Survival Guide to Medicinal Chemists [PDF]
Molecules, 2022 Majority of drugs act by interacting with chiral counterparts, e.g., proteins, and we are, unfortunately, well-aware of how chirality can negatively impact the outcome of a therapeutic regime.
Efraim Reyes +2 more
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New advances in asymmetric organocatalysis [PDF]
Beilstein Journal of Organic Chemistry, 2022 Radovan Šebesta
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Palladium and Organocatalysis: An Excellent Recipe for Asymmetric Synthesis [PDF]
Molecules, 2013 The dual activation of simple substrates by the combination of organocatalysis and palladium catalysis has been successfully applied in a variety of different asymmetric transformations.
BEATRIZ Macià +2 more
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Chiral (Stereoselective) Drugs, Asymmetric Synthesis, and Racemic Resolution Methods. [PDF]
ChiralityChirality is crucial in drug development since both biological targets in the organism and the majority of pharmaceutical compounds are chiral. The synthesis and resolution of chiral compounds are critical steps while developing chiral drugs. Asymmetric synthesis and racemic resolution are the two most common methods for obtaining enantiopure drugs ...
Karayavuz B, Kirmizioglu CK.
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Enantioselective radical chemistry: a bright future ahead [PDF]
Beilstein Journal of Organic ChemistryThis perspective is focused on enantioselective free radical reactions. It describes several important catalytic asymmetric strategies applied to enantioselective radical reactions, including chiral Lewis acid catalysis, organocatalysis, photoredox ...
Anna C. Renner +3 more
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Enantioselective cyclization reactions involving 3-isothiocyanato oxindoles: synthesis of spirocycles [PDF]
RSC AdvancesRecently, 3-isothiocyanato oxindoles have been used in various asymmetric cascade cyclization reactions for the synthesis of biologically important spirocyclic compounds.
Mohammad Hadi Edareh +4 more
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