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The Emergence of Quinone Methides in Asymmetric Organocatalysis [PDF]

open access: yesMolecules, 2015
Quinone methides (QMs) are highly reactive compounds that have been defined as “elusive” intermediates, or even as a “synthetic enigma” in organic chemistry.
Lorenzo Caruana   +2 more
doaj   +7 more sources

Palladium and Organocatalysis: An Excellent Recipe for Asymmetric Synthesis [PDF]

open access: yesMolecules, 2013
The dual activation of simple substrates by the combination of organocatalysis and palladium catalysis has been successfully applied in a variety of different asymmetric transformations.
Isidro M. Pastor   +3 more
doaj   +9 more sources

Advances in asymmetric organocatalysis over the last 10 years [PDF]

open access: yesNature Communications, 2020
Organocatalysis has become a major pillar of (asymmetric) catalysis. Here, the authors discuss recent trends in organocatalytic activation modes for challenging stereoselective transformations and the emerging integration with other fields, such as ...
Shao-Hua Xiang, Bin Tan
doaj   +3 more sources

Mechanochemistry assisted asymmetric organocatalysis: A sustainable approach [PDF]

open access: yesBeilstein Journal of Organic Chemistry, 2012
Ball-milling and pestle and mortar grinding have emerged as powerful methods for the development of environmentally benign chemical transformations. Recently, the use of these mechanochemical techniques in asymmetric organocatalysis has increased.
Pankaj Chauhan, Swapandeep Singh Chimni
doaj   +3 more sources

Evolution of design approaches in asymmetric organocatalysis over the last decade

open access: yesTetrahedron Chem, 2023
This perspective intends to cover the vast field of asymmetric organocatalysis and its evolution during the last ten years. This work has evaluated the corresponding timeline of the progression of the field concerning the main synthetic approaches as ...
Nika Melnyk   +3 more
doaj   +4 more sources

Asymmetric Organocatalysis: A Survival Guide to Medicinal Chemists [PDF]

open access: yesMolecules, 2022
Majority of drugs act by interacting with chiral counterparts, e.g., proteins, and we are, unfortunately, well-aware of how chirality can negatively impact the outcome of a therapeutic regime.
Efraim Reyes   +2 more
doaj   +2 more sources

Beyond canonical asymmetric induction in phosphine organocatalysis [PDF]

open access: yesRSC Advances
Phosphine organocatalysis has emerged as a formidable and transformative platform for engineering reaction manifolds that depart from classical models of asymmetric induction, enabling cascade cyclizations to proceed through distinctive stereoelectronic ...
Archana Vijayakumar   +4 more
doaj   +2 more sources

Enantioselective cyclization reactions involving 3-isothiocyanato oxindoles: synthesis of spirocycles [PDF]

open access: yesRSC Advances
Recently, 3-isothiocyanato oxindoles have been used in various asymmetric cascade cyclization reactions for the synthesis of biologically important spirocyclic compounds.
Mohammad Hadi Edareh   +4 more
doaj   +2 more sources

Enantioselective radical chemistry: a bright future ahead [PDF]

open access: yesBeilstein Journal of Organic Chemistry
This perspective is focused on enantioselective free radical reactions. It describes several important catalytic asymmetric strategies applied to enantioselective radical reactions, including chiral Lewis acid catalysis, organocatalysis, photoredox ...
Anna C. Renner   +3 more
doaj   +2 more sources

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