Results 1 to 10 of about 7,117 (203)

New advances in asymmetric organocatalysis [PDF]

Beilstein Journal of Organic Chemistry, 2022
Radovan Šebesta
doaj   +5 more sources

New advances in asymmetric organocatalysis II [PDF]

Beilstein Journal of Organic Chemistry
Radovan Šebesta
doaj   +4 more sources

Asymmetric Organocatalysis: A Survival Guide to Medicinal Chemists [PDF]

Molecules, 2022
Majority of drugs act by interacting with chiral counterparts, e.g., proteins, and we are, unfortunately, well-aware of how chirality can negatively impact the outcome of a therapeutic regime.
Efraim Reyes, Liher Prieto, Andrea Milelli   +2 more
doaj   +2 more sources

Advances in asymmetric organocatalysis over the last 10 years [PDF]

Nature Communications, 2020
Organocatalysis has become a major pillar of (asymmetric) catalysis. Here, the authors discuss recent trends in organocatalytic activation modes for challenging stereoselective transformations and the emerging integration with other fields, such as ...
Shao-Hua Xiang, Bin Tan
doaj   +2 more sources

Enantiopurity-Dependent Peptide Coacervates and Asymmetric Organocatalysis. [PDF]

Small
Enantiopure peptide LLLPFF‐OCH3 forms liquid–liquid phase‐separated (LLPS) droplets that act as chiral microreactors for enantioselective aldol catalysis. Racemic mixtures fail to undergo LLPS, showing spontaneous enantiomeric self‐disproportionation (SDE).
Vetrano A, Fonte ND, Monasson O, Perrella F, Porco M, Mercuri F, Dell'Orletta G, Petragnano F, Carioscia A, Deodato D, Calcagno D, Salvitti G, Reale S, Pesciaioli F, Ferrante C, Tedeschi D, Grasso G, Benassi P, Peroni E, Carlone A, Daidone I, Iacobucci C.   +21 more
europepmc   +2 more sources

Mechanochemistry assisted asymmetric organocatalysis: A sustainable approach [PDF]

Beilstein Journal of Organic Chemistry, 2012
Ball-milling and pestle and mortar grinding have emerged as powerful methods for the development of environmentally benign chemical transformations. Recently, the use of these mechanochemical techniques in asymmetric organocatalysis has increased.
Pankaj Chauhan, Swapandeep Singh Chimni
doaj   +2 more sources

Recent Advances in Asymmetric Organocatalyzed Conjugate Additions to Nitroalkenes [PDF]

Molecules, 2017
The asymmetric conjugate addition of carbon and heteroatom nucleophiles to nitroalkenes is a very interesting tool for the construction of highly functionalized synthetic building blocks.
Diego A. Alonso, Alejandro Baeza, Rafael Chinchilla, Cecilia Gómez, Gabriela Guillena, Isidro M. Pastor, Diego J. Ramón   +6 more
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The Emergence of Quinone Methides in Asymmetric Organocatalysis [PDF]

Molecules, 2015
Quinone methides (QMs) are highly reactive compounds that have been defined as “elusive” intermediates, or even as a “synthetic enigma” in organic chemistry.
Lorenzo Caruana, Mariafrancesca Fochi, Luca Bernardi   +2 more
doaj   +2 more sources

Enantioselective radical chemistry: a bright future ahead [PDF]

Beilstein Journal of Organic Chemistry
This perspective is focused on enantioselective free radical reactions. It describes several important catalytic asymmetric strategies applied to enantioselective radical reactions, including chiral Lewis acid catalysis, organocatalysis, photoredox ...
Anna C. Renner, Sagar S. Thorat, Hariharaputhiran Subramanian, Mukund P. Sibi   +3 more
doaj   +2 more sources

Evolution of design approaches in asymmetric organocatalysis over the last decade

Tetrahedron Chem, 2023
This perspective intends to cover the vast field of asymmetric organocatalysis and its evolution during the last ten years. This work has evaluated the corresponding timeline of the progression of the field concerning the main synthetic approaches as ...
Nika Melnyk, Marianne Rica Garcia, Iñigo Iribarren, Cristina Trujillo   +3 more
doaj   +1 more source