Results 1 to 10 of about 2,677,083 (277)

Intramolecular Nickel-Catalyzed Reductive Coupling: Enantioselective Synthesis of Tetrahydroisoquinolines and Related Heterocycles. [PDF]

Angew Chem Int Ed Engl
The successful extension of the nickel‐catalyzed asymmetric coupling of polarized 1,3‐dienes with aldehydes to an intramolecular setting opens an efficient new entry into hydroxylated N‐heterocyclic compounds, most notably valuable tetrahydroisoquinolines.
Bender T, Leutzsch M, Sell Y, Fürstner A.   +3 more
europepmc   +3 more sources

A FACILE SYNTHESIS OF (S) – (-) – PROPRANOLOL [PDF]

Journal of Sciences, Islamic Republic of Iran, 2003
A one-pot synthesis of (S)-(-)-propranolol is reported. Zn(NO3)2/(+)-tartaric acid catalyzed enantioselective synthesis of (S)-(-)-propranolol via kinetic resolution of key intermediate ?-naphthyl glycidyl ether with high optical and chemical yield.
doaj  

Enantioselective Synthesis of Oxazocines via MQ‐Phos Enabled Palladium‐Catalyzed Asymmetric Formal [4+4]‐Cycloadditions

Advanced Science
Oxazocines are key structural intermediates in the synthesis of natural products and pharmaceutical molecules. However, the synthesis of oxazocines especially in a highly enantioselective manner, is a long‐standing formidable challenge due to unfavorable
Qiaojing Meng, Yinggao Meng, Qinglin Liu, Bing Yu, Zhong‐Jun Li, Er‐Qing Li, Junliang Zhang   +6 more
doaj   +1 more source

Enantioselective synthesis of chiral

Green Synthesis and Catalysis
The C–N axial chirality is widely present in natural products, bioactive molecules, and chiral ligands. Catalytic asymmetric construction of C–N axially chiral compounds is a challenging task due to the lower rotational barriers of the C–N bond. Here, we
Zi-Wei He, Dong Liang, Jia-Rong Chen, Ying Cheng, Wen-Jing Xiao   +4 more
doaj   +1 more source

Applications of Nanozymes in Chiral-Molecule Recognition through Electrochemical and Ultraviolet–Visible Analysis

Molecules
Chiral molecules have similar physicochemical properties, which are different in terms of physiological activities and toxicities, rendering their differentiation and recognition highly significant. Nanozymes, which are nanomaterials with inherent enzyme-
Jing-Jing Dai, Guo-Ying Chen, Lei Xu, Huan Zhu, Feng-Qing Yang   +4 more
doaj   +1 more source

Catalytic Enantioselective Syntheses of Sulfinamidines From Sulfenamides

ChemistryEurope
Sulfinamidines are sulfur(IV) functional groups with significant medicinal potential and serve as versatile intermediates toward sulfur(VI) motifs, which are also of heightened pharmaceutical interest.
Fumito Saito
doaj   +1 more source

Catalytic Asymmetric Cyclizative Rearrangement of Anilines and Vicinal Diketones to Access 2,2‐Disubstituted Indolin‐3‐ones

Advanced Science
The efficient synthesis of chiral 2,2‐disubstituted indolin‐3‐ones is of great importance due to its significant synthetic and biological applications. However, catalytic enantioselective methods for de novo synthesis of such heterocycles remain scarce ...
Rui Quan, Xing‐Zi Li, Zi‐Qi Wang, Yu‐Ping He, Hua Wu   +4 more
doaj   +1 more source

Enantioselective Catalysis for Agrochemicals: The Case History of the DUAL MAGNUM® Herbicide

CHIMIA, 1997
The use of enantioselective catalytic methods for the technical preparation of chiral agrochemicals is illustrated by the case history of the herbicide (S)-merolachlor (trade name DUAL MAGNUM®).
Hans-Ulrich Blaser, Felix Spindler
doaj   +2 more sources

Multiple Atropo Selectivity by κ2‐N,O‐Oxazoline Urea Ligands in Cobaltaelectro‐Catalyzed C─H Activations: Decoding Selectivity with Data Science Integration

ChemistryEurope
Enantioselective catalysis is one of the most prominent strategies in organic synthesis to access chiral bioactive compounds and advanced organic materials.
Philipp Boos, Neeraj Kumar Pandit, Suman Dana, Tristan von Münchow, Airu Hashidoko, Laura Haberstock, Regine Herbst‐Irmer, Dietmar Stalke, Lutz Ackermann   +8 more
doaj   +1 more source

Advances in Enantioselective Synthesis and Chiral Resolution of Insecticides. [PDF]

Molecules
López-Rosas CA, Delgado-Alvarado E, Barrera-Méndez F, Bonilla-Landa I, Olivares-Romero JL.   +4 more
europepmc   +1 more source