Results 11 to 20 of about 14,649 (249)
Enantioselective synthesis of (−)-paeonilide [PDF]
Chemical Communications, 2012 The first enantioselective synthesis of (−)-paeonilide is reported. Starting from inexpensive furan-3-carboxylic acid the targeted monoterpene was obtained in 12 steps via an asymmetric cyclopropanation-lactonization cascade and a stereoselective side chain insertion at an acetal-like position.
Harrar, Klaus, Reiser, Oliver
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Enantioselective Synthesis of (−)-Acetylapoaranotin
Organic Letters, 2017 The first enantioselective total synthesis of the epipolythiodiketopiperazine (ETP) natural product (-)-acetylapoaranotin (3) is reported. The concise synthesis was enabled by an eight-step synthesis of a key cyclohexadienol-containing amino ester building block.
Haoxuan Wang +5 more
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Enantioselective Synthesis of Azamerone [PDF]
Journal of the American Chemical Society, 2018 A concise and selective synthesis of the dichlorinated meroterpenoid azamerone is described. The paucity of tactics for the synthesis of chiral organochlorides motivated the development of unique strategies for accessing these motifs in enantioenriched forms.
Matthew L. Landry +2 more
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Alilação e crotilação catalítica e enantiosseletiva de aldeídos
Química Nova, 2006 The field of chiral catalysis has experienced explosive growth over the last two decades. By now, many of the classical reactions in organic synthesis can be carried out efficiently in asymmetric manner.
Fátima Ângelo de +2 more
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iScience, 2019 Summary: The direct functionalization of C(sp3)-H bonds has led to the development of methods to access molecules or intermediates from basic chemicals in an atom- and step-economic fashion.
Cheng-Yu Wang +5 more
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Beilstein Journal of Organic Chemistry, 2013 A concise enantioselective synthesis of the advanced intermediate 5 for the synthesis of pumiliotoxins (Gallagher’s intermediate) is described. The synthesis started from the regio- and trans-diastereoselective (dr = 98:2) reductive 3-butenylation of (R)-
Jie Zhang +2 more
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Enantioselective Synthesis of cis-Decalins Using Organocatalysis and Sulfonyl Nazarov Reagents
Molecules, 2015 The first organocatalytic synthesis of cis-decalins using sulfonyl Nazarov reagents is reported. The Jørgensen’s catalyst directs this highly enantioselective synthesis using different cyclohexenal derivatives.
Javier Peña +6 more
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Enantioselective Synthesis of (−)-Basiliskamide A [PDF]
Organic Letters, 2012 Basiliskamide A is an antifungal polyketide natural product isolated by Andersen and co-workers from a Bacillus laterosporus isolate, PNG-276. A nine-step enantioselective synthesis of (-)-basiliskamide A is reported, starting from commercially available β-hydroxy ester 7.
Ming, Chen, William R, Roush
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Chromium(II)-catalyzed enantioselective arylation of ketones
Beilstein Journal of Organic Chemistry, 2016 The chromium-catalyzed enantioselective addition of carbo halides to carbonyl compounds is an important transformation in organic synthesis. However, the corresponding catalytic enantioselective arylation of ketones has not been reported to date. Herein,
Gang Wang +4 more
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Beilstein Journal of Organic Chemistry, 2021 A procedure for the enantioselective synthesis of α-substituted glutamates and pyroglutamates via a cyclopropenimine-catalyzed Michael addition of amino ester imines is described.
Zara M. Seibel +2 more
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