Results 21 to 30 of about 67,862 (282)
Enantioselective synthesis of (−)-paeonilide [PDF]
Chemical Communications, 2012 The first enantioselective synthesis of (−)-paeonilide is reported. Starting from inexpensive furan-3-carboxylic acid the targeted monoterpene was obtained in 12 steps via an asymmetric cyclopropanation-lactonization cascade and a stereoselective side chain insertion at an acetal-like position.
Harrar, Klaus, Reiser, Oliver
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Hydrazones as Singular Reagents in Asymmetric Organocatalysis [PDF]
, 2016 This Minireview summarizes strategies and developments regarding the use of hydrazones as reagents in asymmetric organocatalysis, their distinct roles in nucleophile–electrophile, cycloaddition, and cyclization reactions.
Fernández Fernández, Rosario Fátima +4 more
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Enantioselective Synthesis of (−)-Acetylapoaranotin
Organic Letters, 2017 The first enantioselective total synthesis of the epipolythiodiketopiperazine (ETP) natural product (-)-acetylapoaranotin (3) is reported. The concise synthesis was enabled by an eight-step synthesis of a key cyclohexadienol-containing amino ester building block.
Haoxuan Wang +5 more
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Enantioselective Total Synthesis of (+)-Cassiol [PDF]
, 2009 An enantioselective total synthesis of (+)-cassiol is reported. The complex derived from Pd-2(pmdba)(3) and enantiopure t-BuPHOX ligand catalyzes enantioconvergent decarboxylative alkylation to generate the quaternary carbon stereocenter at an early ...
Mohr, Justin T. +2 more
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Enantioselective Total Synthesis of (+)‐Tricycloclavulone. [PDF]
ChemInform, 2004 The first total synthesis of (+)-tricycloclavulone having a unique tricyclo[5,3,0,01,4]decane skeleton and six chiral centers was achieved in a highly stereoselective manner. It includes a catalytic enantioselective [2+2]-cycloaddition reaction using novel chiral copper catalyst, extremely effecting an intramolecular ester transfer reaction, and ...
Hisanaka, Ito +4 more
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iScience, 2019 Summary: The direct functionalization of C(sp3)-H bonds has led to the development of methods to access molecules or intermediates from basic chemicals in an atom- and step-economic fashion.
Cheng-Yu Wang +5 more
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Beilstein Journal of Organic Chemistry, 2013 A concise enantioselective synthesis of the advanced intermediate 5 for the synthesis of pumiliotoxins (Gallagher’s intermediate) is described. The synthesis started from the regio- and trans-diastereoselective (dr = 98:2) reductive 3-butenylation of (R)-
Jie Zhang +2 more
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Enantioselective Total Synthesis of (+)-Jasplakinolide [PDF]
Organic Letters, 2007 AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Arun K, Ghosh, Deuk Kyu, Moon
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Enantioselective Synthesis of cis-Decalins Using Organocatalysis and Sulfonyl Nazarov Reagents
Molecules, 2015 The first organocatalytic synthesis of cis-decalins using sulfonyl Nazarov reagents is reported. The Jørgensen’s catalyst directs this highly enantioselective synthesis using different cyclohexenal derivatives.
Javier Peña +6 more
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Enantioselective Total Synthesis of (+)‐Obtusenyne. [PDF]
ChemInform, 2003 A total synthesis of the laurencia metabolite (+)-obtusenyne has been completed. The key steps include a Sharpless kinetic resolution and an asymmetric glycolate alkylation to establish the stereogenic centers adjacent to the ether linkage and a ring-closing metathesis reaction to construct the nine-membered ether without the aid of a cyclic ...
Michael T, Crimmins, Mark T, Powell
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