Results 21 to 30 of about 2,677,083 (277)
Nature Communications, 2023 The primary objective in synthetic organic chemistry is to develop highly efficient, selective, and versatile synthetic methodologies, which are essential for discovering new drug candidates and agrochemicals. In this study, we present a unified strategy
Fang-Fang Xu +3 more
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Enantioselective synthesis of (−)-paeonilide [PDF]
Chemical Communications, 2012 The first enantioselective synthesis of (−)-paeonilide is reported. Starting from inexpensive furan-3-carboxylic acid the targeted monoterpene was obtained in 12 steps via an asymmetric cyclopropanation-lactonization cascade and a stereoselective side chain insertion at an acetal-like position.
Klaus, Harrar, Oliver, Reiser
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Challenging Atroposelective C–H Arylation
SynOpen, 2020 Atropisomeric molecules are privileged scaffolds, not only as ligands for asymmetric synthesis, but also as biologically active products and advanced materials.
Joanna Wencel-Delord +1 more
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A Catalytic Highly Enantioselective Synthesis of Spirooxazolines [PDF]
, 2021 A catalytic highly enantioselective synthesis of spirooxazolines is presented. Starting from readily available 2-naphthol-substituted benzamides and using catalytic amounts of a chiral triazole-substituted iodoarene catalyst, a variety of spirooxazolines
Ayham, Abazid, Boris, Nachtsheim
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Total synthesis of (-)-pyridovericin and synthetic studies towards aetheramide B [PDF]
, 2015 In this thesis, two projects involving the total synthesis of natural products are presented. The first part gives an overview on neurodegenerative diseases and introduces the neuritogenic pyridopolyene natural product (–)-pyridovericin.
Schmid, Fabian Felix
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Enantioselective Synthesis of (−)-Basiliskamide A [PDF]
Organic Letters, 2012 Basiliskamide A is an antifungal polyketide natural product isolated by Andersen and co-workers from a Bacillus laterosporus isolate, PNG-276. A nine-step enantioselective synthesis of (-)-basiliskamide A is reported, starting from commercially available β-hydroxy ester 7.
Ming, Chen, William R, Roush
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Enantioselective Synthesis of (−)-Acetylapoaranotin
Organic Letters, 2017 The first enantioselective total synthesis of the epipolythiodiketopiperazine (ETP) natural product (-)-acetylapoaranotin (3) is reported. The concise synthesis was enabled by an eight-step synthesis of a key cyclohexadienol-containing amino ester building block.
Haoxuan Wang +5 more
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Total Enantioselective Synthesis of a Norbornene Derivative via Lewis Acid Catalyzed Asymmetric Diels-Alder Reaction using the Oppolzer\u27s Camphorsultam as a Chiral Auxilary [PDF]
, 2023 In this paper, an efficient enantioselective synthesis of a norbornene derivative is described. Oppolzer\u27s chiral sultam-directed asymmetric Diels-alder [4+2] cycloaddition was conducted as a crucial tool to control the diastereoselectivity of the ...
Anissa, Yacin-Ali +3 more
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Alilação e crotilação catalítica e enantiosseletiva de aldeídos
Química Nova, 2006 The field of chiral catalysis has experienced explosive growth over the last two decades. By now, many of the classical reactions in organic synthesis can be carried out efficiently in asymmetric manner.
Fátima Ângelo de +2 more
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iScience, 2019 Summary: The direct functionalization of C(sp3)-H bonds has led to the development of methods to access molecules or intermediates from basic chemicals in an atom- and step-economic fashion.
Cheng-Yu Wang +5 more
doaj +1 more source