Results 21 to 30 of about 14,649 (249)
Total Enantioselective Synthesis of (‐)‐Cytisine. [PDF]
ChemInform, 2004 [reaction: see text] The first total enantiosynthesis of the biologically active alkaloid (-)-cytisine is reported, featuring a ruthenium-catalyzed RCM reaction as the key step. The approach relies on readily available cis-piperidine-3,5-dimethanol monoacetate as the chiral building block, and it is suited for achieving the target compound in both ...
B. Danieli +5 more
openaire +4 more sources
A Flexible Enantioselective Synthesis of the Isofurans. [PDF]
ChemInform, 2004 AbstractFor Abstract see ChemInform Abstract in Full Text.
Douglass F, Taber +2 more
openaire +2 more sources
Enantioselective Total Synthesis of Bistramide A [PDF]
Journal of the American Chemical Society, 2006 AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Michael T, Crimmins, Amy C, DeBaillie
openaire +3 more sources
Molecules, 2006 The enantioselective synthesis of the title compound, using Meyers' bicyclic lactam methodology, is described. This compound and a few of its derivatives are useful intermediates in natural product synthesis.
Pierre J. De Clercq +2 more
doaj +1 more source
Enantioselective Total Synthesis of (+)-Jasplakinolide [PDF]
Organic Letters, 2007 AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Arun K, Ghosh, Deuk Kyu, Moon
openaire +2 more sources
Nature CommunicationsN-bridged [3.2.1]octanes (tropanes) and their related bridged bicyclic systems constitute highly sought-after scaffolds in drug discovery and development.
Chao Fang +5 more
doaj +1 more source
Enantioselective Total Synthesis of (+)‐Obtusenyne. [PDF]
ChemInform, 2003 A total synthesis of the laurencia metabolite (+)-obtusenyne has been completed. The key steps include a Sharpless kinetic resolution and an asymmetric glycolate alkylation to establish the stereogenic centers adjacent to the ether linkage and a ring-closing metathesis reaction to construct the nine-membered ether without the aid of a cyclic ...
Michael T, Crimmins, Mark T, Powell
openaire +2 more sources
Directed evolution of enzymes at the crossroads of tradition and innovation
FEBS Open Bio, EarlyView.An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova +2 more
wiley +1 more source
Beilstein Journal of Organic ChemistryThe desymmetric enantioselective reduction of cyclic 1,3-dicarbonyl compounds is a powerful tool for the construction of ring systems bearing multiple stereocenters including all-carbon quaternary stereocenters, which are widely useful chiral building ...
Dong-Xing Tan, Fu-She Han
doaj +1 more source
Advanced Functional Materials, EarlyView.Enzyme‐loaded Fe3+‐modified polydopamine microparticles (Fe3+‐PD) act as hybrid biocatalytic frameworks demonstrating NADH peroxidase‐mimic catalytic activities, operation of biocatalytic cascades in confined media, and enantioselective oxidation of D/L‐DOPA. ABSTRACT We report on the synthesis of Fe3+‐modified porous polydopamine microparticles acting
Liubing Kong +6 more
wiley +1 more source