Results 41 to 50 of about 67,862 (282)
Enantioselective Total Synthesis of FR900482 [PDF]
The Journal of Organic Chemistry, 2004 The development of two approaches for the enantioselective total synthesis of FR900482 is described. A precursor for the formation of the benzazocine ring was assembled effectively by a modification of the Sonogashira coupling of an aryl triflate with a chiral acetylene unit derived from tartaric acid and the subsequent novel ketone formation via ...
Masashi, Suzuki +3 more
openaire +2 more sources
Angewandte Chemie, EarlyView.Metal‐catalyzed enantioconvergent substitutions of unactivated cyclic electrophiles by organometallic nucleophiles have not previously been reported. Herein, a chiral nickel catalyst is described that achieves this objective, coupling 3‐iodopyrrolidine derivatives with arylzinc nucleophiles.
Ting Hei Matthew Wong +2 more
wiley +2 more sources
Oxidative Heck desymmetrisation of 2,2-disubstituted cyclopentene-1,3-diones [PDF]
, 2015 Oxidative Heck couplings have been successfully developed for 2,2-disubstituted cyclopentene-1,3-diones. The direct coupling onto the 2,2-disubstituted cyclopentene-1,3-dione core provides a novel expedient way of enantioselectively desymmetrising all ...
Beattie, N. A. +4 more
core +1 more source
Angewandte Chemie, EarlyView.Covalently linked carbazole dimers exhibit intense excimer‐based circularly polarized luminescence (CPL). A simple propylene‐tethered dimer achieves glum ≈ 0.01 in the violet region—among the highest for small organic emitters without heavy atoms. Conformational mapping reveals CPL is governed by thermodynamic/kinetic control of emissive conformers ...
Tomohiro Kujime, Zhe Wang, Tadashi Mori
wiley +2 more sources
Stereodivergent, Diels-Alder-initiated organocascades employing α,β-unsaturated acylammonium salts: scope, mechanism, and application. [PDF]
, 2017 Chiral α,β-unsaturated acylammonium salts are novel dienophiles enabling enantioselective Diels-Alder-lactonization (DAL) organocascades leading to cis- and trans-fused, bicyclic γ- and δ-lactones from readily prepared dienes, commodity acid chlorides ...
Abbasov, Mikail E +3 more
core +2 more sources
Enantioselective Synthesis of α‐Aminopropargylphosphonates. [PDF]
ChemInform, 2007 AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Rajasekhar, Dodda, Cong-Gui, Zhao
openaire +2 more sources
Angewandte Chemie, EarlyView.The use of transition‐metal catalysts and design of chiral ligands have allowed chemists to access highly functionalized benzofused 5‐ and 6‐ membered rings in high yield and enantioselectivity. A common strategy used relies on an intermolecular carbometalation across alkynes and olefins, usually followed by a subsequent intramolecular carbometalation.
Clara Jans +3 more
wiley +2 more sources
Nature CommunicationsN-bridged [3.2.1]octanes (tropanes) and their related bridged bicyclic systems constitute highly sought-after scaffolds in drug discovery and development.
Chao Fang +5 more
doaj +1 more source
Enanatioselective Switch and Potential Applications in Biocatalysis
CHIMIA, 2023 Enantioselectivity has always been a key feature of enzymatic synthesis. In some cases, when enzymes are not strictly enantioselective, by tuning the reaction conditions it is possible to induce an enantioselective switch.
Lucia Robustini, Francesca Paradisi
doaj +1 more source
Plasmonic Nanomachines: Creating Local Potential Gradients and Motions
Advanced Materials, EarlyView.Plasmonic nanomachines can generate optical, thermal, and chemical potential gradients to drive directional rectilinear, rotational, and twisting motions at the nanometer scale. The integration of multimodal plasmonic forces with functional materials and programmed structural distortions enables precise spatiotemporal actuation, thereby providing a ...
Yoonhee Kim +3 more
wiley +1 more source