Results 61 to 70 of about 2,677,083 (277)
, 2011 Synthesis and enantioselective hydrogenation of seven-membered cyclic imines: substituted dibenzo[b,f][1,4]oxazepinesHighly enantioselective hydrogenation of seven-membered cyclic imines, substituted dibenzo[b,f][1,4]oxazepines, was achieved, with up to ...
Li, Wei +6 more
core +1 more source
NiH‐Catalyzed Enantio‐ and Regioselective Hydroselenylation of Unactivated Alkenes
Advanced Science, EarlyView.Nickel‐hydride‐catalyzed enantio‐ and regioselective hydroselenylation of unactivated alkenes provides access to chiral organoselenium compounds. Enantiodetermining Ni–H insertion followed by single‐electron diselenide activation generates selenyl radical.
Hyung‐Joon Kang +2 more
wiley +1 more source
Electron Donor–Acceptor Complex Catalysis in Synthetic Chemistry
Angewandte Chemie, EarlyView.Electron donor–acceptor (EDA) complexes are moving beyond stoichiometric photoactivation toward catalytic platforms for radical generation. Productive EDA catalysis requires coordinated donor–acceptor association, charge‐transfer excitation, radical reactivity, and vcatalyst turnover.
Tristan von Münchow +3 more
wiley +2 more sources
Catalytic synthesis of chiral sulfinimidate esters via oxidative esterification of sulfenamides
Nature CommunicationsAza-sulfur compounds, such as sulfilimines, sulfoximines, etc, are increasingly recognized as essential contributors to advancements in drug development and asymmetric synthesis.
Hua-Jie Jiang +8 more
doaj +1 more source
Nature Communications, 2021 Chiral acetylenic derivatives are found in many bioactive compounds and are versatile building blocks in organic synthesis. Here, the authors report a mild enantioselective nickel/Lewis acid-catalyzed asymmetric propargylic substitution reaction which is
Xihao Chang +3 more
doaj +1 more source
Green Synthesis and Catalysis, 2021 Chiral α-amino-β2,2-amino acid is an ubiquitous fragment that presents in natural products, pharmaceuticals, and bioactive molecules. However, the catalytic enantioselective synthesis of α-amino-β2,2-amino acids with structural complexity and diversity ...
Xue Tian +4 more
doaj +1 more source
Enantioselective Total Synthesis of (+)‐Tricycloclavulone. [PDF]
ChemInform, 2004 The first total synthesis of (+)-tricycloclavulone having a unique tricyclo[5,3,0,01,4]decane skeleton and six chiral centers was achieved in a highly stereoselective manner. It includes a catalytic enantioselective [2+2]-cycloaddition reaction using novel chiral copper catalyst, extremely effecting an intramolecular ester transfer reaction, and ...
Hisanaka, Ito +4 more
openaire +2 more sources
Highly Enantioselective Synthesis of Sultams via Pd-Catalyzed Hydrogenation
, 2009 Using pd(cf(3)co(2))(2)/(S,S)-f-Binaphane as the catalyst, an efficient enantioselective Synthesis of sultams was developed via asymmetric hydrogenation of the corresponding cyclic imines with high enantioselectivities.
Zhou, Yong-Gui +9 more
core +1 more source
Enantioselective synthesis of hyperparathyroidism agent Cinacalcet hydrochloride [PDF]
, 2022 A simple and efficient route has been developed for enantioselective synthesis of hyperparathyroidism agent (R)-Cinacalcet. The synthesis started from commercially available triflouromethyl benzaldehyde and 1-(naphthalen-1-yl) ethanone and completed in 8
Spandana, K V L D ; Organic Synthesis Laboratory, Fluoro-Agrochemicals Department, CSIR-Indian Institute of Chemical Technology, Hyderabad 500 007, India +2 more
core +1 more source
Enantioselective Access to Trifluoromethylated Spirocyclopropyl Heterocycles
Advanced Science, EarlyView.We report a rhodium‐catalyzed asymmetric [2+1] spirocyclopropanation of methylene azacycles with trifluoromethyl carbenes in situ derived from fluoroalkyl triftosylhydrazones. ABSTRACT Chiral spirocyclopropyl heterocycles have emerged as privileged three‐dimensional structural motifs in medicinal chemistry.
Yuanhao Zhu +9 more
wiley +1 more source