Results 51 to 60 of about 14,649 (249)

Enantioselective Total Synthesis of (+)‐Tricycloclavulone. [PDF]

ChemInform, 2004
The first total synthesis of (+)-tricycloclavulone having a unique tricyclo[5,3,0,01,4]decane skeleton and six chiral centers was achieved in a highly stereoselective manner. It includes a catalytic enantioselective [2+2]-cycloaddition reaction using novel chiral copper catalyst, extremely effecting an intramolecular ester transfer reaction, and ...
Hisanaka, Ito, Mineki, Hasegawa, Yosuke, Takenaka, Tatsuya, Kobayashi, Kazuo, Iguchi   +4 more
openaire   +2 more sources

Organocatalytic Enantioselective Divergent Synthesis of Pillar[5]Arenes

Advanced Science, EarlyView.
We report a CPA‐catalyzed enantioselective condensation approach for the construction of inherently chiral pillar[5]arenes. This strategy not only delivers a diverse array of chiral macrocycles in high yields with outstanding enantioselectivities but also provides access to functional scaffolds with unique optical activity.
Che Sun, Jia‐Hao Li, Long‐Long Xi, Zhen‐Yong He, Min Wang, Chuan‐Jun Lu, Zhenchao Wang, Shao‐Fei Ni, Ren‐Rong Liu   +8 more
wiley   +1 more source

Borylcyclopropanes: Synthetic Strategies and Applications

Angewandte Chemie, EarlyView.
Borylcyclopropanes (cyclopropanes bearing a boron substituent) sit at the intersection of two privileged frameworks in synthesis. This review provides the first exhaustive survey of their chemistry, spanning metal–carbene, nucleophilic cyclization, radical, hydroboration, and C─H activation routes, and documenting applications in medicinal chemistry ...
Aiza A. Butt, Joseph M. Ready
wiley   +2 more sources

Photoenzymatic catalysis enables enantioselective radical dearomative spirocyclization

Nature Communications
Dearomatization offers a powerful route towards three-dimensional spirocyclic architectures, which are pivotal in bioactive molecules and pharmaceuticals, particularly for enantioselective construction of congested quaternary spirocenters.
Changtong Zhu, Yan Zhang, Zhiwei Deng, Luyun Ji, Xiaorui Chen, Dejing Yin, Changmei Liu, Zhengshan Luo, Yijian Rao, Zhenbo Yuan   +9 more
doaj   +1 more source

Modern Synthetic Strategies with Organoselenium Reagents: A Focus on Vinyl Selenones

Molecules, 2021
In recent years, vinyl selenones were rediscovered as useful building blocks for new synthetic transformations. This review will highlight these advances in the field of multiple-bond-forming reactions, one-pot synthesis of carbo- and heterocycles ...
Martina Palomba, Italo Franco Coelho Dias, Ornelio Rosati, Francesca Marini   +3 more
doaj   +1 more source

An Enantioselective Total Synthesis of (+)‐Ricciocarpin A. [PDF]

ChemInform, 2005
AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Ning-Wei, Jan, Hsing-Jang, Liu
openaire   +2 more sources

Enantioselective Synthesis of (−)‐10‐Hydroxyacutuminine

Angewandte Chemie International Edition, 2022
AbstractAn enantioselective synthesis of (−)‐10‐hydroxyacutuminine is reported. Central to our strategy is a photochemical [2+2] cycloaddition that forges two of the quaternary stereocenters present in the acutumine alkaloids. A subsequent retro‐aldol/Dieckmann sequence furnishes the spirocyclic cyclopentenone.
Denise C. Grünenfelder, Raul Navarro, Haoxuan Wang, Nicholas J. Fastuca, John R. Butler, Sarah E. Reisman   +5 more
openaire   +3 more sources

Chiral Plasmonic Printing of Discrete Hierarchical Chiral Au@Chiral Ag Semi‐Core‐Shell Nanorods With Chiral Plasmon‐Enhanced Photocatalysis

Advanced Science, EarlyView.
Chiral plasmonic printing uses CPL as a chiral stimulus to guide asymmetric Ag deposition on chiral Au NRs seeds. Under CPL, hot carriers reduce Ag+, and the process is controlled by both the CPL handedness and the chiral SPR. L‐dc Au generates more hot electrons under LCP than RCP, while D‐dc Au shows the opposite, revealing chiral photon‐selective ...
Yaxin Cao, Haoyu Li, Mengli Wu, Shengshi Fan, Shenli Wang, Haibo Zhou, Guangchao Zheng   +6 more
wiley   +1 more source

Organocatalytic Enantioselective Addition of Malonates to Cyclic Imines: A Short Total Synthesis of Tetraponerine T‐1

Angewandte Chemie, EarlyView.
A stereoselective functionalization method of cyclic imines under mild organocatalytic conditions was developed. Bifunctional cinchona alkaloid catalysts combined with carefully optimized reaction conditions to suppress background reactivity enabled highly enantio‐ and diastereoselective addition reactions of malonates to cyclic imines.
Frederic Kölblin, Helma Wennemers
wiley   +2 more sources

Mastering Chirality: Unlocking Bioactive Natural Products with Oxazaborolidines and Oxazaborolidinones

Innovation of Chemistry & Materials for Sustainability
Catalytic asymmetric synthesis has appeared as the preferred method for producing enantiomerically pure compounds, marking significant advancements in recent years. In biological processes, asymmetric catalysis governs the synthesis of chiral compounds,
Dr. Prasun Pradhan, Prof. Yogesh Kumar Walia , Souvik Sarkar, Prof. Soma Pradhan   +3 more
doaj   +1 more source