Results 71 to 80 of about 14,649 (249)
Thioketone-directed rhodium(I) catalyzed enantioselective C-H bond arylation of ferrocenes
Nature Communications, 2019 The development of straightforward methods for the synthesis of planar chiral ferrocenes remains highly challenging. Here, the authors report a rhodium(I)/phosphonate-catalyzed thioketone-directed enantioselective C-H bond arylation reaction for the ...
Zhong-Jian Cai +4 more
doaj +1 more source
Catalytic enantioselective construction of axial chirality in 1,3-disubstituted allenes
Nature Communications, 2019 Highly enantioselective synthesis of allenes has been relying, so far, on the steric hindrance of substrates. Here the authors achieve excellent stereocontrol in the synthesis of chiral allenes with a palladium-DTBM-SEGPHOS catalytic system in a non ...
Shihua Song +3 more
doaj +1 more source
Angewandte Chemie International Edition, EarlyView.The first catalytic asymmetric formal [3+2] cycloaddition of allylsilanes delivers cis‐2,5‐disubstituted tetrahydrofuran‐3‐ones that serve as versatile intermediates for the synthesis of diverse bioactive scaffolds. ABSTRACT A formal [3+2] cycloaddition via cyclization/1,2‐hydride shift initiated by nucleophilic attack of allylsilanes has been ...
Hosung Lee +5 more
wiley +1 more source
Algicidal lactones from the marine Roseobacter clade bacterium Ruegeria pomeroyi
Beilstein Journal of Organic Chemistry, 2012 Volatiles released by the marine Roseobacter clade bacterium Rugeria pomeroyi were collected by use of a closed-loop stripping headspace apparatus (CLSA) and analysed by GC–MS.
Ramona Riclea +5 more
doaj +1 more source
Enantioselective Total Synthesis of (−)‐Blennolide A
Chemistry – A European Journal, 2013 AbstractBlennolide A can be synthesized through an enantioselective domino‐Wacker/carbonylation/methoxylation reaction of 7 a with 96 % ee and an enantioselective Wacker oxidation of 7 b with 89 % ee. Further transformations led to the α,β‐unsaturated ester (E)‐17, which was subjected to a highly selective Michael addition, introducing a methyl group ...
Tietze, Lutz Friedjan +4 more
openaire +3 more sources
Total synthesis of 4-((3S,5R)-3,5- dihydroxynonadecyl)phenol
Results in ChemistryThis communication describes a short and effective synthetic route for the enantioselective synthesis of 4-((3S,5R)-3,5-dihydroxynonadecyl)phenol. Key steps in this synthesis include the Wittig reaction, Barbier allylation, and Sharpless dihydroxylation.
Krishnaiah Kumari +5 more
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Beilstein Journal of Organic Chemistry, 2014 Pd-catalyzed enantioselective alkylation in conjunction with further synthetic elaboration enables the formal total syntheses of a number of “classic” natural product target molecules. This publication highlights recent methods for setting quaternary and
Yiyang Liu +11 more
doaj +1 more source
Angewandte Chemie International Edition, EarlyView.A highly versatile and general strategy is presented for the scalable production of practical quantities of ω‐substituted α‐olefins using tris(ω‐substituted alkyl)aluminum telogens that are readily available through a “green” synthesis from commodity triisobutylaluminum and ethene as the taxogen. These new α‐olefins can be designed and used as monomers
Lauren G. Logue +4 more
wiley +1 more source
Advanced ScienceHere, a photocatalytic asymmetric multicomponent cascade Minisci reaction of β‐carbolines with enamides and diazo compounds is reported, enabling an effective enantioselective radical C─H functionalization of β‐carbolines with high yields and ...
Yi‐Jie Gu +4 more
doaj +1 more source
Nature CommunicationsThe field of nickel catalysis has witnessed remarkable growth in recent years. However, the use of nickel catalysts in enantioselective C–H activation remains a daunting challenge because of their variable oxidation states, intricate coordination ...
Qi-Jun Yao +3 more
doaj +1 more source