[2,2′-Bipyridin]-6(1H)-one, a Truly Cooperating Ligand in the Palladium-Mediated C–H Activation Step: Experimental Evidence in the Direct C-3 Arylation of Pyridine [PDF]
, 2018 Producción CientíficaThe ligand [2,2′-bipyridin]-6(1H)-one (bipy-6-OH) has a strong accelerating effect on the Pd- catalyzed direct arylation of pyridine or arenes.
Albéniz Jiménez, Ana Carmen +2 more
core +4 more sources
Enantioselective Total Synthesis of Aplyviolene [PDF]
Journal of the American Chemical Society, 2011 The enantioselective total synthesis of the rearranged spongian diterpene aplyviolene has been completed in 14 steps from the known hydroazulenone 8. The key junction of the hydrocarbon and oxygenated fragments to form the critical C8 quaternary carbon stereocenter and set the stage for elaborating the delicate bicyclic lactone functionality was ...
Martin J, Schnermann, Larry E, Overman
openaire +2 more sources
Molybdenum-catalyzed enantioselective sulfoxidation controlled by a nonclassical hydrogen bond between coordinated chiral imidazolium-based dicarboxylate and peroxido ligands [PDF]
, 2018 Chiral alkyl aryl sulfoxides were obtained by molybdenum-catalyzed oxidation of alkyl aryl sulfides with hydrogen peroxide as oxidant in mild conditions with high yields and moderate enantioselectivities.
Carrasco Carrasco, Carlos Jesús +2 more
core
Enantioselective Total Synthesis of (+)-Salvileucalin B [PDF]
, 2011 An enantioselective total synthesis of the diterpenoid natural product (+)-salvileucalin B is reported. Key findings include a copper-catalyzed arene cyclopropanation reaction to provide the unusual norcaradiene core and a reversible retro ...
Levin, Sergiy +2 more
core +1 more source
The supramolecular attitude of metal-salophen and metal-salen complexes [PDF]
, 2018 In this review we cover some aspects of metal-salophen and metal-salen complex chemistry related to their supramolecular attitude. We examined under the lens of the non-covalent interactions their potential to behave as building blocks for auto-assembled
Dalla Cort, Antonella, Leoni, Luca
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Enantioselective Synthesis of Endohedral Metallofullerenes
Journal of the American Chemical Society, 2011 Endohedral metallofullerenes are promising materials in biomedical and material sciences. In particular, they are of interest as agents for magnetic resonance imaging (MRI), photovoltaic devices, and semimetallic components. The synthesis of chiral endofullerenes represents one step further in the potential use of these carbon allotropes; however, this
Sawai K. +10 more
openaire +3 more sources
Photochemical Approaches to Complex Chemotypes: Applications in Natural Product Synthesis. [PDF]
, 2016 The use of photochemical transformations is a powerful strategy that allows for the formation of a high degree of molecular complexity from relatively simple building blocks in a single step. A central feature of all light-promoted transformations is the
Kärkäs, Markus D. +2 more
core +2 more sources
Enantioselective Total Synthesis of (+)-Amabiline [PDF]
Organic Letters, 2012 The first total synthesis of (+)-amabiline, an unsaturated pyrrolizidine alkaloid from Cynoglossum amabile, is reported. This convergent, enantioselective synthesis proceeds in 15 steps (10-step longest linear sequence) in 6.2% overall yield and features novel methodology to construct the unsaturated pyrrolizidine or (-)-supinidine core.
Timothy J, Senter +2 more
openaire +2 more sources
Focus on chirality of HIV-1 non-nucleoside reverse transcriptase inhibitors [PDF]
, 2016 Chiral HIV-1 non-nucleoside reverse transcriptase inhibitors (NNRTIs) are of great interest since one enantiomer is often more potent than the corresponding counterpart against the HIV-1 wild type (WT) and the HIV-1 drug resistant mutant strains.
Famiglini, Valeria, Silvestri, Romano
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Thioketone-directed rhodium(I) catalyzed enantioselective C-H bond arylation of ferrocenes
Nature Communications, 2019 The development of straightforward methods for the synthesis of planar chiral ferrocenes remains highly challenging. Here, the authors report a rhodium(I)/phosphonate-catalyzed thioketone-directed enantioselective C-H bond arylation reaction for the ...
Zhong-Jian Cai +4 more
doaj +1 more source