Results 1 to 10 of about 12,531 (256)

Enantioselective protonation [PDF]

Nature Chemistry, 2009
Enantioselective protonation is a common process in biosynthetic sequences. The decarboxylase and esterase enzymes that effect this valuable transformation are able to control both the steric environment around the proton acceptor (typically an enolate) and the proton donor (typically a thiol).
Mohr, Justin T., Hong, Allen Y., Stoltz, Brian M.   +2 more
openaire   +4 more sources

Supramolecular Chiral Nanozymes with High and Switchable Enantioselectivity

Small Structures, 2023
Understanding and manipulation of catalytic enantioselectivity have emerged as a paramount challenge for decades. Inspired by nature, nanozymes with enantioselectivity have been designed.
Chu Wang, Ganyin Yuan, Chao Wang, Xiaohuan Sun, Pengyuan Hang, Zheng Xi, Jie Han, Rong Guo   +7 more
doaj   +1 more source

Enantioselective Synthesis of N1999A2. [PDF]

ChemInform, 2006
AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Nan, Ji, Hardwin, O'Dowd, Brad M, Rosen, Andrew G, Myers   +3 more
openaire   +3 more sources

The Enantioselective Tsuji Allylation [PDF]

Journal of the American Chemical Society, 2004
The first catalytic enantioselective examples of the Tsuji allylation using enol carbonates and enol silanes are described. The products possess a quaternary stereogenic center and are useful building blocks for synthetic chemistry.
Behenna, Douglas C., Stoltz, Brian M.
openaire   +3 more sources

Biomolecular Chemical Simulations on Enantioselectivity and Reactivity of Lipase Enzymes to Azulene Derivatives

Natural Product Communications, 2022
Biomolecular chemical simulations have recently become a useful research method in the fields of organic chemistry and bioscience. In the last few years, we have been focusing on the biomolecular computational simulation on lipase enzyme and ligand ...
Yoichiro Yagi, Takatomo Kimura, Makoto Kamezawa   +2 more
doaj   +1 more source

Comprehensive Analysis of a Yeast Lipase Family in the Yarrowia Clade. [PDF]

PLoS ONE, 2015
Lipases are currently the subject of intensive studies due to their large range of industrial applications. The Lip2p lipase from the yeast Yarrowia lipolytica (YlLIP2) was recently shown to be a good candidate for different biotechnological applications.
Muchalin Meunchan, Stéphanie Michely, Hugo Devillers, Jean-Marc Nicaud, Alain Marty, Cécile Neuvéglise   +5 more
doaj   +1 more source

Directed evolution of lipase A from Bacillus subtilis for the preparation of enantiocomplementary sec-alcohols

Green Synthesis and Catalysis, 2021
Biocatalysts with tailor-made or controllable stereoselectivity are valuable and highly desired in the precision synthesis of chiral compounds. Most lipases display excellent (R)-enantioselectivity for various sec-alcohols.
Danyang Li, Xiaoyang Chen, Zhichun Chen, Xianfu Lin, Jian Xu, Qi Wu   +5 more
doaj   +1 more source

Computational Study of Mechanism and Enantioselectivity of Imine Reductase from Amycolatopsis orientalis

ChemistryOpen, 2022
Imine reductases (IREDs) are NADPH‐dependent enzymes (NADPH=nicotinamide adenine dinucleotide phosphate) that catalyze the reduction of imines to amines.
Dr. Mario Prejanò, Prof. Dr. Xiang Sheng, Prof. Dr. Fahmi Himo   +2 more
doaj   +1 more source

Enantioselectivity of discretized helical supramolecule consisting of achiral cobalt phthalocyanines via chiral-induced spin selectivity effect

Nature Communications, 2023
Enantioselectivity of helical aggregation is conventionally directed either by its homochiral ingredients or by introduction of chiral catalysis. The fundamental question, then, is whether helical aggregation that consists only of achiral components can ...
Hiroki Aizawa, Takuro Sato, Saori Maki-Yonekura, Koji Yonekura, Kiyofumi Takaba, Tasuku Hamaguchi, Taketoshi Minato, Hiroshi M. Yamamoto   +7 more
doaj   +1 more source

Engineering of Yeast Old Yellow Enzyme OYE3 Enables Its Capability Discriminating of (E)-Citral and (Z)-Citral

Molecules, 2021
The importance of yeast old yellow enzymes is increasingly recognized for direct asymmetric reduction of (E/Z)-citral to (R)-citronellal. As one of the most performing old yellow enzymes, the enzyme OYE3 from Saccharomyces cerevisiae S288C exhibited ...
Tairan Wang, Ran Wei, Yingting Feng, Lijun Jin, Yunpeng Jia, Duxia Yang, Zuonan Liang, Mengge Han, Xia Li, Chenze Lu, Xiangxian Ying   +10 more
doaj   +1 more source