Results 41 to 50 of about 32,089 (279)

Evolving P450pyr Monooxygenase for Regio- and Stereoselective Hydroxylations

CHIMIA, 2015
P450pyr monooxygenase from Sphingomonas sp. HXN-200 catalysed the regio- and stereoselective hydroxylation at a non-activated carbon atom, a useful but challenging reaction in classic chemistry, with unique substrate specificity for a number of ...
Yi Yang, Zhi Li
doaj   +1 more source

Prediction of Enantioselectivity in Rhodium Catalyzed Hydrogenations

, 2009
Prediction of Enantioselectivity in Rhodium Catalyzed ...
Patrick J. Donoghue (2149213), Paul Helquist (301513), Per-Ola Norrby (1306665), Olaf Wiest (105849), Norrby, Per-Ola,, Helquist, Paul, Wiest, Olaf, Donoghue, Patrick J   +7 more
core   +1 more source

Chiral separation of chloroalkanes with the chromatographic column onboard Martian rovers

FEBS Letters, EarlyView.
Computer image of the Rosalind Franklin Rover of ESA's ExoMars mission. ExoMars is scheduled to land on planet Mars in Oxia Planum in 2029. This area represents an interesting spot to look for biosignatures. Investigations of ExoMars include measurement on molecular chirality. We show that chiral chloroalkanes, that have been identified on Mars, can be
Asma Merzougui, Agnes Banreti, Armelle L. Ernst, Guillaume Leseigneur, Uwe J. Meierhenrich   +4 more
wiley   +1 more source

Enhanced stereodivergent evolution of carboxylesterase for efficient kinetic resolution of near-symmetric esters through machine learning

Nature Communications
Carboxylesterases serve as potent biocatalysts in the enantioselective synthesis of chiral carboxylic acids and esters. However, naturally occurring carboxylesterases exhibit limited enantioselectivity, particularly toward ethyl 3-cyclohexene-1 ...
Zhe Dou, Xuanzao Chen, Ledong Zhu, Xiangyu Zheng, Xiaoyu Chen, Jiayu Xue, Satomi Niwayama, Ye Ni, Guochao Xu   +8 more
doaj   +1 more source

Efficient Improving the Activity and Enantioselectivity of Candida rugosa Lipase for the Resolution of Naproxen by Enzyme Immobilization on MCM-41 Mesoporous Molecular Sieve [PDF]

International Journal Bioautomation, 2015
Lipase from Candida rogusa was immobilized on MCM-41 mesoporous molecular sieves in a trapped aqueous-organic biphase system for the resolution of racemic naproxen methyl ester.
Ying Chen, Yi Xu, Xiao-mei Wu
doaj  

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Stereoselective bioaccumulation and degradation of chiral pesticide hexythiazox in earthworm-soil microcosm

Ecotoxicology and Environmental Safety
The chiral pesticide hexythiazox was extensively employed in agricultural activities and has garnered growing concern for its harmful impact on the ecosystem.
Ningying Song, Jiyang Zhuang, Hu Zhang, Mingrong Qian, Huizhen Wu, Nabo Sun   +5 more
doaj   +1 more source

Bioresolution Production of (2R,3S)-Ethyl-3-phenylglycidate for Chemoenzymatic Synthesis of the Taxol C-13 Side Chain by Galactomyces geotrichum ZJUTZQ200, a New Epoxide-Hydrolase-Producing Strain

Molecules, 2014
A newly isolated Galactomyces geotrichum ZJUTZQ200 strain containing an epoxide hydrolase was used to resolve racemic ethyl 3-phenylglycidate (rac-EPG) for producing (2R,3S)-ethyl-3-phenylglycidate ((2R,3S)-EPG). G.
Chun Wei, Jinlong Ling, Honglei Shen, Qing Zhu   +3 more
doaj   +1 more source

A Chiral Metal—Organic Framework Prepared on Large-Scale for Sensitive and Enantioselective Fluorescence Recognition

Molecules, 2023
MOF-based luminescent sensors have garnered considerable attention due to their potential in recognition and discrimination with high sensitivity, selectivity, and fast response in the last decades.
Xin-Mei Zhang, Yan-Mei Bai, Lu-Lu Ai, Fang-Hui Wu, Wei-Long Shan, Yan-Shang Kang, Li Luo, Kai Chen, Fan Xu   +8 more
doaj   +1 more source

enantioselectivity [PDF]

, 2014
Citation: 'enantioselectivity' in the IUPAC Compendium of Chemical Terminology, 3rd ed.; International Union of Pure and Applied Chemistry; 2006. Online version 3.0.1, 2019. 10.1351/goldbook.E02082 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual terms.
openaire   +1 more source