Results 11 to 20 of about 12,531 (256)

Engineering the Enantioselectivity of Yeast Old Yellow Enzyme OYE2y in Asymmetric Reduction of (E/Z)-Citral to (R)-Citronellal

Molecules, 2019
The members of the Old Yellow Enzyme (OYE) family are capable of catalyzing the asymmetric reduction of (E/Z)-citral to (R)-citronellal—a key intermediate in the synthesis of L-menthol. The applications of OYE-mediated biotransformation are usually
Xiangxian Ying, Shihua Yu, Meijuan Huang, Ran Wei, Shumin Meng, Feng Cheng, Meilan Yu, Meirong Ying, Man Zhao, Zhao Wang   +9 more
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Redesign of a short-chain dehydrogenase/reductase for asymmetric synthesis of ethyl (R)-2-hydroxy-4-phenylbutanoate based on per-residue free energy decomposition and sequence conservatism analysis

Green Synthesis and Catalysis, 2020
As an important building block for the synthesis of angiotensin-converting enzyme inhibitors, ethyl (R)-2-hydroxyl-4-phenylbutanoate [(R)-HPBE] has attracted increasing attention.
Bingmei Su, Lian Xu, Xinqi Xu, Lichao Wang, Aipeng Li, Juan Lin, Lidan Ye, Hongwei Yu   +7 more
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Enantioselective Synthesis of (+)‐Majusculone (I). [PDF]

ChemInform, 2007
AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Douglass F, Taber, M Inthikhab, Sikkander, Pierre H, Storck   +2 more
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Enantioselectivity-Evaluation of Chiral Copper(II) Complexes Coordinated by Novel Chiral Tetradentate Ligands for Free Amino Acids by Mass Spectrometry Coupled With the Isotopically Labeled Enantiomer Method

Frontiers in Chemistry, 2020
A series of copper(II) complexes with chiral tetradentate ligands, N,N′-ethylene- bis(S-amino acid methyl amide or methyl ester) prepared from S-alanine, S-phenylalanine, S-valine or S-proline, was generated in methanol.
Takashi Nakakoji, Kaori Yoshino, Kazuki Izutsu, Hirofumi Sato, Hiroyuki Miyake, Eiko Mieda, Satoshi Shinoda, Hiroshi Tsukube, Hideya Kawasaki, Ryuichi Arakawa, Daisuke Ono, Motohiro Shizuma   +11 more
doaj   +1 more source

Flexible Enantioselectivity of Tryptophanase Attributable to Benzene Ring in Heterocyclic Moiety of D-Tryptophan

Life, 2012
The invariance principle of enzyme enantioselectivity must be absolute because it is absolutely essential to the homochiral biological world. Most enzymes are strictly enantioselective, and tryptophanase is one of the enzymes with extreme absolute ...
Akihiko Shimada, Haruka Ozaki
doaj   +1 more source

Enantioselective Synthesis of 2,2-Disubstituted Terminal Epoxides via Catalytic Asymmetric Corey-Chaykovsky Epoxidation of Ketones

Molecules, 2012
Catalytic asymmetric Corey-Chaykovsky epoxidation of various ketones with dimethyloxosulfonium methylide using a heterobimetallic La-Li3-BINOL complex (LLB) is described.
Shigeki Matsunaga, Masakatsu Shibasaki, Toshihiko Sone, Akitake Yamaguchi   +3 more
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From Mechanistic Study to Chiral Catalyst Optimization: Theoretical Insight into Binaphthophosphepine-catalyzed Asymmetric Intramolecular [3 + 2] Cycloaddition

Scientific Reports, 2017
Density functional M11 was used to study the mechanism and enantioselectivity of a binaphthophosphepine-catalyzed intramolecular [3 + 2] cycloaddition reaction.
Meng Duan, Lei Zhu, Xiaotian Qi, Zhaoyuan Yu, Yingzi Li, Ruopeng Bai, Yu Lan   +6 more
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Homochiral Metal-Organic Framework Based Mixed Matrix Membrane for Chiral Resolution

Membranes, 2022
Efficient separation of enantiomers is critical in the chemical, pharmaceutical, and food industries. However, conventional separation methods, such as chromatography, crystallization, and enzymatic kinetic resolution, require high energy costs and ...
Hwa-Jin Choi, Dong-Yeun Koh
doaj   +1 more source

Organocatalyzed Enantioselective Fluorocyclizations

Angewandte Chemie International Edition, 2011
Enantioenriched fluorinated heterocycles can be prepared through fluorocyclizations of prochiral indoles (see scheme; Ts=tosyl, Bn=benzyl, Boc=tert-butoxycarbonyl). More than twenty examples for this cascade fluorination-cyclization, which is catalyzed by cinchona alkaloids and employs N-fluorobenzenesulfonimide as the electrophilic fluorine source ...
Lozano, O, Blessley, G, Martinez del Campo, T, Thompson, A, Giuffredi, G, Bettati, M, Walker, M, Borman, R, Gouverneur, V   +8 more
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Synthetic Cathinones: Recent Developments, Enantioselectivity Studies and Enantioseparation Methods

Molecules, 2022
New psychoactive substances represent a public health threat since they are not controlled by international conventions, are easily accessible online and are sold as a legal alternative to illicit drugs. Among them, synthetic cathinones are widely abused
Ana Sofia Almeida, Bárbara Silva, Paula Guedes de Pinho, Fernando Remião, Carla Fernandes   +4 more
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