Results 21 to 30 of about 3,258 (176)

Recent Developments and Trends in Asymmetric Organocatalysis. [PDF]

open access: yesEuropean J Org Chem, 2023
AbstractAsymmetric organocatalysis has experienced a long and spectacular way since the early reports over a century ago by von Liebig, Knoevenagel and Bredig, showing that small (chiral) organic molecules can catalyze (asymmetric) reactions. This was followed by impressive first highly enantioselective reports in the second half of the last century ...
García Mancheño O, Waser M.
europepmc   +4 more sources

Cross-trienamines in asymmetric organocatalysis. [PDF]

open access: yesJ Am Chem Soc, 2012
Cross-conjugated trienamines are introduced as a new concept in asymmetric organocatalysis. These intermediates are applied in highly enantioselective Diels-Alder and addition reactions, providing functionalized bicyclo[2.2.2]octane compounds and γ'-addition products, respectively.
Halskov KS   +5 more
europepmc   +3 more sources

Recent Advances in the Enantioselective Radical Reactions

open access: yesMolecules, 2023
The review covers research published since 2017 and is focused on enantioselective synthesis using radical reactions. It describes recent approaches to the asymmetric synthesis of chiral molecules based on the application of the metal catalysis, dual ...
Tomasz Bauer   +2 more
doaj   +1 more source

Asymmetric Organocatalysis with Chiral Covalent Organic Frameworks

open access: yesOrganic Materials, 2021
Inspired by Mother Nature, the use of chiral covalent organic frameworks as heterogeneous asymmetric organocatalysts has arisen over the last decade as a new method in enantioselective synthesis.
Song-Chen Yu, Liang Cheng, Li Liu
doaj   +1 more source

Asymmetric organocatalysis involving double activation

open access: yesTetrahedron Chem, 2022
Asymmetric organocatalysis contributed tremendously to the field of organic synthesis since year 2000. Considering the diversity of organocatalysts and their activation modes, chemists developed the double activation strategy, in which two distinct ...
Zhi Chen   +3 more
doaj   +1 more source

Recent Advances in Asymmetric Synthesis of Pyrrolidine-Based Organocatalysts and Their Application: A 15-Year Update

open access: yesMolecules, 2023
In 1971, chemists from Hoffmann-La Roche and Schering AG independently discovered a new asymmetric intramolecular aldol reaction catalyzed by the natural amino acid proline, a transformation now known as the Hajos–Parrish–Eder–Sauer–Wiechert reaction ...
Arianna Quintavalla   +2 more
doaj   +1 more source

Synergistic Organo‐Organocatalysis [PDF]

open access: yes, 2023
Asymmetric organocatalysis is pivotal in the field of asymmetric catalysis and is a crucial technology platform in the industry. However, in some cases, catalysis may have reached its limit and synergistic catalysis is an interesting groundbreaking ...
Pesciaioli, Fabio   +3 more
core   +1 more source

Organocatalysts for enantioselective synthesis of fine chemicals: definitions, trends and developments

open access: yesScienceOpen Research, 2015
Organocatalysis, that is the use of small organic molecules to catalyse organic transformations, has been included among the most successful concepts in asymmetric catalysis and it has been used for the enantioselective construction of C-C, C-N, C-O, C-S,
Chiara Palumbo
doaj   +5 more sources

Asymmetric organocatalysis at the service of medicinal chemistry. [PDF]

open access: yesISRN Org Chem, 2014
The application of the most representative and up-to-date examples of homogeneous asymmetric organocatalysis to the synthesis of molecules of interest in medicinal chemistry is reported. The use of different types of organocatalysts operative via noncovalent and covalent interactions is critically reviewed and the possibility of running some of these ...
Ricci A.
europepmc   +4 more sources

Why are Aromatic Additives Effective in Asymmetric Organocatalysis? [PDF]

open access: yes, 2022
The presence of an aromatic additive has been seen to enhance, often significantly, the yield and enantioselectivityof the desired product in asymmetric organocatalysis.Considering their success across a dizzying range of organocatalysts and organic ...
Kumar, Vanka, Subhrashis, Banerjee
core   +1 more source

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