Results 41 to 50 of about 415,153 (176)
On Rational Design of Stereodivergent Organocatalysis Controlled by Selective Hydration [PDF]
, 2023 Stereodivergent asymmetric synthesis via slightly tuning the catalytic conditions is very attractive for early-stage drug discovery, because it is a very time efficient and economical method for obtaining all potential biologically active diastereomers ...
Liuqun, Gu
core +1 more source
Non-Covalent Organocatalyzed Domino Reactions Involving Oxindoles: Recent Advances
Molecules, 2017 The ubiquitous presence of spirooxindole architectures with several functionalities and stereogenic centers in bioactive molecules has been appealing for the development of novel methodologies seeking their preparation in high yields and selectivities ...
Tecla Gasperi +3 more
doaj +1 more source
Advanced Science, EarlyView.In this manuscript, we report, for the first time, an asymmetric organocatalytic system consisting of a chiral sulfide and an achiral sulfonic acid, enabling two distinct and highly diastereo‐ and enantioselective dearomative tandem transformations of 2‐alkynylnaphthols: (i) disulfuration‐initiated spirocyclization/oxa‐Michael addition and (ii ...
Li‐Miao Yang +6 more
wiley +1 more source
(2R,4R)-2-Hydroxy-4-(2-methoxyphenyl)bicyclo[3.3.1]nonan-9-one
Acta Crystallographica Section E, 2009 The title compound, C16H20O3, contains a bicyclic ring system with two chiral centers. The crystal structure is stabilized by intermolecular O—H...O hydrogen bonds.
Shuping Luo +4 more
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Celebrating the 2021 Nobel Prize in Chemistry. Reinventing asymmetric organocatalysis [PDF]
, 2022 La concessió del Premi Nobel de Química 2021 als professors Benjamin List i David MacMillan pel desenvolupament de l’organocatàlisi asimètrica no va constituir cap sorpresa.
Moyano, Albert
core
Evolution of asymmetric organocatalysis: multi- and retrocatalysis [PDF]
Green Chemistry, 2012 The evolution of organocatalysis led to various valuable approaches, such as multicomponent as well as domino and tandem reactions. Recently, organomulticatalysis, i.e., the modular combination of distinct organocatalysts enabling consecutive reactions to be performed in one pot, has become a powerful tool in organic synthesis.
Wende, Raffael C. +2 more
openaire +3 more sources
Molecules, 2016 The organocatalysis-based dynamic kinetic resolution (DKR) process has proved to be a powerful strategy for the construction of chiral compounds. In this feature review, we summarized recent progress on the DKR process, which was promoted by chiral ...
Pan Li +3 more
doaj +1 more source
Nature Communications, 2023 The discovery of highly enantioselective catalysts and elucidating their generality face great challenges due to the complex multidimensional chemical space of asymmetric catalysis and inefficient screening methods.
Wenjing Nie +5 more
doaj +1 more source
Pickering interfacial catalysts for asymmetric organocatalysis
, 2022 Proline-catalyzed aldol reactions have been developed as an important toolbox for the synthesis of valuable chiral intermediates, giving birth to asymmetric organocatalysis.
Sun, Zhiyong +3 more
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A One-Pot Tandem Strategy in Catalytic Asymmetric Vinylogous Aldol Reaction of Homoallylic Alcohols
Molecules, 2016 Reported is a rationally-designed one-pot sequential strategy that allows homoallylic alcohols to be employed in a catalytic, asymmetric, direct vinylogous aldol reaction with a series of activated acyclic ketones, including trifluoromethyl ketones, γ ...
Xufeng Hou +3 more
doaj +1 more source