Design, synthesis, and evaluation of chiral thiophosphorus acids as organocatalysts
Beilstein Journal of Organic Chemistry, 2022 A series of P-stereogenic chiral phosphorus acids (CPAs) were synthesized to determine the requirements for efficient asymmetric organocatalysis. In order to eliminate the need for C2-symmetry in common CPAs, various scaffolds containing C1-symmetrical ...
Karen R. Winters, Jean-Luc Montchamp
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Recent Advances in Asymmetric Organocatalyzed Conjugate Additions to Nitroalkenes
Molecules, 2017 The asymmetric conjugate addition of carbon and heteroatom nucleophiles to nitroalkenes is a very interesting tool for the construction of highly functionalized synthetic building blocks.
Diego A. Alonso +6 more
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Asymmetric catalysis in synthetic strategies for chiral benzothiazepines
Green Synthesis and Catalysis, 2020 Chiral benzothiazepines constitute the core structures of many foremost pharmaceuticals with diverse biological activities endowed by their unique scaffolds, which poses a great challenge to organic chemists and pharmaceutical researchers.
Haifeng Wang +4 more
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Asymmetric reactions of N-heterocyclic carbene (NHC)-based chiral acyl azoliums and azolium enolates
Green Synthesis and Catalysis, 2021 N-Heterocyclic carbene (NHC) organocatalysis has been recognized as a powerful synthetic strategy for the construction of a wide variety of medicinally and biologically important molecules.
Changgui Zhao +2 more
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A Genetic Optimization Strategy with Generality in Asymmetric Organocatalysis as Primary Target [PDF]
, 2023 A catalyst possessing a broad substrate scope, in terms of both turnover and enantioselectivity, is sometimes called “general”. Despite their great utility in asymmetric synthesis, truly general catalysts are difficult or expensive to discover via ...
Alexander, Makaveev +5 more
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On Rational Design of Stereodivergent Organocatalysis Controlled by Selective Hydration [PDF]
, 2023 Stereodivergent asymmetric synthesis via slightly tuning the catalytic conditions is very attractive for early-stage drug discovery, because it is a very time efficient and economical method for obtaining all potential biologically active diastereomers ...
Liuqun, Gu
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Oxadendralenes in asymmetric organocatalysis for the construction of tetrahydroisochromenes. [PDF]
Chem Sci, 2016 Oxadendralenes are integrated in a novel manner into a one-pot cascade utilizing synergistic catalysis for the construction of valuable and complex bicyclic heterocyclic scaffolds.
Hammer N +4 more
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Celebrating the 2021 Nobel Prize in Chemistry. Reinventing asymmetric organocatalysis [PDF]
, 2022 La concessió del Premi Nobel de Química 2021 als professors Benjamin List i David MacMillan pel desenvolupament de l’organocatàlisi asimètrica no va constituir cap sorpresa.
Moyano, Albert
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Non-Covalent Organocatalyzed Domino Reactions Involving Oxindoles: Recent Advances
Molecules, 2017 The ubiquitous presence of spirooxindole architectures with several functionalities and stereogenic centers in bioactive molecules has been appealing for the development of novel methodologies seeking their preparation in high yields and selectivities ...
Tecla Gasperi +3 more
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Halides as versatile anions in asymmetric anion-binding organocatalysis
Beilstein Journal of Organic Chemistry, 2021 This review intends to provide an overview on the role of halide anions in the development of the research area of asymmetric anion-binding organocatalysis.
Lukas Schifferer +3 more
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