Cluster Preface: Non-Covalent Interactions in Asymmetric Catalysis [PDF]
, 2016 The successful harnessing of non-covalent interactions to activate functional groups and control selectivity in chemical reactions is a relatively recent phenomenon in synthetic chemistry, but one that has delivered ground-breaking results, particularly ...
Phipps, RJ
core +2 more sources
Cooperative effects between arginine and glutamic acid in the amino acid catalyzed aldol reaction [PDF]
, 2017 Catalysis of the aldol reaction between cyclohexanone and 4-nitrobenzaldehyde by mixtures of L-Arg and of L-Glu in wet DMSO takes place with higher enantioselectivity (up to a seven-fold enhancement in the anti- aldol for the 1:1 mixture) than that ...
Moyano i Baldoire, Albert +1 more
core +1 more source
Organocatalytic Enantioselective Henry Reactions [PDF]
, 2011 This is an open access article distributed under the Creative Commons Attribution License.A large number of interesting organocatalytic enantioselective protocols have been explored and successfully applied in the last decade.
Herrera, Raquel P. +2 more
core +2 more sources
Solvent-Free Enantioselective Organocatalyzed Aldol Reactions [PDF]
, 2014 The use of proline as catalyst for the aldol process has given a boost to the development of organocatalysis as a research area. Since then, a plethora of organocatalysts of diverse structures have been developed for this and other organic ...
Bañón Caballero, Abraham +2 more
core +2 more sources
Kinetics and mechanism of organocatalytic aza-Michael additions: direct observation of enamine intermediates. [PDF]
, 2012 The imidazoles 1a–g add to the CC-double bond of the iminium ion 2 with rate constants as predicted by the equation log k = sN(N + E). Unfavourable proton shifts from the imidazolium unit to the enamine fragment in the adduct 3 account for the failure of
Ahrendt +33 more
core +1 more source
Palladium and Organocatalysis: An Excellent Recipe for Asymmetric Synthesis
Molecules, 2013 The dual activation of simple substrates by the combination of organocatalysis and palladium catalysis has been successfully applied in a variety of different asymmetric transformations.
Isidro M. Pastor +3 more
doaj +1 more source
Halides as versatile anions in asymmetric anion-binding organocatalysis
Beilstein Journal of Organic Chemistry, 2021 This review intends to provide an overview on the role of halide anions in the development of the research area of asymmetric anion-binding organocatalysis.
Lukas Schifferer +3 more
doaj +1 more source
Reaction Mechanism of Organocatalytic Michael Addition of Nitromethane to Cinnamaldehyde: A Case Study on Catalyst Regeneration and Solvent Effects [PDF]
, 2017 The Michael addition of nitromethane to cinnamaldehyde has been computationally studied in the absence of a catalyst and the presence of a biotinylated secondary amine by a combined computational and experimental approach. The calculations were performed
Luk, Louis Y. P. +4 more
core +4 more sources
Asymmetric Organocatalysis—A Game Changer [PDF]
Chemistry International, 2022 Abstract This year’s Nobel Prize in Chemistry was awarded to Benjamin List and David MacMillan “for the development of asymmetric organocatalysis.” IUPAC congratulates the laureates for their achievements.
openaire +1 more source
Non-Covalent Organocatalyzed Domino Reactions Involving Oxindoles: Recent Advances
Molecules, 2017 The ubiquitous presence of spirooxindole architectures with several functionalities and stereogenic centers in bioactive molecules has been appealing for the development of novel methodologies seeking their preparation in high yields and selectivities ...
Tecla Gasperi +3 more
doaj +1 more source