Results 61 to 70 of about 415,153 (176)
European Journal of Organic Chemistry, EarlyView.Quinine‐catalyzed enantioselective conjugate addition of malononitrile derivatives to enynes provides trisubstituted chiral allenes in good to excellent yields and high enantiopurities under mild conditions. Broad substrate scope, easy scalability, and versatile post‐synthetic transformations into enantioenriched pyrazoles and furans highlight the ...
Martin Kamlar +3 more
wiley +1 more source
Going Full Circle with Organocatalysis and Biocatalysis: The Latent Potential of Cofactor Mimics in Asymmetric Synthesis [PDF]
, 2023 Many enzymes work in tandem with small molecule cofactors, which have inspired organocatalyst designs. Chemical modification of cofactor scaffolds has increased organocatalytic reactivity and reaction scope.
David R. W. Hodgson +5 more
core +1 more source
Catalytic Asymmetric Amino Acid and Its Derivatives by Chiral Aldehyde Catalysis
Frontiers in Chemistry, 2021 Amine acid transformation is an important chemical process in biological systems. As a well-developed and acknowledged tool, chiral aldehyde catalysis provides good catalytic activation and stereoselective control abilities in the asymmetric reaction of ...
Kaijin Lin +4 more
doaj +1 more source
Carbon‐Supported Catalytic Systems Assembled by π–π Interactions
European Journal of Organic Chemistry, EarlyView.This review explores the noncovalent immobilization of organic and organometallic catalysts on carbonaceous supports through π–π interactions, highlighting its potential to enhance catalyst recovery, recyclability, and the sustainability of organic synthesis.
Chloé Jamalkhan +8 more
wiley +1 more source
Asymmetric organocatalysis on a technical scale: current status and future challenges
, 2008 Gröger H. Asymmetric organocatalysis on a technical scale: current status and future challenges. In: Reetz MT, List B, Jaroch S, Weinmann H, Schering Stiftung, eds. Organocatalysis. Ernst Schering Foundation Symposium Proceedings, 2007-2.
Reetz, M.T. +7 more
core +1 more source
Transformative Chemistry, EarlyView.Direct asymmetric α‐C conjugate addition of aminoacetonitrile enabled by carbonyl/iminium double activation, together with subsequent electrophilic functionalization, offers a one‐pot, two‐step modular strategy for synthesizing chiral α‐quaternary pyrrolines with precise chirality relay and high structural diversity.
Xingdie Yang +6 more
wiley +1 more source
Oxadendralenes in asymmetric organocatalysis for the construction of tetrahydroisochromenes
Chemical Science, 2016 Oxadendralenes are integrated in a novel manner into a one-pot cascade utilizing synergistic catalysis for the construction of valuable and complex bicyclic heterocyclic scaffolds.
Hammer, Niels +4 more
openaire +4 more sources
Evolution in the Test-Tube as a Means to Create Selective Biocatalysts
CHIMIA, 2007 The development of chiral catalysts for use in synthetic organic chemistry is traditionally associated with progress in asymmetric transition metal catalysis or organocatalysis.
Manfred T. Reetz
doaj +1 more source
Selective N‐Functionalization of Pyrazoles
European Journal of Organic Chemistry, Volume 29, Issue 40, 27 October 2026.This review traces the evolution of regioselective N‐functionalization strategies for pyrazoles, a key class of nitrogen heterocycles widely used in medicinal chemistry. Due to rapid tautomerism, N‐functionalization often lacks selectivity, leading to poor and unpredictable regioisomeric outcomes.
Lucas Popek +2 more
wiley +1 more source
ORGANOCATÁLISE ENANTIOSSELETIVA: EVOLUÇÃO E ASPECTOS RECENTES
Química NovaIn the last two decades, enantioselective organocatalysis has established itself as one of the three pillars of asymmetric catalysis. The rapid growth in the area is due to the rationalization of organocatalysis based on the generic modes of catalyst ...
Fernanda G. Finelli +2 more
doaj +1 more source