Results 61 to 70 of about 395,120 (176)
Pickering interfacial catalysts for asymmetric organocatalysis
, 2022 Proline-catalyzed aldol reactions have been developed as an important toolbox for the synthesis of valuable chiral intermediates, giving birth to asymmetric organocatalysis.
Sun, Zhiyong +3 more
core +1 more source
On Rational Design of Stereodivergent Organocatalysis Controlled by Selective Hydration [PDF]
, 2023 Stereodivergent asymmetric synthesis via slightly tuning the catalytic conditions is very attractive for early-stage drug discovery, because it is a very time efficient and economical method for obtaining all potential biologically active diastereomers ...
Liuqun, Gu
core +1 more source
Recent advances in organocatalytic atroposelective reactions
Beilstein Journal of Organic ChemistryAxial chirality is present in a variety of naturally occurring compounds, and is becoming increasingly relevant also in medicine. Many axially chiral compounds are important as catalysts in asymmetric catalysis or have chiroptical properties. This review
Henrich Szabados, Radovan Šebesta
doaj +1 more source
Advances in Organic and Organic-Inorganic Hybrid Polymeric Supports for Catalytic Applications
Molecules, 2016 In this review, the most recent advances (2014–2016) on the synthesis of new polymer-supported catalysts are reported, focusing the attention on the synthetic strategies developed for their preparation.
Anna Maria Pia Salvo +2 more
doaj +1 more source
Transformative Chemistry, EarlyView.Direct asymmetric α‐C conjugate addition of aminoacetonitrile enabled by carbonyl/iminium double activation, together with subsequent electrophilic functionalization, offers a one‐pot, two‐step modular strategy for synthesizing chiral α‐quaternary pyrrolines with precise chirality relay and high structural diversity.
Xingdie Yang +6 more
wiley +1 more source
A Genetic Optimization Strategy with Generality in Asymmetric Organocatalysis as Primary Target [PDF]
, 2023 A catalyst possessing a broad substrate scope, in terms of both turnover and enantioselectivity, is sometimes called “general”. Despite their great utility in asymmetric synthesis, truly general catalysts are difficult or expensive to discover via ...
Alexander, Makaveev +5 more
core +2 more sources
Advances on Greener Asymmetric Synthesis of Antiviral Drugs via Organocatalysis
Pharmaceuticals, 2021 Viral infections cause many severe human diseases, being responsible for remarkably high mortality rates. In this sense, both the academy and the pharmaceutical industry are continuously searching for new compounds with antiviral activity, and in ...
Everton M. da Silva +2 more
doaj +1 more source
Alkoxyallenes in Modern Synthesis: Reactivity, Catalysis, and Complexity Generation
Advanced Synthesis &Catalysis, Volume 368, Issue 17, 1 September 2026.The last decade has witnessed a remarkable transformation in alkoxyallene chemistry. Although historically employed as synthetic equivalents of acrolein or as versatile 3C synthons, alkoxyallenes are now increasingly recognized as highly adaptable platforms for synthetic design.
A. Lanfranco +5 more
wiley +1 more source
Oxadendralenes in asymmetric organocatalysis for the construction of tetrahydroisochromenes
Chemical Science, 2016 Oxadendralenes are integrated in a novel manner into a one-pot cascade utilizing synergistic catalysis for the construction of valuable and complex bicyclic heterocyclic scaffolds.
Hammer, Niels +4 more
openaire +4 more sources
Machine Learning for Synthetic Organic Chemistry: Methods, Applications, and Best Practices
Angewandte Chemie Novit, Volume 2, Issue 3, September 2026.Artificial intelligence (AI) and machine learning (ML) are increasingly reshaping experimental chemistry. This review maps the challenges of synthetic organic chemistry to modern digital tools that can help address them. While focusing on the practical application of ML tools in real‐world laboratory settings, we outline prerequisites, emerging ...
Niklas Hölter +3 more
wiley +1 more source