Results 81 to 90 of about 395,120 (176)

Chiral Tertiary Sulfonium Salts as Effective Catalysts for Asymmetric Base-Free Neutral Phase-Transfer Reactions [PDF]

, 2017
Although chiral quaternary ammonium and phosphonium salts are commonly used for asymmetric organocatalysis, the catalytic ability of chiral tertiary sulfonium salts has yet to be demonstrated in asymmetric synthesis.
Maruoka, Keiji, Keiji Maruoka, Shirakawa, Seiji, Shiyao Liu, Liu, Shiyao, Seiji Shirakawa   +5 more
core   +1 more source

Reações de organocatálise com aminas quirais: aspectos mecanísticos e aplicações em síntese orgânica Organocatalysis reactions with chiral amines: mechanistic aspects and use on organic synthesis

Química Nova, 2009
The philosophy of organocatalysis is based on the utilization of organic compounds to catalyze organic transformations without the intervention of metals.
Giovanni W. Amarante, Fernando Coelho
doaj   +1 more source

The Use of N-iPr-2,2'-bipyrrolidine Derivatives as Organocatalysts for Asymmetric Michael Additions

CHIMIA, 2006
The recent rapid growth of organocatalysis has shown a new approach in organic chemistry and presents the obvious advantage in the avoidance of expensive and often toxic metals.
Sarah Mossé, Olivier Andrey, Alexandre Alexakis   +2 more
doaj   +1 more source

N-Heterocyclic Carbenes in Asymmetric Organocatalysis: Methods and Applications

Asymmetric organocatalysis with N -Heterocyclic carbenes (NHCs) has been recognized as a powerful platform for diverse transformations exploiting both umpolung and non-umpolung reactivity.
De Risi, Carmela, Massi, Alessandro
core   +1 more source

Asymmetric organocatalysis and the nitro group functionality

, 2013
The nitro group is an exceptionally versatile functional group, not only because it is essentially a masked amine, but also because its chemistry can be exploited in a number of useful ways. Asymmetric organocatalysis in particular has capitalized on the
Aitken, Lewis S., Cobb, Andre, Arezki, Natasha R., Arezki, Natasha, Aitken, Lewis, Dell'Isola, Antonio, Cobb, Alexander J. A.; id_orcid   +6 more
core   +1 more source

Enantioselective α-heterofunctionalization reactions of catalytically generated C1-Lewis base enolates

Tetrahedron Chem
Chiral Lewis base (LB) organocatalysis has emerged as a powerful covalent catalysis concept which allows for highly selective asymmetric C–C and C-heteroatom bond formations.
Magdalena Piringer, Lotte Stockhammer, Lukas Vogl, David Weinzierl, Paul Zebrowski, Mario Waser   +5 more
doaj   +1 more source

Asymmetric Synthesis of 2-Arylethylamines: A Metal-Free Review of the New Millennium

Molecules
2-Arylethylamines are presented in several natural bioactive compounds, as well as in nitrogen-containing drugs. Their ability to surpass the blood–brain barrier makes this family of compounds of especial interest in medicinal chemistry.
Alejandro Manchado, Ángel García-González, Carlos T. Nieto, David Díez, Narciso M. Garrido   +4 more
doaj   +1 more source

Three-Component Approach to Densely Functionalized Trifluoromethyl Allenols by Asymmetric Organocatalysis. [PDF]

J Am Chem Soc, 2023
Deliaval M, Jayarajan R, Eriksson L, Szabó KJ.   +3 more
europepmc   +1 more source

Catalytic asymmetric synthesis of biologically important 3-hydroxyoxindoles: an update

Beilstein Journal of Organic Chemistry, 2016
Oxindole scaffolds are prevalent in natural products and have been recognized as privileged substructures in new drug discovery. Several oxindole-containing compounds have advanced into clinical trials for the treatment of different diseases. Among these
Bin Yu, Hui Xing, De-Quan Yu, Hong-Min Liu   +3 more
doaj   +1 more source

(S)- and (R)-5-Pyrrolidin-2-yl-1H-tetrazoles: Enantiomeric Organocatalysts of Broad Utility in Organic Synthesis

CHIMIA, 2007
This mini-review concerns the broad application of (S)- and (R)-5-pyrrolidin-2-yl-1H-tetrazoles as organocatalysts. A summary of methods for their synthesis is followed by a discussion of the general reaction mechanism and subsequent analysis of
Deborah A. Longbottom, Vilius Franckevičius, Steven V. Ley   +2 more
doaj   +1 more source