Results 91 to 100 of about 415,153 (176)

Diastereoselective Synthesis of (–)-Bestatin, Epibestatin, Phebestin and (3S,4R)-4-Amino-3-hydroxy-5-phenylpentanoic Acid from an Aldehyde Derived from d-Phenylalanine

open access: yesSynOpen, 2019
A convenient and efficient method for the synthesis of (–)-bestatin, epibestatin, phebestin, and (3S,4R)-4-amino-3-hydroxy-5-phenylpentanoic acid is reported. The key step is a proline-catalyzed α-hydroxylation of an aldehyde derived from d-phenylalanine,
Vipin Kumar Jain
doaj   +1 more source

Organocatalytic tandem Michael addition reactions: A powerful access to the enantioselective synthesis of functionalized chromenes, thiochromenes and 1,2-dihydroquinolines

open access: yesBeilstein Journal of Organic Chemistry, 2012
Enantioselective organocatalysis has become a field of central importance within asymmetric chemical synthesis and appears to be efficient approach toward the construction of complex chiral molecules from simple achiral materials in one-pot ...
Chittaranjan Bhanja   +3 more
doaj   +1 more source

(Thio)urea-mediated synthesis of functionalized six-membered rings with multiple chiral centers

open access: yesBeilstein Journal of Organic Chemistry, 2016
Organocatalysis, now running its second decade of life, is being considered one of the main tools a synthetic chemist has to perform asymmetric catalysis. In this review the synthesis of six-membered rings, that contain multiple chiral centers, either by
Giorgos Koutoulogenis   +2 more
doaj   +1 more source

New Concepts for Organocatalysis

open access: yes, 2008
Organocatalysis, catalysis with low-molecular weight catalysts in which a metal is not part of the catalytic principle or the reaction substrate, can be as efficient and selective as metal- or biocatalysis.
List, B., B. List, Pan, S., S. C. Pan
core   +1 more source

Synthesis of the Southern Tripeptide (C1–N12) of Sanglifehrins Using Asymmetric Organocatalysis

open access: yes, 2014
The tripeptide southern region of the novel cyclophilin binding natural product macrolides, namely sanglifehrins, is synthesized involving asymmetric organocatalysis as chirality-inducing step.
Laghuvarapu Radhika (626159)   +1 more
core   +1 more source

Asymmetric Counteranion-Directed Lewis Acid Organocatalysis.

open access: yes, 2014
This work describes studies on asymmetric counteranion-directed Lewis acid organocatalysis. In the first part, the development of a catalytic asymmetric Hosomi–Sakurai reaction using BINOL-derived disulfonimides is described. Good to excellent yields and
van Gemmeren, M.
core  

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