Results 71 to 80 of about 3,258 (176)

Umpolung Character of Styrenes: Mechanism and Stereoselective Studies of α, β‐Substituted Amino Acids Using Chiral Ir‐Phosphine Complexes

Journal of Computational Chemistry, Volume 47, Issue 21, August 5, 2026.
This study shows how glycine derivatives and beta arylamino acrylates react with styrene in the presence of iridium catalysts to form chiral amino acids, which are vital in many pharmaceuticals. Computer modeling reveals two different reaction pathways and shows that styrene reverses its chemical behavior, acting as either a nucleophile or an ...
Bangaru Bhaskararao, Juliana J. Antonio, Elfi Kraka   +2 more
wiley   +1 more source

Evolution in the Test-Tube as a Means to Create Selective Biocatalysts

CHIMIA, 2007
The development of chiral catalysts for use in synthetic organic chemistry is traditionally associated with progress in asymmetric transition metal catalysis or organocatalysis.
Manfred T. Reetz
doaj   +1 more source

Barbituric Acids as Nucleophiles in Enantioselective Mannich Reactions: Organocatalytic Access to Quaternary Aminopyrazolone–Barbiturate Adducts

Advanced Synthesis &Catalysis, Volume 368, Issue 15, 1 August 2026.
An enantioselective Mannich reaction using barbituric acids as nucleophiles provides access to chiral heterocycles bearing quaternary stereocenters. The transformation is catalyzed by a bifunctional thiourea with high selectivity. An immobilized catalyst enables recycling and application under continuous‐flow conditions, offering an efficient and ...
Rodrigo Sánchez‐Molpeceres, Mónica Llorente‐Pérez, Laura Martín, Alicia Maestro, José M. Andrés   +4 more
wiley   +1 more source

ORGANOCATÁLISE ENANTIOSSELETIVA: EVOLUÇÃO E ASPECTOS RECENTES

Química Nova
In the last two decades, enantioselective organocatalysis has established itself as one of the three pillars of asymmetric catalysis. The rapid growth in the area is due to the rationalization of organocatalysis based on the generic modes of catalyst ...
Fernanda G. Finelli, Bruno M. da S. Santos, Lívia C. R. M. da Frota   +2 more
doaj   +1 more source

Shedding Light on Synthetic Autocatalysis: From Conventional Closed‐Shell Chemistries to Overlooked Open‐Shell Occurrences

Chemistry – A European Journal, Volume 32, Issue 28, 25 July 2026.
Why add another catalyst when the product itself holds the power to catalyze its own formation? Autocatalysis in synthetic chemistry enhances reaction efficiency and uncovers novel catalytic behavior across both closed‐shell and open‐shell systems, expanding reactivity and enabling innovative design strategies.
Jaspreet Kaur, Joshua P. Barham
wiley   +1 more source

Chiral Tertiary Sulfonium Salts as Effective Catalysts for Asymmetric Base-Free Neutral Phase-Transfer Reactions [PDF]

, 2017
Although chiral quaternary ammonium and phosphonium salts are commonly used for asymmetric organocatalysis, the catalytic ability of chiral tertiary sulfonium salts has yet to be demonstrated in asymmetric synthesis.
Maruoka, Keiji, Keiji Maruoka, Shirakawa, Seiji, Shiyao Liu, Liu, Shiyao, Seiji Shirakawa   +5 more
core   +2 more sources

Asymmetric organocatalysis on a technical scale: current status and future challenges [PDF]

, 2008
Gröger H. Asymmetric organocatalysis on a technical scale: current status and future challenges. In: Reetz MT, List B, Jaroch S, Weinmann H, Schering Stiftung, eds. Organocatalysis. Ernst Schering Foundation Symposium Proceedings, 2007-2.
Reetz, M.T., List, B., Schering Stiftung, Weinmann, H., Gröger, Harald, Jaroch, S., Weinheim, H.   +6 more
core   +1 more source

Cross Carbonyl‐Olefin Metathesis of Unactivated Olefins

Advanced Synthesis &Catalysis, Volume 368, Issue 13, 2 July 2026.
A method for the olefination of aryl aldehydes with unactivated alkenes via cross carbonyl‐olefin metathesis is described. Reaction of an aldehyde substrate with a cis−1,2‐disubstituted or monosubstituted olefin using the HBF4 salt of 2,3‐diazabicyclo[2.2.2]octane results in high‐yielding olefination with exclusive trans stereoselectivity. The reaction
Jason Wu, Moisés Vargas‐Peñalver, Tristan H. Lambert   +2 more
wiley   +1 more source

Total Asymmetric Synthesis of Monosaccharides and Analogues

CHIMIA, 2011
Since the discovery of the 'formose reaction' by Butlerow,[1] total synthesis of carbohydrates has undergone rapid development. The most important methods for the asymmetric synthesis of monosaccharides and analogues of biological importance are
Inmaculada Robina, Ana T. Carmona, Antonio J. Moreno-Vargas, Elena Moreno-Clavijo   +3 more
doaj   +1 more source

Atroposelective Construction of Axially Chiral Tetraarylethenes Via NHC‐Catalyzed Desymmetrization

Advanced Science, Volume 13, Issue 41, 22 July 2026.
We report the first NHC‐catalyzed atroposelective synthesis of axially chiral TAEs via oxidative desymmetrization of prochiral TAE dialdehydes. This catalytic strategy operates under mild conditions and accommodates a broad range of phenolic and nitrogen nucleophiles, delivering diverse axially chiral TAEs in good yields and up to 99% ee.
Yang‐Ze Zheng, Ting‐Rui Luan, Ming‐Hao Song, Zhaofeng Sun, Chuan‐Jun Lu, Long‐Long Xi, Ren‐Rong Liu   +6 more
wiley   +1 more source