Results 51 to 60 of about 415,153 (176)

Activation of Metal Complexes With Ultrasound Waves for Targeted Anticancer Therapy

Angewandte Chemie International Edition, EarlyView.
Ultrasound enables non‐invasive activation of metal‐based therapeutics deep within tumors. Acoustic cavitation can drive sonodynamic reactive oxygen species generation or mechanochemical metal–ligand bond dissociation, enabling controlled release of bioactive payloads.
Félix Grosjean, Nicolás Montesdeoca, Gilles Berger, Johannes Karges   +3 more
wiley   +1 more source

Recent advances in organocatalytic atroposelective reactions

Beilstein Journal of Organic Chemistry
Axial chirality is present in a variety of naturally occurring compounds, and is becoming increasingly relevant also in medicine. Many axially chiral compounds are important as catalysts in asymmetric catalysis or have chiroptical properties. This review
Henrich Szabados, Radovan Šebesta
doaj   +1 more source

Asymmetric Organocatalysis of 4 + 3 Cycloaddition Reactions

, 2016
Treatment of several 4-trialkylsilyloxypentadienals with a chiral secondary amine, trifluoroacetic acid, and a diene resulted in the formation of 4 + 3 cycloaddition products, which were enantiomerically enriched.
Sumrit Wacharasindhu (2018968), Michael Harmata (746967), Patrick Kirchhoefer (2991312), Sunil K. Ghosh (2202520), Xuechuan Hong (790032)   +4 more
core   +2 more sources

Organocatalytic Enantioselective Addition of Malonates to Cyclic Imines: A Short Total Synthesis of Tetraponerine T‐1

Angewandte Chemie, Volume 138, Issue 38, 14 September 2026.
A stereoselective functionalization method of cyclic imines under mild organocatalytic conditions was developed. Bifunctional cinchona alkaloid catalysts combined with carefully optimized reaction conditions to suppress background reactivity enabled highly enantio‐ and diastereoselective addition reactions of malonates to cyclic imines.
Frederic Kölblin, Helma Wennemers
wiley   +2 more sources

Advances in Organic and Organic-Inorganic Hybrid Polymeric Supports for Catalytic Applications

Molecules, 2016
In this review, the most recent advances (2014–2016) on the synthesis of new polymer-supported catalysts are reported, focusing the attention on the synthetic strategies developed for their preparation.
Anna Maria Pia Salvo, Francesco Giacalone, Michelangelo Gruttadauria   +2 more
doaj   +1 more source

Iso‐Tellurazole N‐Oxides Assemble Adaptively Folded Macrocyclic Dodecamers

Chemistry – A European Journal, EarlyView.
Te…O Chalcogen bonding links twelve molecules into a ring that wraps itself around molecular guests. ABSTRACT Self‐assembled macrocyclic dodecamers were found in the crystals of new pseudo‐polymorphs of iso‐tellurazole N‐oxides. These structures are formed by molecules connected by NTe…O chalcogen bonds and are folded in a pattern that defines 89–153 ...
Jin Z. Wang, Phillip MacDougall, Mich W. Zeng, James F. Britten, Ignacio Vargas‐Baca   +4 more
wiley   +1 more source

Synthesis and use of a stable aminal derived from TsDPEN in asymmetric organocatalysis [PDF]

, 2010
A stable aminal formed stereoselectively from (R,R)-N-tosyl-1,2-diphenyl-1,2-ethylenediamine (TsDPEN) is capable of asymmetric organocatalysis of Diels-Alder and alpha-amination reactions of ...
Martin Wills, Silvia Gosiewska, Wills, Martin, Clarkson, Guy J., Rina Soni, Gosiewska, Silvia, Guy J. Clarkson, Soni, Rina   +7 more
core   +1 more source

Advances on Greener Asymmetric Synthesis of Antiviral Drugs via Organocatalysis

Pharmaceuticals, 2021
Viral infections cause many severe human diseases, being responsible for remarkably high mortality rates. In this sense, both the academy and the pharmaceutical industry are continuously searching for new compounds with antiviral activity, and in ...
Everton M. da Silva, Hérika D. A. Vidal, Arlene G. Corrêa   +2 more
doaj   +1 more source

Towards Halogen Bonding MOFs: Networking With a Polyiodinated and Perfluorinated Terphenyl Ligand and Divalent Zinc

Chemistry – A European Journal, EarlyView.
One ligand, three new architectures with different intermolecular interactions: a polyhalogenated terphenyl linker with carboxyl groups coordinates Zn2+ to form (i) a metal‐containing hydrogen‐bonded organic framework; (ii) a metal‐organic framework or (iii) one‐dimensional metal‐organic chains with intermolecular halogen bonding and hydrogen bonding ...
Elad Gaver, Christoph J. Vonnemann, Julian Stoesser, Jennifer A. E. Rühle, Mark A. Iron, Linda J. W. Shimon, Michal Lahav, Stefan M. Huber, Milko E. van der Boom   +8 more
wiley   +1 more source

Chiral Tertiary Sulfonium Salts as Effective Catalysts for Asymmetric Base-Free Neutral Phase-Transfer Reactions [PDF]

, 2017
Although chiral quaternary ammonium and phosphonium salts are commonly used for asymmetric organocatalysis, the catalytic ability of chiral tertiary sulfonium salts has yet to be demonstrated in asymmetric synthesis.
Maruoka, Keiji, Keiji Maruoka, Shirakawa, Seiji, Shiyao Liu, Liu, Shiyao, Seiji Shirakawa   +5 more
core   +1 more source