Results 51 to 60 of about 3,258 (176)
Asymmetric Organocatalysis of 4 + 3 Cycloaddition Reactions [PDF]
, 2016 Treatment of several 4-trialkylsilyloxypentadienals with a chiral secondary amine, trifluoroacetic acid, and a diene resulted in the formation of 4 + 3 cycloaddition products, which were enantiomerically enriched.
Sumrit Wacharasindhu (2018968) +4 more
core +3 more sources
(2R,4R)-2-Hydroxy-4-(2-methoxyphenyl)bicyclo[3.3.1]nonan-9-one
Acta Crystallographica Section E, 2009 The title compound, C16H20O3, contains a bicyclic ring system with two chiral centers. The crystal structure is stabilized by intermolecular O—H...O hydrogen bonds.
Shuping Luo +4 more
doaj +1 more source
Asymmetric organocatalysis and the nitro group functionality [PDF]
, 2013 The nitro group is an exceptionally versatile functional group, not only because it is essentially a masked amine, but also because its chemistry can be exploited in a number of useful ways. Asymmetric organocatalysis in particular has capitalized on the
Aitken, Lewis S. +6 more
core +1 more source
Angewandte Chemie, Volume 138, Issue 28, 6 July 2026.A catalytic network embedding a formal rearrangement enables the first catalytic enantioselective multicomponent reaction (MCR) of sulfur ylides. In the presence of a bulky chiral phosphoric acid, the reaction combines sulfoxonium ylides, aldehydes and thiols, and affords synthetically versatile β‐hydroxy‐α‐sulfanyl carbonyl compounds in ...
Nicolò Santarelli +10 more
wiley +2 more sources
Molecules, 2016 The organocatalysis-based dynamic kinetic resolution (DKR) process has proved to be a powerful strategy for the construction of chiral compounds. In this feature review, we summarized recent progress on the DKR process, which was promoted by chiral ...
Pan Li +3 more
doaj +1 more source
Nature Communications, 2023 The discovery of highly enantioselective catalysts and elucidating their generality face great challenges due to the complex multidimensional chemical space of asymmetric catalysis and inefficient screening methods.
Wenjing Nie +5 more
doaj +1 more source
Chemistry – A European Journal, EarlyView.Aminocatalytically generated isobenzofulvenes and 3‐oxidopyridinium betaines act as ambiphilic reaction partners in orbital‐symmetry‐allowed [10+4] cycloadditions or formally symmetry‐forbidden concerted thermal [10+6] cycloadditions. The reaction furnishes three cycloadducts: one [10+4] cycloadduct and two regioisomeric [10+6] cycloadducts.
Jonas Faghtmann +7 more
wiley +1 more source
A One-Pot Tandem Strategy in Catalytic Asymmetric Vinylogous Aldol Reaction of Homoallylic Alcohols
Molecules, 2016 Reported is a rationally-designed one-pot sequential strategy that allows homoallylic alcohols to be employed in a catalytic, asymmetric, direct vinylogous aldol reaction with a series of activated acyclic ketones, including trifluoromethyl ketones, γ ...
Xufeng Hou +3 more
doaj +1 more source
Flipping the Card With Enantiodivergent Organocatalysis
Chemistry – A European Journal, EarlyView.This minireview elaborates on recent organocatalytic strategies for achieving enantiodivergence—the ability to access both product enantiomers using a single chiral catalyst. It highlights how achiral stimuli, such as solvent polarity and chemical additives, along with minimal catalyst modifications, trigger stereochemical inversions in reactions ...
Debora Iapadre +3 more
wiley +1 more source
Organocatalytic Formal (3+2+1)‐Cycloaddition of Allenoates, Michael Acceptors, and Carbaldehydes
Chemistry – A European Journal, EarlyView.The use of secondary amine Lewis base organocatalysts allows for the unprecedented activation of allenoates for formal (3+2+1)‐cycloadditions with Michael acceptors and aromatic carbaldehydes. ABSTRACT Employing secondary amines as covalently interacting Lewis basic organocatalysts allows for the activation of electron‐deficient allenes (allenoates ...
David Naderer +5 more
wiley +1 more source