Results 211 to 220 of about 83,214 (263)

Kappa opioid receptor internalisation-induced p38 nuclear translocation suppresses glioma progression. [PDF]

Br J Anaesth
Li Y, Wang W, She H, Cui Z, Liu Z, Yang H, Zhang J, Zhou X, Bao D, Yao Y, Luo S, Cai R, Shi Y, Ping YF, Mao Q.   +14 more
europepmc   +1 more source

Prospective Evaluation of the Effectiveness of Brachial Plexus Nerve Block During the Perioperative Period in Long-Term Opioid Users Undergoing Upper Extremity Surgery - A Case Series. [PDF]

Local Reg Anesth
Huettner D, Qiu Y, Rosario BL, Orebaugh S.   +3 more
europepmc   +1 more source

Semi-synthesis in the exploration of opioid-targeting natural products.

Nat Prod Rep
Riley AP.
europepmc   +1 more source

Some of the next articles are maybe not open access.

Related searches:

Antagonists of the kappa opioid receptor

Bioorganic & Medicinal Chemistry Letters, 2014
The research community has increasingly focused on the development of OPRK antagonists as pharmacotherapies for the treatment of depression, anxiety, addictive disorders and other psychiatric conditions produced or exacerbated by stress. Short-acting OPRK antagonists have been recently developed as a potential improvement over long-acting prototypic ...
Mariangela, Urbano, Miguel, Guerrero, Hugh, Rosen, Edward, Roberts   +3 more
openaire   +2 more sources

Specific kappa opioid receptor agonists.

Farmaco (Societa chimica italiana : 1989), 2000
The results of studies on the design of a heterocyclic scaffold for the dynorphin A pharmacophore and on structure-affinity relationships in the MPCB/CCB series are described. The representative ligands provide insights to binding modes of benzomorphan derivatives to the kappa opioid receptor.
RONSISVALLE, Giuseppe, MARRAZZO, Agostino, PASQUINUCCI, Lorella Giuseppina, PREZZAVENTO O, PAPPALARDO M, VITTORIO F.   +5 more
openaire   +3 more sources

TENA, a selective kappa opioid receptor antagonist

Life Sciences, 1985
A number of opioid antagonists (TENA, naloxone, Mr 2266, WIN 44441) were evaluated for their selectivity in antagonizing the effect of mu, kappa, and delta agonists in the guinea pig ileum (GPI) and mouse vas deferens (MVD) preparations. Among these four antagonists, TENA was the most potent and the only ligand which was selective for kappa receptors ...
P S, Portoghese, A E, Takemori
openaire   +2 more sources

Involvement of dynorphin and the kappa opioid receptor in feeding

Peptides, 1983
Dynorphin-(1-17) produces a highly specific increase in food ingestion. Similar enhancement of food ingestion is found with dynorphin fragments (1-10), (1-11), (1-13) and (3-13) but not with (1-8) and (1-9). Dynorphin B (rimorphin) also enhances food intake.
J E, Morley, A S, Levine
openaire   +2 more sources

The kappa-opioid receptor: Evidence for the different subtypes

Life Sciences, 1993
Classification of drugs acting on the kappa-opioid receptors seems to be difficult, since some of these ligands are also sigma agonists and/or display non-opioid actions as well. Furthermore, certain benzomorphans having kappa-agonistic character, are shown to be mu-antagonists too.
M, Wollemann, S, Benyhe, J, Simon
openaire   +2 more sources